The configuration of the immunoglobulin genes in B cell chronic lymphocytic leukemia (Q34662848)

3 August 2017

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title

The configuration of the immunoglobulin genes in B cell chronic lymphocytic leukemia (English)

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3 August 2017

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Dyer MJ

1

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3 August 2017

Oscier DG

series ordinal

2

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3 August 2017

publication date

1 June 2002

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3 August 2017

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3 August 2017

volume

16

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3 August 2017

issue

6

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3 August 2017

page(s)

973-984

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Genomic aberrations and survival in chronic lymphocytic leukemia

3 August 2017

cites work

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

https://api.crossref.org/works/10.1038/SJ.LEU.2402528

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7 January 2021

Nucleotide sequence, transcription map, and mutation analysis of the 13q14 chromosomal region deleted in B-cell chronic lymphocytic leukemia

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7 January 2021

B-cell neoplasia associated gene with multiple splicing (BCMS): the candidate B-CLL gene on 13q14 comprises more than 560 kb covering all critical regions

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7 January 2021

Cancer epigenetics comes of age

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7 January 2021

C(m)C(a/t)GG methylation: a new epigenetic mark in mammalian DNA?

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7 January 2021

Cytogenetic, fluorescence in situ hybridisation, and clinical evaluation of translocations with concomitant deletion at 13q14 in chronic lymphocytic leukaemia

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7 January 2021

Mechanisms of chromosomal translocations in B cell lymphomas

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7 January 2021

Chromosome translocations in multiple myeloma

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7 January 2021

IRTA1 and IRTA2, novel immunoglobulin superfamily receptors expressed in B cells and involved in chromosome 1q21 abnormalities in B cell malignancy

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Cyclin D3 at 6p21 is dysregulated by recurrent chromosomal translocations to immunoglobulin loci in multiple myeloma.

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Cyclin D3 is a target gene of t(6;14)(p21.1;q32.3) of mature B-cell malignancies

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

The BCL11 gene family: involvement of BCL11A in lymphoid malignancies

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Complex layers of genetic alteration in the generation of antibody diversity

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death.

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Immunoglobulin heavy chain enhancer is located near or in an initiation zone of chromosomal DNA replication

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Dependence of enhancer-mediated transcription of the immunoglobulin mu gene on nuclear matrix attachment regions

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Regulation of matrix attachment region-dependent, lymphocyte-restricted transcription through differential localization within promyelocytic leukemia nuclear bodies

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Nonequivalent nuclear location of immunoglobulin alleles in B lymphocytes.

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Novel control motif cluster in the IgH delta-gamma 3 interval exhibits B cell-specific enhancer function in early development

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Memory B-cell persistence is independent of persisting immunizing antigen.

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Signals sustaining human immunoglobulin V gene hypermutation in isolated germinal centre B cells

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Signals that initiate somatic hypermutation of B cells in vitro

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Within germinal centers, isotype switching of immunoglobulin genes occurs after the onset of somatic mutation

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Linking class-switch recombination with somatic hypermutation

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Indirect and direct evidence for DNA double-strand breaks in hypermutating immunoglobulin genes

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Lack of allelic exclusion in B cell chronic lymphocytic leukemia

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Demethylation and the establishment of kappa allelic exclusion

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Somatic hypermutation in normal and transformed human B cells

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Insight into the origin and clonal history of B-cell tumors as revealed by analysis of immunoglobulin variable region genes

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Clinical relevance of immunoglobulin mutation analysis

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

B cells of chronic lymphatic leukemia express V genes in unmutated form

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

The pathogenesis of chronic lymphocytic leukemia: analysis of the antibody repertoire

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

CD38 expression is a poor predictor for VH gene mutational status and prognosis in chronic lymphocytic leukemia

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

CD38 expression and immunoglobulin variable region mutations are independent prognostic variables in chronic lymphocytic leukemia, but CD38 expression may vary during the course of the disease.

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

CD38 expression and Ig VH gene mutation in B-cell chronic lymphocytic leukemia

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

p53 dysfunction in B-cell chronic lymphocytic leukemia: inactivation of ATM as an alternative to TP53 mutation

1 reference

https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

The human immunoglobulin VH repertoire

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Somatic generation of antigen-receptor diversity: a reprise

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Analysis of the targeting of the hypermutational machinery and the impact of subsequent selection on the distribution of nucleotide changes in human VHDJH rearrangements

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

1 reference

https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Immunoglobulin VH gene expression in human aging

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Chronic lymphocytic leukemia B cells express restricted sets of mutated and unmutated antigen receptors.

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Normal B cells express 51p1-encoded Ig heavy chains that are distinct from those expressed by chronic lymphocytic leukemia B cells

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

The CDR1 sequences of a major proportion of human germline Ig VH genes are inherently susceptible to amino acid replacement

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

The inference of antigen selection on Ig genes

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory B cells.

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Examples of in vivo isotype class switching in IgM chronic lymphocytic leukemia B cells.

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Aberrant rearrangements of the immunoglobulin heavy chain switch region in chronic B-cell leukemia

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Anomalous rearrangements of the immunoglobulin heavy chain genes in human leukemias support the loop-out mechanism of class switch

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Identification of three subgroups of B cell chronic lymphocytic leukemia based upon mutations of BCL-6 and IgV genes

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Somatic hypermutation of immunoglobulin and non-immunoglobulin genes

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

1 reference

https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

The role of Ig beta in precursor B cell transition and allelic exclusion

1 reference

https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Widespread B29 (CD79b) gene defects and loss of expression in chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Aberrant B cell receptor signaling from B29 (Igbeta, CD79b) gene mutations of chronic lymphocytic leukemia B cells

1 reference

https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

CmC(A/T)GG DNA methylation in mature B cell lymphoma gene silencing

1 reference

https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

A new recurrent and specific cryptic translocation, t(5;14)(q35;q32), is associated with expression of the Hox11L2 gene in T acute lymphoblastic leukemia.

1 reference

https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

The anti-apoptosis function of Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry

1 reference

https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Refinement of theBCL2/immunoglobulin heavy chain fusion gene in t(14;18)(q32;q21) by polymerase chain reaction amplification for long targets

1 reference

https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Characterisation of BCL2-JH rearrangements in follicular lymphoma: PCR detection of 3' BCL2 breakpoints and evidence of a new cluster

1 reference

https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Variant translocation of the bcl-2 gene to immunoglobulin lambda light chain gene in chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Preferential linkage of bcl-2 to immunoglobulin light chain gene in chronic lymphocytic leukemia

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

CD5 expression in human B-cell populations

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Cloning of the chromosome translocation breakpoint junction of the t(14;19) in chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

t(14;19)/BCL3 rearrangements in lymphoproliferative disorders: a review of 23 cases

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Candidate proto-oncogene bcl-3 encodes a subunit-specific inhibitor of transcription factor NF-kappa B

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Bcl-3 expression promotes cell survival following interleukin-4 deprivation and is controlled by AP1 and AP1-like transcription factors

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

The putative oncoprotein Bcl-3 induces cyclin D1 to stimulate G(1) transition

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Lymphadenopathy, splenomegaly, and altered immunoglobulin production in BCL3 transgenic mice.

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Evi9 encodes a novel zinc finger protein that physically interacts with BCL6, a known human B-cell proto-oncogene product

1 reference

https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Human EVI9, a homologue of the mouse myeloid leukemia gene, is expressed in the hematopoietic progenitors and down-regulated during myeloid differentiation of HL60 cells

1 reference

https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Recurrent involvement of the REL and BCL11A loci in classical Hodgkin lymphoma.

1 reference

https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Lack of somatic hypermutation of IG V(H) genes in lymphoid malignancies with t(2;14)(p13;q32) translocation involving the BCL11A gene

1 reference

https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Cyclin D2 promoter disrupted by t(12;22)(p13;q11.2) during transformation of chronic lymphocytic leukaemia to non-Hodgkin's lymphoma

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Cyclin D2 is essential for BCR-mediated proliferation and CD5 B cell development

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Vav is required for cyclin D2 induction and proliferation of mouse B lymphocytes activated via the antigen Receptor.

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Survival of leukemic B cells promoted by engagement of the antigen receptor

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Follicular lymphoma with a novel t(14;18) breakpoint involving the immunoglobulin heavy chain switch mu region indicates an origin from germinal center B cells

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https://api.crossref.org/works/10.1038/SJ.LEU.2402528

7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2402528

1 reference

Dimensions Publication ID

3 August 2017

1047272174

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