Novel multi-component nanopharmaceuticals derived from poly(ethylene) glycol, retro-inverso-Tat nonapeptide and saquinavir demonstrate combined anti-HIV effects (Q34691351)

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English	Novel multi-component nanopharmaceuticals derived from poly(ethylene) glycol, retro-inverso-Tat nonapeptide and saquinavir demonstrate combined anti-HIV effects	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Novel multi-component nanopharmaceuticals derived from poly(ethylene) glycol, retro-inverso-Tat nonapeptide and saquinavir demonstrate combined anti-HIV effects (English)

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

1 reference

based on heuristic

inferred from title

author name string

Li Wan

1

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Xiaoping Zhang

2

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Simi Gunaseelan

3

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Shahriar Pooyan

4

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Olivia Debrah

5

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Michael J Leibowitz

6

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Arnold B Rabson

7

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Stanley Stein

8

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Patrick J Sinko

9

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

publication date

24 April 2006

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

AIDS Research and Therapy

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

12

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Quantitative assessment of the cell penetrating properties of RI-Tat-9: evidence for a cell type-specific barrier at the plasma membrane of epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1481600

7 July 2018

Synthesis of poly(ethylene glycol)-based saquinavir prodrug conjugates and assessment of release and anti-HIV-1 bioactivity using a novel protease inhibition assay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1481600

7 July 2018

CD4 T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1481600

7 July 2018

Pharmacokinetic and biodistribution properties of poly(ethylene glycol)–protein conjugates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1481600

7 July 2018

Effect of pegylation on pharmaceuticals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1481600

7 July 2018

Small HIV-1-Tat peptides inhibit HIV replication in cultured T-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1481600

7 July 2018

Direct evidence that saquinavir is transported by multidrug resistance-associated protein (MRP1) and canalicular multispecific organic anion transporter (MRP2).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1481600

7 July 2018

A randomized trial of simplified maintenance therapy with abacavir, lamivudine, and zidovudine in human immunodeficiency virus infection

1 reference

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Anti-TAR polyamide nucleotide analog conjugated with a membrane-permeating peptide inhibits human immunodeficiency virus type 1 production

1 reference

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Limited patient adherence to highly active antiretroviral therapy for HIV-1 infection in an observational cohort study.

1 reference

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7 July 2018

P-Glycoprotein and transporter MRP1 reduce HIV protease inhibitor uptake in CD4 cells: potential for accelerated viral drug resistance?

1 reference

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7 July 2018

The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters

1 reference

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7 July 2018

Selective CXCR4 antagonism by Tat: implications for in vivo expansion of coreceptor use by HIV-1

1 reference

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7 July 2018

Adherence to protease inhibitor therapy and outcomes in patients with HIV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1481600

7 July 2018

P-glycoprotein, secretory transport, and other barriers to the oral delivery of anti-HIV drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1481600

7 July 2018

Inhibition of CXCR4-dependent HIV-1 infection by extracellular HIV-1 Tat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1481600

7 July 2018

Adherence to protease inhibitors, HIV-1 viral load, and development of drug resistance in an indigent population.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1481600

7 July 2018

Multifaceted activities of the HIV-1 transactivator of transcription, Tat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1481600

7 July 2018

A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1481600

7 July 2018

Translational effects of peptide antagonists of Tat protein of human immunodeficiency virus type 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1481600

7 July 2018

Synthesis and biological properties of novel pyridinioalkanoyl thiolesters (PATE) as anti-HIV-1 agents that target the viral nucleocapsid protein zinc fingers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1481600

7 July 2018

Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1481600

7 July 2018

HIV-protease inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1481600

7 July 2018

A new class of HIV-1 Tat antagonist acting through Tat-TAR inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1481600

7 July 2018

Inhibition of HIV-1 replication by a Tat RNA-binding domain peptide analog.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1481600

7 July 2018

A Small-molecule Inhibitor Directed against the Chemokine Receptor CXCR4 Prevents its Use as an HIV-1 Coreceptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1481600

7 July 2018

Anti-human immunodeficiency virus type 1 activity of an oligocationic compound mediated via gp120 V3 interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1481600

7 July 2018

Viral resistance and the selection of antiretroviral combinations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1481600

7 July 2018

Genetic analysis of the cofactor requirement for human immunodeficiency virus type 1 Tat function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1481600

7 July 2018

Peptides corresponding to a predictive alpha-helical domain of human immunodeficiency virus type 1 gp41 are potent inhibitors of virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1481600

7 July 2018

Increased cellular uptake of the human immunodeficiency virus-1 Tat protein after modification with biotin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1481600

7 July 2018

Recent developments in retro peptides and proteins--an ongoing topochemical exploration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1481600

7 July 2018

Cellular uptake of the tat protein from human immunodeficiency virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1481600

7 July 2018

Mutational analysis of the conserved basic domain of human immunodeficiency virus tat protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1481600

7 July 2018

Structural and functional characterization of human immunodeficiency virus tat protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1481600

7 July 2018

Rational design of peptide-based HIV proteinase inhibitors

1 reference

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The HIV-1 protease as a therapeutic target for AIDS

1 reference

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Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

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Differentiation of gut and hepatic first pass metabolism and secretion of saquinavir in ported rabbits

1 reference

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Efficacy of enfuvirtide in patients infected with drug-resistant HIV-1 in Europe and Australia

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Tat-conjugated synthetic macromolecules facilitate cytoplasmic drug delivery to human ovarian carcinoma cells

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26 October 2018

Pharmacokinetics and delivery of tat and tat-protein conjugates to tissues in vivo

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26 October 2018

The in vitro evaluation of polyethylene glycol esters of hydrocortisone 21-succinate as ocular prodrugs

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12 December 2020

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Investigation of distribution, transport and uptake of anti-HIV drugs to the central nervous system

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https://pubmed.ncbi.nlm.nih.gov/16635263

12 December 2020

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Alteration of the circulating life and antigenic properties of bovine adenosine deaminase in mice by attachment of polyethylene glycol

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https://pubmed.ncbi.nlm.nih.gov/16635263

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Identifiers

10.1186/1742-6405-3-12

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Europe PubMed Central

PubMed publication ID

4 August 2017

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

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