Wnt signaling gradients establish planar cell polarity by inducing Vangl2 phosphorylation through Ror2 (Q34706774)

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22 January 2020

title

Wnt signaling gradients establish planar cell polarity by inducing Vangl2 phosphorylation through Ror2 (English)

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22 January 2020

1 reference

1

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Aris Economides

11

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22 January 2020

author name string

Hai Song

2

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22 January 2020

Kevin Bishop

3

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Gene Elliot

4

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Lisa Garrett

5

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Milton A English

6

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Philipp Andre

7

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James Robinson

8

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Raman Sood

9

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22 January 2020

Yasuhiro Minami

10

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22 January 2020

Yingzi Yang

12

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22 January 2020

language of work or name

English

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publication date

1 February 2011

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22 January 2020

number of pages

14

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based on heuristic

inferred from page(s)

published in

Developmental Cell

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22 January 2020

volume

20

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22 January 2020

issue

2

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22 January 2020

page(s)

163-176

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WNT5A/JNK and FGF/MAPK pathways regulate the cellular events shaping the vertebrate limb bud.

22 January 2020

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Planar cell polarity breaks bilateral symmetry by controlling ciliary positioning

7 July 2018

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7 July 2018

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Coupling between hydrodynamic forces and planar cell polarity orients mammalian motile cilia

7 July 2018

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Planar cell polarity: keeping hairs straight is not so simple

7 July 2018

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Planar polarization of node cells determines the rotational axis of node cilia.

7 July 2018

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Gradients and the specification of planar polarity in the insect cuticle.

7 July 2018

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Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure

7 July 2018

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WNT5A mutations in patients with autosomal dominant Robinow syndrome

7 July 2018

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Proximal events in Wnt signal transduction

7 July 2018

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7 July 2018

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Selective activation mechanisms of Wnt signaling pathways

7 July 2018

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Opposing Wnt pathways orient cell polarity during organogenesis

7 July 2018

1 reference

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Cthrc1 selectively activates the planar cell polarity pathway of Wnt signaling by stabilizing the Wnt-receptor complex

7 July 2018

1 reference

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Wnt5a control of cell polarity and directional movement by polarized redistribution of adhesion receptors

7 July 2018

1 reference

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Genetic interaction between members of the Vangl family causes neural tube defects in mice

7 July 2018

1 reference

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Planar polarity and tissue morphogenesis

7 July 2018

1 reference

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Planar cell polarity: one or two pathways?

7 July 2018

1 reference

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Wnt5a functions in planar cell polarity regulation in mice

7 July 2018

1 reference

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Mutations in VANGL1 associated with neural-tube defects

7 July 2018

1 reference

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Tissue/planar cell polarity in vertebrates: new insights and new questions

7 July 2018

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Frizzled/PCP signalling: a conserved mechanism regulating cell polarity and directed motility

7 July 2018

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Tissue, cellular and sub-cellular localization of the Vangl2 protein during embryonic development: effect of the Lp mutation

7 July 2018

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Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context

7 July 2018

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The Wnt signaling pathway in development and disease

7 July 2018

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The receptor tyrosine kinase Ror2 associates with and is activated by casein kinase Iepsilon

7 July 2018

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D4476, a cell-permeant inhibitor of CK1, suppresses the site-specific phosphorylation and nuclear exclusion of FOXO1a.

7 July 2018

1 reference

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Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent beta-catenin degradation

7 July 2018

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Wnt-5/pipetail functions in vertebrate axis formation as a negative regulator of Wnt/beta-catenin activity.

7 July 2018

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The receptor tyrosine kinase Ror2 is involved in non-canonical Wnt5a/JNK signalling pathway

7 July 2018

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Strabismus is asymmetrically localised and binds to Prickle and Dishevelled during Drosophila planar polarity patterning

7 July 2018

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A three-tiered mechanism for regulation of planar cell polarity.

7 July 2018

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Zebrafish trilobite identifies new roles for Strabismus in gastrulation and neuronal movements.

7 July 2018

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Loss of mRor1 enhances the heart and skeletal abnormalities in mRor2-deficient mice: redundant and pleiotropic functions of mRor1 and mRor2 receptor tyrosine kinases

7 July 2018

1 reference

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Severe neural tube defects in the loop-tail mouse result from mutation of Lpp1, a novel gene involved in floor plate specification

7 July 2018

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Morphogens: how big is the big picture?

7 July 2018

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Distinct mutations in the receptor tyrosine kinase gene ROR2 cause brachydactyly type B.

7 July 2018

1 reference

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Mutation of the gene encoding the ROR2 tyrosine kinase causes autosomal recessive Robinow syndrome

7 July 2018

1 reference

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Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062198

Ror2, encoding a receptor-like tyrosine kinase, is required for cartilage and growth plate development

7 July 2018

1 reference

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Sox9 is required for cartilage formation

7 July 2018

1 reference

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A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo

7 July 2018

1 reference

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Van Gogh: a new Drosophila tissue polarity gene

7 July 2018

1 reference

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Positional information and the spatial pattern of cellular differentiation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062198

Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development

7 July 2018

1 reference

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VANGL2 mutations in human cranial neural-tube defects

7 July 2018

2 references

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26 October 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062198

Vangl2 directs the posterior tilting and asymmetric localization of motile primary cilia.

9 December 2018

1 reference

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WNT11 acts as a directional cue to organize the elongation of early muscle fibres

26 October 2018

1 reference

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CKIepsilon/discs overgrown promotes both Wnt-Fz/beta-catenin and Fz/PCP signaling in Drosophila

26 October 2018

1 reference

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Planar polarity is positively regulated by casein kinase Iepsilon in Drosophila

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062198

Identification and developmental expression pattern of van gogh-like 1, a second zebrafish strabismus homologue

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062198

Wnt5a and Wnt5b exhibit distinct activities in coordinating chondrocyte proliferation and differentiation

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062198

The Xenopus receptor tyrosine kinase Xror2 modulates morphogenetic movements of the axial mesoderm and neuroectoderm via Wnt signaling

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062198

Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062198

Recessive Robinow syndrome, allelic to dominant brachydactyly type B, is caused by mutation of ROR2.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062198

Wnt5 is required for tail formation in the zebrafish embryo.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062198

Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062198

Mouse Ror2 receptor tyrosine kinase is required for the heart development and limb formation

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21316585

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.DEVCEL.2011.01.001

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21316585 AND SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21316585 AND SRC:MED&resulttype=core&format=json

22 January 2020

PubMed publication ID

21316585

1 reference