Nuclear receptor regulation of hepatic function (Q34666809)

3 August 2017

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title

Nuclear receptor regulation of hepatic function (English)

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3 August 2017

Saul J Karpen

1

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3 August 2017

publication date

1 June 2002

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3 August 2017

published in

Journal of Hepatology

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3 August 2017

volume

36

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3 August 2017

issue

6

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3 August 2017

page(s)

832-850

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Nuclear receptor minireview series

3 August 2017

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Refined solution structure of the glucocorticoid receptor DNA-binding domain

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Heterodimeric Complex of RAR and RXR Nuclear Receptor Ligand-Binding Domains: Purification, Crystallization, and Preliminary X-Ray Diffraction Analysis

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Purification and crystallization of the human RXRalpha ligand-binding domain-9-cisRA complex

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Structural basis of RXR-DNA interactions

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The human nuclear xenobiotic receptor PXR: structural determinants of directed promiscuity

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A unified nomenclature system for the nuclear receptor superfamily

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The RXR heterodimers and orphan receptors

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Nuclear receptor that identifies a novel retinoic acid response pathway

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9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

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7 January 2021

Characterization of three RXR genes that mediate the action of 9-cis retinoic acid

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7 January 2021

Docosahexaenoic acid, a ligand for the retinoid X receptor in mouse brain

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7 January 2021

Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers

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7 January 2021

Initial clinical trial of a selective retinoid X receptor ligand, LGD1069

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7 January 2021

Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling

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7 January 2021

Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors

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7 January 2021

Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently

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7 January 2021

Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors

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7 January 2021

Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

A direct repeat in the cellular retinol-binding protein type II gene confers differential regulation by RXR and RAR

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7 January 2021

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

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7 January 2021

The nuclear receptor superfamily: the second decade

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis.

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Atrial-like phenotype is associated with embryonic ventricular failure in retinoid X receptor alpha -/- mice.

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Hepatocyte-specific mutation establishes retinoid X receptor alpha as a heterodimeric integrator of multiple physiological processes in the liver.

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7 January 2021

Selective ablation of retinoid X receptor alpha in hepatocytes impairs their lifespan and regenerative capacity

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

The acute phase response is associated with retinoid X receptor repression in rodent liver

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Steroid hormone receptors and their regulation by phosphorylation

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7 January 2021

Modulating nuclear receptor function: may the phos be with you

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7 January 2021

Hyperphosphorylation of the retinoid X receptor alpha by activated c-Jun NH2-terminal kinases

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7 January 2021

Mitogen-activated protein kinase inhibits 1,25-dihydroxyvitamin D3-dependent signal transduction by phosphorylating human retinoid X receptor alpha

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7 January 2021

Stress pathway activation induces phosphorylation of retinoid X receptor

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7 January 2021

Phosphorylation of retinoid X receptor suppresses its ubiquitination in human hepatocellular carcinoma

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7 January 2021

Modulation of retinoid signalling through NGF-induced nuclear export of NGFI-B

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7 January 2021

The effect of retinoic acid on the re-establishment of differentiated hepatocyte phenotype in primary culture

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7 January 2021

A new orphan member of the nuclear hormone receptor superfamily that interacts with a subset of retinoic acid response elements

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7 January 2021

Differential Transactivation by Two Isoforms of the Orphan Nuclear Hormone Receptor CAR

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7 January 2021

The phenobarbital response enhancer module in the human bilirubin UDP-glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR.

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7 January 2021

Diverse roles of the nuclear orphan receptor CAR in regulating hepatic genes in response to phenobarbital

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Androstane metabolites bind to and deactivate the nuclear receptor CAR-beta

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Role reversal: new insights from new ligands for the xenobiotic receptor CAR.

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

The xenobiotic compound 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene is an agonist ligand for the nuclear receptor CAR

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Phenobarbital response elements of cytochrome P450 genes and nuclear receptors

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR.

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Chemical genomics: functional analysis of orphan nuclear receptors in the regulation of bile acid metabolism

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Phenobarbital-responsive nuclear translocation of the receptor CAR in induction of the CYP2B gene

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Phenobarbital-elicited activation of nuclear receptor CAR in induction of cytochrome P450 genes

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7 January 2021

The peptide near the C terminus regulates receptor CAR nuclear translocation induced by xenochemicals in mouse liver

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7 January 2021

Orphan nuclear receptors: the exotics of xenobiotics.

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7 January 2021

Transcriptional regulation of CYP2C9 gene. Role of glucocorticoid receptor and constitutive androstane receptor

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Effect of phenobarbital on the expression of bile salt and organic anion transporters of rat liver

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Hepatic uptake of bilirubin and its conjugates by the human organic anion transporter SLC21A6

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Bile Flow and Biliary Excretion Rate of Some Organic Anions in Phenobarbital-Pretreated Rats

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7 January 2021

Effects of barbiturates on the hepatic cytochrome P-450 dependent enzyme system and biliary excretion of exogenous organic anions in rats

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7 January 2021

Bile acids: natural ligands for an orphan nuclear receptor

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7 January 2021

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

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7 January 2021

Identification of a nuclear receptor for bile acids

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7 January 2021

Identification of a nuclear receptor that is activated by farnesol metabolites

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Identification of the DNA binding specificity and potential target genes for the farnesoid X-activated receptor

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7 January 2021

The farnesoid X-activated receptor mediates bile acid activation of phospholipid transfer protein gene expression

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7 January 2021

Orphan nuclear receptors as eLiXiRs and FiXeRs of sterol metabolism.

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7 January 2021

Bile acids go nuclear!

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7 January 2021

A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

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7 January 2021

Xol INXS: role of the liver X and the farnesol X receptors

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7 January 2021

"Don't know much bile-ology"

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7 January 2021

Nuclear orphan receptors control cholesterol catabolism.

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7 January 2021

Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

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7 January 2021

Down-regulation of cholesterol 7alpha-hydroxylase (CYP7A1) gene expression by bile acids in primary rat hepatocytes is mediated by the c-Jun N-terminal kinase pathway

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7 January 2021

Bile acid induction of cytokine expression by macrophages correlates with repression of hepatic cholesterol 7alpha-hydroxylase

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7 January 2021

Bile acids modulate the interferon signalling pathway

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor.

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome P450.

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Farnesoid X receptor and bile salts are involved in transcriptional regulation of the gene encoding the human bile salt export pump

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7 January 2021

Expression of the bile salt export pump is maintained after chronic cholestasis in the rat.

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7 January 2021

Adaptive regulation of bile salt transporters in kidney and liver in obstructive cholestasis in the rat

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7 January 2021

Effects of bile acids and steroid/thyroid hormones on the expression of cholesterol 7 alpha-hydroxylase mRNA and the CYP7 gene in HepG2 cells

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7 January 2021

Farnesoid X receptor responds to bile acids and represses cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Regulation of cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription by the liver orphan receptor (LXRalpha).

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Molecular pathogenesis of cholestasis.

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7 January 2021

Endotoxin downregulates rat hepatic ntcp gene expression via decreased activity of critical transcription factors

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Inflammation-induced cholestasis

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7 January 2021

Hepatobiliary transporter expression in percutaneous liver biopsies of patients with cholestatic liver diseases.

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

The orphan nuclear receptor, shp, mediates bile acid-induced inhibition of the rat bile acid transporter, ntcp

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7 January 2021

Dehydroepiandrosterone sulfotransferase gene induction by bile acid activated farnesoid X receptor

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

LXR, a nuclear receptor that defines a distinct retinoid response pathway

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7 January 2021

Liver X receptor (LXR) regulation of the LXRalpha gene in human macrophages

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Selective activation of liver X receptor alpha by 6alpha-hydroxy bile acids and analogs

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Role of LXRs in control of lipogenesis

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Cholesterol and Bile Acid Metabolism Are Impaired in Mice Lacking the Nuclear Oxysterol Receptor LXRα

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRbeta-deficient mice

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Cross-talk between fatty acid and cholesterol metabolism mediated by liver X receptor-alpha

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Induction of human liver X receptor alpha gene expression via an autoregulatory loop mechanism

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Autoregulation of the human liver X receptor alpha promoter

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Nuclear receptors and lipid physiology: opening the X-files

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Control of cholesterol turnover in the mouse

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

The role of orphan nuclear receptors in the regulation of cholesterol homeostasis

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Characterization of the human ABCG1 gene: liver X receptor activates an internal promoter that produces a novel transcript encoding an alternative form of the protein

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter

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7 January 2021

Regulation of gene expression by SREBP and SCAP.

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Sterol upregulation of human CETP expression in vitro and in transgenic mice by an LXR element

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Regulation of lipoprotein lipase by the oxysterol receptors, LXRalpha and LXRbeta.

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

NATURE OF THE HEPATOMEGALIC EFFECT PRODUCED BY ETHYL-CHLOROPHENOXY-ISOBUTYRATE IN THE RAT

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7 January 2021

The peroxisome proliferator activated receptors (PPARS) and their effects on lipid metabolism and adipocyte differentiation

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Peroxisome proliferators and peroxisome proliferator activated receptors (PPARs) as regulators of lipid metabolism

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https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

The peroxisome proliferator-activated receptors at the cross-road of diet and hormonal signalling

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

DNA binding preferences of PPAR alpha/RXR alpha heterodimers

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Human and rat peroxisome proliferator activated receptors (PPARs) demonstrate similar tissue distribution but different responsiveness to PPAR activators

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Peroxisome Proliferator Activated Receptor-α Expression in Human Liver

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

PPAR-gamma: adipogenic regulator and thiazolidinedione receptor

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Peroxisome proliferator-activated receptors in inflammation control

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Recent update on the PPARα-null mouse

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Peroxisomal beta-oxidation and peroxisome proliferator-activated receptor alpha: an adaptive metabolic system

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

PPAR Tissue Distribution and Interactions with Other Hormone-Signaling Pathways

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Expression of the Peroxisome Proliferator-activated Receptor Gene Is Stimulated by Stress and Follows a Diurnal Rhythm

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Peroxisome proliferator-activated receptors, coactivators, and downstream targets

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Induction of the fatty acid transport protein 1 and acyl-CoA synthase genes by dimer-selective rexinoids suggests that the peroxisome proliferator-activated receptor-retinoid X receptor heterodimer is their molecular target

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Fibrate induction of the adrenoleukodystrophy-related gene (ABCD2): promoter analysis and role of the peroxisome proliferator-activated receptor PPARalpha

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Peroxisome proliferator-activated receptor-alpha activation and high-density lipoprotein metabolism

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Characterization of the Adrenoleukodystrophy-Related (ALDR, ABCD2) Gene Promoter: Inductibility by Retinoic Acid and Forskolin

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Fibrates increase human apolipoprotein A-II expression through activation of the peroxisome proliferator-activated receptor

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Binding specificity and modulation of the human ApoCIII promoter activity by heterodimers of ligand-dependent nuclear receptors

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Direct regulatory effect of fatty acids on macrophage lipoprotein lipase: potential role of PPARs

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Fibrates induce mdr2 gene expression and biliary phospholipid secretion in the mouse

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Nonalcoholic steatosis and steatohepatitis. III. Peroxisomal beta-oxidation, PPAR alpha, and steatohepatitis

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Peroxisomal beta-oxidation and steatohepatitis

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

The peroxisome proliferator-activated receptor alpha (PPARalpha) regulates bile acid biosynthesis

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

The effect of peroxisome-proliferator-activated receptor-alpha on the activity of the cholesterol 7 alpha-hydroxylase gene

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

The orphan nuclear hormone receptor LXR alpha interacts with the peroxisome proliferator-activated receptor and inhibits peroxisome proliferator signaling

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Peroxisome proliferators and fatty acids negatively regulate liver X receptor-mediated activity and sterol biosynthesis

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

An Orphan Nuclear Receptor Activated by Pregnanes Defines a Novel Steroid Signaling Pathway

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

SXR, a novel steroid and xenobiotic-sensing nuclear receptor

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Pregnane X receptor: molecular basis for species differences in CYP3A induction by xenobiotics

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Orphan receptor promiscuity in the induction of cytochromes p450 by xenobiotics

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

The PXR ligand-binding domain: how to be picky and promiscuous at the same time.

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Bisphenol-A, an environmental estrogen, activates the human orphan nuclear receptor, steroid and xenobiotic receptor-mediated transcription

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Peptide mimetic HIV protease inhibitors are ligands for the orphan receptor SXR.

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Regulation of cyp3a gene transcription by the pregnane x receptor

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Use of the nuclear receptor PXR to predict drug interactions

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Rat pregnane X receptor: molecular cloning, tissue distribution, and xenobiotic regulation

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

The expression of pregnane X receptor and its target gene, cytochrome P450 3A1, in perinatal mouse

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Humanized xenobiotic response in mice expressing nuclear receptor SXR.

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Dexamethasone induces pregnane X receptor and retinoid X receptor-alpha expression in human hepatocytes: synergistic increase of CYP3A4 induction by pregnane X receptor activators

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Influence of redox-active compounds and PXR-activators on human MRP1 and MRP2 gene expression

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

The effect of rifampin treatment on intestinal expression of human MRP transporters

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Identification of a receptor for the morphogen retinoic acid

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

A human retinoic acid receptor which belongs to the family of nuclear receptors

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Identification of a second human retinoic acid receptor

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

A third human retinoic acid receptor, hRAR-gamma

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Cloning of murine alpha and beta retinoic acid receptors and a novel receptor gamma predominantly expressed in skin

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Nonsteroid nuclear receptors: what are genetic studies telling us about their role in real life?

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Limited specificity and large overlap of the functions of the mouse RARγ1 and RARγ2 isoforms

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Genetic analysis of RXR alpha developmental function: convergence of RXR and RAR signaling pathways in heart and eye morphogenesis

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Serine 157, a retinoic acid receptor alpha residue phosphorylated by protein kinase C in vitro, is involved in RXR.RARalpha heterodimerization and transcriptional activity

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

All-trans-retinoic acid inhibits Jun N-terminal kinase by increasing dual-specificity phosphatase activity

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Protein phosphatases 1 and 2A regulate the transcriptional and DNA binding activities of retinoic acid receptors

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Retinoic acid receptor gamma: specific immunodetection and phosphorylation

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Immunodetection of multiple species of retinoic acid receptor alpha: evidence for phosphorylation

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Dimerization with retinoid X receptors and phosphorylation modulate the retinoic acid-induced degradation of retinoic acid receptors alpha and gamma through the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Positive and negative regulations of albumin gene expression by retinoids in human hepatoma cell lines

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

RXR-mediated regulation of the alpha-fetoprotein gene through an upstream element

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Transactivation and repression of the alpha-fetoprotein gene promoter by retinoid X receptor and chicken ovalbumin upstream promoter transcription factor

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

The 5' sequence of human factor XII gene contains transcription regulatory elements typical of liver specific, estrogen-modulated genes.

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

The opposing effects of retinoic acid and phorbol esters converge to a common response element in the promoter of the rat cholesterol 7 alpha-hydroxylase gene (CYP7A).

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Interleukin-1beta suppresses retinoid transactivation of two hepatic transporter genes involved in bile formation

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

An orphan nuclear hormone receptor that lacks a DNA binding domain and heterodimerizes with other receptors

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

The orphan nuclear receptor SHP inhibits agonist-dependent transcriptional activity of estrogen receptors ERalpha and ERbeta

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Structure and expression of the orphan nuclear receptor SHP gene

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Dual mechanisms for repression of the monomeric orphan receptor liver receptor homologous protein-1 by the orphan small heterodimer partner

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

The orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: two mechanisms for repression

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Induction of short heterodimer partner 1 precedes downregulation of Ntcp in bile duct-ligated mice

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

The orphan nuclear receptor small heterodimer partner as a novel coregulator of nuclear factor-kappa b in oxidized low density lipoprotein-treated macrophage cell line RAW 264.7.

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

Small heterodimer partner, an orphan nuclear receptor, augments peroxisome proliferator-activated receptor gamma transactivation

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

NUREBASE: database of nuclear hormone receptors

1 reference

https://api.crossref.org/works/10.1016/S0168-8278(02)00129-0

7 January 2021

10.1016/S0168-8278(02)00129-0

Identifiers

DOI

1 reference

3 August 2017

1 reference