A critical analysis of the role of growth hormone and IGF-1 in aging and lifespan. (Q34666727)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12044358 AND SRC:MED&resulttype=core&format=json

9 November 2019

review article

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title

A critical analysis of the role of growth hormone and IGF-1 in aging and lifespan (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12044358 AND SRC:MED&resulttype=core&format=json

9 November 2019

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3

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9 November 2019

author name string

Christy S Carter

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12044358 AND SRC:MED&resulttype=core&format=json

9 November 2019

Melinda M Ramsey

series ordinal

2

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9 November 2019

publication date

1 June 2002

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9 November 2019

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9 November 2019

volume

18

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9 November 2019

issue

6

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9 November 2019

page(s)

295-301

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Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor

9 November 2019

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A conserved regulatory system for aging

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Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling

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Cell nonautonomy of C. elegans daf-2 function in the regulation of diapause and life span

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Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein

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Metallothionein-Human GH Fusion Genes Stimulate Growth of Mice

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Inherited Ateliotic Dwarfism in Mice: Characteristics of the mutation, little, on Chromosome 6

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Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production

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DWARF, A NEW MENDELIAN RECESSIVE CHARACTER OF THE HOUSE MOUSE.

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Pituitary lineage determination by the Prophet of Pit-1 homeodomain factor defective in Ames dwarfism

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Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1.

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Does growth hormone prevent or accelerate aging?

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Effects of growth hormone on hypothalamic catalase and Cu/Zn superoxide dismutase

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Growth hormone treatment increases transmural colonic growth in GH-deficient dwarf rats

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Regulation of postnatal intestinal maturation by growth hormone: studies in rats with isolated growth hormone deficiency

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The retardation of aging in mice by dietary restriction: longevity, cancer, immunity and lifetime energy intake

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Reduced levels of thyroid hormones, insulin, and glucose, and lower body core temperature in the growth hormone receptor/binding protein knockout mouse.

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Extending the lifespan of long-lived mice

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Kleemeier award lecture: are there genes for aging?

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The role of the insulin-like growth factor system in human cancer

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Overexpression of the human insulinlike growth factor I receptor promotes ligand-dependent neoplastic transformation

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Regulation of breast cancer growth by insulin-like growth factors

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IGF-I and IGF-II expression in human breast cancer xenografts: relationship to hormone independence

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Processing of insulin-like growth factor-II (IGF-II) by human breast cancer cells

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Characterization of insulin-like growth factor I receptors and growth effects in human lung cancer cell lines

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Expression of insulin-like growth factor receptors I and II in normal human lung and in lung cancer

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Blockade of the insulin-like growth-factor-I receptor inhibits growth of human colorectal cancer cells: evidence of a functional IGF-II-mediated autocrine loop

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Human osteosarcoma (U-2 OS) cells express both insulin-like growth factor-I (IGF-I) receptors and insulin-like growth factor-II/mannose-6-phosphate (IGF-II/M6P) receptors and synthesize IGF-II: autocrine growth stimulation by IGF-II via the IGF-I re

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Autonomous growth of a human neuroblastoma cell line is mediated by insulin-like growth factor II.

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Type 1 IGF receptor in human breast diseases

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Abscence of sleep-related growth hormone peaks in aged normal subjects and in acromegaly

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7 January 2021

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Impaired growth hormone secretion in the adult population: relation to age and adiposity

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Decreased pulsatile release of growth hormone in old male rats

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Effect of rat age on serum levels of growth hormone and somatomedins

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Chronic [D-Ala2]-growth hormone-releasing hormone administration attenuates age-related deficits in spatial memory

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Growth hormone increases regional coronary blood flow and capillary density in aged rats

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Pleiotropic effects of growth hormone and insulin-like growth factor (IGF)-1 on biological aging: inferences from moderate caloric-restricted animals

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Insulin-like growth factor-1 ameliorates age-related behavioral deficits.

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A test of evolutionary theories of senescence

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Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12044358 AND SRC:MED&resulttype=core&format=json

9 November 2019

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