SOD mimetics are coming of age. (Q34743335)

4 August 2017

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title

SOD mimetics are coming of age. (English)

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4 August 2017

3

Salvatore Cuzzocrea

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4 August 2017

Daniela Salvemini

1

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4 August 2017

Dennis P Riley

series ordinal

2

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4 August 2017

publication date

1 May 2002

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Nature Reviews Drug Discovery

4 August 2017

published in

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4 August 2017

volume

1

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4 August 2017

issue

5

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4 August 2017

page(s)

367-374

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Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury

4 August 2017

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Mice lacking extracellular superoxide dismutase are more sensitive to hyperoxia

21 January 2018

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Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice

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Mitochondrial disease in superoxide dismutase 2 mutant mice

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21 January 2018

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Protective effects of a superoxide dismutase mimetic and peroxynitrite decomposition catalysts in endotoxin-induced intestinal damage

21 January 2018

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Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide

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Inactivation of catecholamines by superoxide gives new insights on the pathogenesis of septic shock

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Simultaneous overexpression of copper- and zinc-containing superoxide dismutase and catalase retards age-related oxidative damage and increases metabolic potential in Drosophila melanogaster.

21 January 2018

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Prospects for the use of antioxidant therapies

21 January 2018

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Effect of a superoxide dismutase derivative on cold-induced brain edema

21 January 2018

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Cold-induced brain edema and infarction are reduced in transgenic mice overexpressing CuZn-Superoxide dismutase

21 January 2018

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Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia

21 January 2018

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Prevention of reperfusion-induced, free radical-mediated acute endothelial injury by superoxide dismutase as an effective tool to delay/prevent chronic renal allograft failure: a review

21 January 2018

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Participation of superoxide anions at the prostaglandin phase of carrageenan foot-oedema

21 January 2018

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SOD2: a new type of tumor-suppressor gene?

21 January 2018

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Increased manganese superoxide dismutase expression suppresses the malignant phenotype of human melanoma cells

21 January 2018

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Expression of manganese superoxide dismutase promotes cellular differentiation

21 January 2018

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Tat protein of human immunodeficiency virus type 1 represses expression of manganese superoxide dismutase in HeLa cells

21 January 2018

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Oxidative stress and neuroAIDS: triggers, modulators and novel antioxidants.

21 January 2018

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Pharmaceutical studies for gene therapy: expression of human Cu, Zn-superoxide dismutase gene transfected by lipofection in rat skin fibroblasts

21 January 2018

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Potentiometric titrations and oxidation-reduction potentials of manganese and copper-zinc superoxide dismutases

21 January 2018

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Metalloporphyrins are potent inhibitors of lipid peroxidation

21 January 2018

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Evaluation of the relative contribution of nitric oxide and peroxynitrite to the suppression of mitochondrial respiration in immunostimulated macrophages using a manganese mesoporphyrin superoxide dismutase mimetic and peroxynitrite scavenger

21 January 2018

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Compounds I of catalase and horse radish peroxidase: pi-cation radicals

21 January 2018

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Characterization of the cytoprotective action of peroxynitrite decomposition catalysts

21 January 2018

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Beneficial effects of Mn(III)tetrakis (4-benzoic acid) porphyrin (MnTBAP), a superoxide dismutase mimetic, in carrageenan-induced pleurisy

21 January 2018

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The potential role of peroxynitrite in the vascular contractile and cellular energetic failure in endotoxic shock

21 January 2018

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Pharmacological manipulation of the inflammatory cascade by the superoxide dismutase mimetic, M40403

21 January 2018

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Protective effects of a new stable, highly active SOD mimetic, M40401 in splanchnic artery occlusion and reperfusion

21 January 2018

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Amelioration of joint disease in a rat model of collagen-induced arthritis by M40403, a superoxide dismutase mimetic

21 January 2018

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The formation of peroxynitrite in vivo from nitric oxide and superoxide

21 January 2018

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Oxidative damage and tyrosine nitration from peroxynitrite

21 January 2018

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Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor

21 January 2018

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Nitric oxide activates cyclooxygenase enzymes.

21 January 2018

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Inhibition of poly (ADP-ribose) synthetase attenuates neutrophil recruitment and exerts antiinflammatory effects

21 January 2018

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Role of O2- in neutrophil recruitment into sites of dermal and pulmonary vasculitis

21 January 2018

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Monocyte stimulation by reactive oxygen species: role of superoxide and intracellular Ca2 .

21 January 2018

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Redox/ROS regulation of lipopolysaccharide-induced mitogen-activated protein kinase (MAPK) activation and MAPK-mediated TNF-alpha biosynthesis

21 January 2018

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The role of superoxide and nuclear factor-kappaB signaling in N-methyl-D-aspartate-induced necrosis and apoptosis

21 January 2018

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Function and activation of NF-kappa B in the immune system

21 January 2018

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Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

21 January 2018

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Superoxide dismutase for therapeutic use: clinical experience, dead ends and hopes

21 January 2018

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Effect of intra-articular orgotein versus a corticosteroid on rheumatoid arthritis of the knees

21 January 2018

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Intra-articular orgotein in osteoarthritis of the knee: a placebo-controlled efficacy, safety, and dosage comparison

21 January 2018

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Orgotein: a new antiinflammatory metalloprotein drug evaluation of clinical efficacy and safety in inflammatory conditions of the urinary tract

21 January 2018

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Orgotein (superoxide dismutase): a drug for the amelioration of radiation-induced side effects. A double-blind, placebo-controlled study in patients with bladder tumours

21 January 2018

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Superoxide: a two-edged sword

21 January 2018

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Interactive roles of superoxide and inducible nitric oxide synthase in rat intestinal injury provoked by non-steroidal anti-inflammatory drugs

21 January 2018

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Evidence of peroxynitrite involvement in the carrageenan-induced rat paw edema

21 January 2018

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Mechanism of site-selective DNA nicking by the hydrodioxyl (perhydroxyl) radical

31 March 2020

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Peroxynitrite formation from macrophage-derived nitric oxide

31 March 2020

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Pulse radiolytic investigations of superoxide catalyzed disproportionation. Mechanism for bovine superoxide dismutase

31 March 2020

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Mechanism of manganese catalase peroxide disproportionation: determination of manganese oxidation states during turnover

31 March 2020

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Transgenic models for the study of lung antioxidant defense: enhanced manganese-containing superoxide dismutase activity gives partial protection to B6C3 hybrid mice exposed to hyperoxia

31 March 2020

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Free radicals and inflammation: protection of synovial fluid by superoxide dismutase

31 March 2020

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Sustained limitation by superoxide dismutase of canine myocardial injury due to regional ischemia followed by reperfusion

31 March 2020

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Interstitial equilibration of superoxide dismutase correlates with its protective effect in the isolated rabbit heart

31 March 2020

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Superoxide dismutase: rationale for use in reperfusion injury and inflammation

31 March 2020

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Anti-inflammatory effects of recombinant human manganese superoxide dismutase on adjuvant arthritis in rats

31 March 2020

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Suppressive effect of recombinant human Cu, Zn-superoxide dismutase on lung metastasis of murine tumor cells

31 March 2020

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Clastogenic Factors In Plasma Of HIV-1 Infected Patients Activate HIV-1 Replication In Vitro: Inhibition By Superoxide Dismutase

31 March 2020

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Superoxide dismutase in development of obliterative bronchiolitis

31 March 2020

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Chronic obstructive pulmonary disease

31 March 2020

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The ortho effect makes manganese(III) meso-tetrakis(N-methylpyridinium-2-yl)porphyrin a powerful and potentially useful superoxide dismutase mimic

31 March 2020

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Manganic Porphyrins Possess Catalase Activity and Protect Endothelial Cells against Hydrogen Peroxide-Mediated Injury

31 March 2020

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Superoxide scavenging by Mn(II/III) tetrakis (1-methyl-4-pyridyl) porphyrin in mammalian cells

31 March 2020

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Potential role of the peroxynitrate-poly(ADP-ribose) synthetase pathway in a rat model of severe hemorrhagic shock

31 March 2020

1 reference

Salen-manganese complexes are superoxide dismutase-mimics

31 March 2020

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Prevention and suppression of autoimmune encephalomyelitis by EUK-8, a synthetic catalytic scavenger of oxygen-reactive metabolites

31 March 2020

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Computer-Aided Design (CAD) of Synzymes: Use of Molecular Mechanics (MM) for the Rational Design of Superoxide Dismutase Mimics

31 March 2020

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A nonpeptidyl mimic of superoxide dismutase with therapeutic activity in rats

31 March 2020

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Oxidative DNA damage induced by simultaneous generation of nitric oxide and superoxide

31 March 2020

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Peroxynitrite causes DNA damage and oxidation of thiols in rat thymocytes [corrected]

31 March 2020

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Role of poly(ADP-ribose) synthetase in inflammation and ischaemia-reperfusion

31 March 2020

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Protective effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthase in a carrageenan-induced model of local inflammation

31 March 2020

1 reference

Comparison of the cardiovascular effects of two novel superoxide dismutase mimetics, SC-55858 and SC-54417, in conscious dogs

31 March 2020

1 reference

Beneficial effects of peroxynitrite decomposition catalyst in a rat model of splanchnic artery occlusion and reperfusion

31 March 2020

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Effect of liposomal-encapsulated superoxide dismutase on active oxygen-related human disorders. A preliminary study

31 March 2020

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Intrasynovial orgotein therapy in rheumatoid arthritis

31 March 2020

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Clinical comparison of orgotein and methylprednisolone acetate in the treatment of osteoarthrosis of the knee joint

31 March 2020

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Use of superoxide dismutase (SOD) in patients with temporomandibular joint dysfunction--a preliminary study

31 March 2020

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Successful treatment of radiation-induced fibrosis using liposomal Cu/Zn superoxide dismutase: clinical trial

31 March 2020

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Stopped-flow kinetic analysis for monitoring superoxide decay in aqueous systems

31 March 2020

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Successful treatment of radiation-induced fibrosis using Cu/Zn-SOD and Mn-SOD: an experimental study

31 March 2020

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Superoxide dismutase (SOD) and the PAF-antagonist (BN 52021) reduce small intestinal damage induced by ischemia-reperfusion

31 March 2020

1 reference

7 January 2021

Hemorrhagic shock-induced bacterial translocation: the role of neutrophils and hydroxyl radicals

1 reference

7 January 2021

Reactions between nitric oxide, superoxide, and peroxynitrite: footprints of peroxynitrite in vivo

1 reference

7 January 2021

Salen-manganese complexes: combined superoxide dismutase/catalase mimics with broad pharmacological efficacy

1 reference

7 January 2021

Identifiers

DOI

10.1038/NRD796

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4 August 2017

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