BRCA2: a universal recombinase regulator. (Q34655484)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18066084 AND SRC:MED&resulttype=core&format=json

29 December 2019

review article

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title

BRCA2: a universal recombinase regulator (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18066084 AND SRC:MED&resulttype=core&format=json

29 December 2019

1

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29 December 2019

Stephen C. West

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18066084 AND SRC:MED&resulttype=core&format=json

29 December 2019

author name string

Thorslund T

series ordinal

1

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3 August 2017

West SC

series ordinal

2

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3 August 2017

language of work or name

English

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publication date

1 December 2007

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29 December 2019

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29 December 2019

volume

26

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29 December 2019

issue

56

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29 December 2019

page(s)

7720-7730

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Distribution of the Rad51 recombinase in human and mouse spermatocytes

29 December 2019

cites work

1 reference

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Lethality induced by a single site-specific double-strand break in a dispensable yeast plasmid

21 January 2018

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Expression of BRC repeats in breast cancer cells disrupts the BRCA2-Rad51 complex and leads to radiation hypersensitivity and loss of G(2)/M checkpoint control

21 January 2018

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Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells

21 January 2018

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The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment

21 January 2018

1 reference

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Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation

21 January 2018

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Crystal structure of a Rad51 filament

21 January 2018

1 reference

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Role of BRCA2 in control of the RAD51 recombination and DNA repair protein.

21 January 2018

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Deletion of Brca2 exon 27 causes hypersensitivity to DNA crosslinks, chromosomal instability, and reduced life span in mice.

21 January 2018

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Interaction between Arabidopsis Brca2 and its partners Rad51, Dmc1, and Dss1.

21 January 2018

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CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair

21 January 2018

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Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2.

21 January 2018

1 reference

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BRCA2 BRC motifs bind RAD51-DNA filaments

21 January 2018

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Nuclear foci of mammalian Rad51 recombination protein in somatic cells after DNA damage and its localization in synaptonemal complexes

21 January 2018

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Genome maintenance mechanisms for preventing cancer

21 January 2018

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Structural basis for octameric ring formation and DNA interaction of the human homologous-pairing protein Dmc1.

21 January 2018

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BRCA2 homolog required for proficiency in DNA repair, recombination, and genome stability in Ustilago maydis.

21 January 2018

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A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53

21 January 2018

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Instability and decay of the primary structure of DNA

21 January 2018

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Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos

21 January 2018

1 reference

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The BRCA2 gene product functionally interacts with p53 and RAD51

21 January 2018

1 reference

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RAD-51-dependent and -independent roles of a Caenorhabditis elegans BRCA2-related protein during DNA double-strand break repair

21 January 2018

1 reference

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RAB22 and RAB163/mouse BRCA2: proteins that specifically interact with the RAD51 protein

21 January 2018

1 reference

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BRCA2 is required for homology-directed repair of chromosomal breaks

21 January 2018

1 reference

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Clarifying the mechanics of DNA strand exchange in meiotic recombination

21 January 2018

1 reference

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Involvement of Brca2 in DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210870

Insights into DNA recombination from the structure of a RAD51-BRCA2 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210870

Stabilization of RAD-51-DNA filaments via an interaction domain in Caenorhabditis elegans BRCA2

21 January 2018

1 reference

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Meiotic prophase arrest with failure of chromosome synapsis in mice deficient for Dmc1, a germline-specific RecA homolog

21 January 2018

1 reference

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Nuclear foci of mammalian recombination proteins are located at single-stranded DNA regions formed after DNA damage

21 January 2018

1 reference

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Suppression of the DNA repair defects of BRCA2-deficient cells with heterologous protein fusions

21 January 2018

1 reference

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Association of BRCA1 with Rad51 in mitotic and meiotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210870

Human meiotic recombinase Dmc1 promotes ATP-dependent homologous DNA strand exchange.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210870

Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210870

BRCA2 deficiency in mice leads to meiotic impairment and infertility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210870

Full-length archaeal Rad51 structure and mutants: mechanisms for RAD51 assembly and control by BRCA2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210870

Tid1/Rdh54 promotes colocalization of rad51 and dmc1 during meiotic recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210870

A region of human BRCA2 containing multiple BRC repeats promotes RAD51-mediated strand exchange

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210870

Brca2 is involved in meiosis in Arabidopsis thaliana as suggested by its interaction with Dmc1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210870

Mechanism of homologous recombination: mediators and helicases take on regulatory functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210870

Brca2 is required for embryonic cellular proliferation in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210870

Hyper-resistance of meiotic cells to radiation due to a strong expression of a single recA-like gene in Caenorhabditis elegans

21 January 2018

1 reference

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RAD51 localization and activation following DNA damage

21 January 2018

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RAD51 and DMC1 form mixed complexes associated with mouse meiotic chromosome cores and synaptonemal complexes

21 January 2018

1 reference

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Interactions between human BRCA2 protein and the meiosis-specific recombinase DMC1

21 January 2018

1 reference

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Targeted disruption of the Rad51 gene leads to lethality in embryonic mice

21 January 2018

1 reference

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Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences

21 January 2018

1 reference

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Molecular views of recombination proteins and their control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210870

RAD51 Interacts with the Evolutionarily Conserved BRC Motifs in the Human Breast Cancer Susceptibility Gene brca2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210870

Identification of the breast cancer susceptibility gene BRCA2

21 January 2018

1 reference

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The BRCA2 homologue Brh2 nucleates RAD51 filament formation at a dsDNA-ssDNA junction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210870

BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210870

The mouse RecA-like gene Dmc1 is required for homologous chromosome synapsis during meiosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210870

Homozygous germ line mutation in exon 27 of murine Brca2 disrupts the Fancd2-Brca2 pathway in the homologous recombination-mediated DNA interstrand cross-links' repair but does not affect meiosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210870

7 January 2021

Purification and characterization of the human Rad51 protein, an analogue of E. coli RecA

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210870

7 January 2021

Interaction with the BRCA2 C terminus protects RAD51-DNA filaments from disassembly by BRC repeats

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210870

7 January 2021

Conserved domains in the chicken homologue of BRCA2

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210870

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210870

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18066084 AND SRC:MED&resulttype=core&format=json

Dimensions Publication ID

29 December 2019

1030478210

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Fatcat ID

release_jjkfrjsgvnfllmbctwf2hism3i

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Fatcat

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24 November 2022

mapped directly with Wikidata item

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