Impact of the 3D microenvironment on phenotype, gene expression, and EGFR inhibition of colorectal cancer cell lines (Q34651865)

3 August 2017

title

Impact of the 3D microenvironment on phenotype, gene expression, and EGFR inhibition of colorectal cancer cell lines (English)

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3 August 2017

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Anna C Luca

1

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3 August 2017

Sabrina Mersch

2

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3 August 2017

René Deenen

3

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3 August 2017

Stephan Schmidt

4

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3 August 2017

Isabelle Messner

5

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3 August 2017

Karl-Ludwig Schäfer

6

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3 August 2017

Stephan E Baldus

7

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3 August 2017

Wolfgang Huckenbeck

8

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3 August 2017

Roland P Piekorz

9

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3 August 2017

Wolfram T Knoefel

10

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3 August 2017

Andreas Krieg

11

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3 August 2017

Nikolas H Stoecklein

12

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3 August 2017

language of work or name

English

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publication date

26 March 2013

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3 August 2017

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3 August 2017

volume

8

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3 August 2017

issue

3

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3 August 2017

page(s)

e59689

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Creative Commons Attribution 4.0 International

3 August 2017

copyright license

start time

26 March 2013

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Three-dimensional overlay culture models of human breast cancer reveal a critical sensitivity to mitogen-activated protein kinase kinase inhibitors

7 July 2018

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7 July 2018

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7 July 2018

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HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment

7 July 2018

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Advancing science and technology via 3D culture on basement membrane matrix

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Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer

7 July 2018

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The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression.

7 July 2018

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Glycosylation is crucial for stability of tumour and cancer stem cell antigen EpCAM.

7 July 2018

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Three-dimensional extracellular matrix culture models of EGFR signalling and drug response

7 July 2018

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7 July 2018

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Microenvironmental regulators of tissue structure and function also regulate tumor induction and progression: the role of extracellular matrix and its degrading enzymes

7 July 2018

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Variant glycosylation: an underappreciated regulatory mechanism for beta1 integrins

7 July 2018

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7 July 2018

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The organizing principle: microenvironmental influences in the normal and malignant breast

7 July 2018

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beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium

7 July 2018

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

7 July 2018

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Human cancer cell lines: fact and fantasy

7 July 2018

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7 July 2018

Basal lamina assembly

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7 July 2018

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7 July 2018

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Laminin forms an independent network in basement membranes

7 July 2018

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Integrins: versatility, modulation, and signaling in cell adhesion

7 July 2018

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Endothelial cells interact with the core protein of basement membrane perlecan through beta 1 and beta 3 integrins: an adhesion modulated by glycosaminoglycan

7 July 2018

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Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3608563

Comparison of 3D and 2D tumor models reveals enhanced HER2 activation in 3D associated with an increased response to trastuzumab.

7 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0059689

Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0059689

Prevalence and heterogeneity of KRAS, BRAF, and PIK3CA mutations in primary colorectal adenocarcinomas and their corresponding metastases

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/23555746

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Nidogen mediates the formation of ternary complexes of basement membrane components

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23555746

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0059689

1 reference

3 August 2017

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3 August 2017

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