Increased p53 activity does not accelerate telomere-driven ageing (Q34683069)

3 August 2017

title

Increased p53 activity does not accelerate telomere-driven ageing (English)

1 reference

3 August 2017

Manuel Serrano

8

0 references

Maria A Blasco

object named as

María A Blasco

7

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author name string

Isabel García-Cao

1

1 reference

3 August 2017

Marta García-Cao

2

1 reference

3 August 2017

Antonia Tomás-Loba

3

1 reference

3 August 2017

Juan Martín-Caballero

4

1 reference

3 August 2017

Juana M Flores

5

1 reference

3 August 2017

Peter Klatt

6

1 reference

3 August 2017

publication date

31 March 2006

1 reference

3 August 2017

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3 August 2017

volume

7

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3 August 2017

issue

5

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3 August 2017

page(s)

546-552

1 reference

Tumor suppression and normal aging in mice with constitutively high p53 activity

3 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

Increased gene dosage of Ink4a/Arf results in cancer resistance and normal aging.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

Phosphorylation of H2AX at short telomeres in T cells and fibroblasts

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

Long lifespan in worms with long telomeric DNA.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

Modulation of mammalian life span by the short isoform of p53.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

Telomeres, stem cells, senescence, and cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

Replicative senescence and the art of counting

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

A DNA damage checkpoint response in telomere-initiated senescence

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

DNA damage foci at dysfunctional telomeres

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

Telomeres in cancer and aging: lessons from the mouse

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

Aging and genome maintenance: lessons from the mouse?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

Association between telomere length in blood and mortality in people aged 60 years or older

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

Ablation of telomerase and telomere loss leads to cardiac dilatation and heart failure associated with p53 upregulation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

Functional interaction between DNA-PKcs and telomerase in telomere length maintenance

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

"Super p53" mice exhibit enhanced DNA damage response, are tumor resistant and age normally

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

Different telomere damage signaling pathways in human and mouse cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

Mammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

Many ways to telomere dysfunction: in vivo studies using mouse models

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

Protection of mammalian telomeres

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

p53 mutant mice that display early ageing-associated phenotypes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

Switching and signaling at the telomere

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

Induction of senescence by oncogenic Ras.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G-strand overhang

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

Disease states associated with telomerase deficiency appear earlier in mice with short telomeres

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

Essential role of mouse telomerase in highly proliferative organs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

A globin enhancer acts by increasing the proportion of erythrocytes expressing a linked transgene.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

Age-dependent silencing of globin transgenes in the mouse

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

p53 is required for radiation-induced apoptosis in mouse thymocytes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

An apoptotic defect in lens differentiation caused by human p53 is rescued by a mutant allele

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

Temporal and spatial patterns of transgene expression in aging adult mice provide insights about the origins, organization, and differentiation of the intestinal epithelium

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1479549

Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis.

7 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038/SJ.EMBOR.7400667

Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038/SJ.EMBOR.7400667

Telomeres, stem cells, senescence, and cancer

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038/SJ.EMBOR.7400667

Insulators to improve expression of a 3(')IgH LCR-driven reporter gene in transgenic mouse models

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16582880

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Coupling between gamma irradiation, p53 induction and the apoptotic response depends upon cell type in vivo

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16582880

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Wild-type p53 transgenic mice exhibit altered differentiation of the ureteric bud and possess small kidneys

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16582880

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SJ.EMBOR.7400667

1 reference

3 August 2017

1 reference

3 August 2017

1 reference