Cartilage-specific over-expression of CCN family member 2/connective tissue growth factor (CCN2/CTGF) stimulates insulin-like growth factor expression and bone growth (Q34650896)

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English	Cartilage-specific over-expression of CCN family member 2/connective tissue growth factor (CCN2/CTGF) stimulates insulin-like growth factor expression and bone growth	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

3 August 2017

Cartilage-specific over-expression of CCN family member 2/connective tissue growth factor (CCN2/CTGF) stimulates insulin-like growth factor expression and bone growth (English)

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Europe PubMed Central

PubMed publication ID

3 August 2017

connective tissue

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based on heuristic

inferred from title

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based on heuristic

inferred from title

Takashi Yamashiro

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Takashi Yamashiro

6

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author name string

Nao Tomita

1

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Europe PubMed Central

PubMed publication ID

3 August 2017

Takako Hattori

2

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Europe PubMed Central

PubMed publication ID

3 August 2017

Shinsuke Itoh

3

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Europe PubMed Central

PubMed publication ID

3 August 2017

Eriko Aoyama

4

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Europe PubMed Central

PubMed publication ID

3 August 2017

Mayumi Yao

5

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Europe PubMed Central

PubMed publication ID

3 August 2017

Masaharu Takigawa

7

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Europe PubMed Central

PubMed publication ID

3 August 2017

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publication date

28 March 2013

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Europe PubMed Central

PubMed publication ID

3 August 2017

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Europe PubMed Central

PubMed publication ID

3 August 2017

8

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Europe PubMed Central

PubMed publication ID

3 August 2017

3

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Europe PubMed Central

PubMed publication ID

3 August 2017

e59226

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Europe PubMed Central

PubMed publication ID

3 August 2017

copyright license

Creative Commons Attribution 4.0 International

28 March 2013

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April 2022 Public Data File from Crossref

copyright status

0 references

Transcriptional regulation of chondrogenesis by coactivator Tip60 via chromatin association with Sox9 and Sox5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610707

7 July 2018

Effects of insulin-like growth factor binding proteins in bone -- a matter of cell and site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610707

7 July 2018

Role of CCN2/CTGF/Hcs24 in bone growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610707

7 July 2018

The role of connective tissue growth factor in skeletal growth and development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610707

7 July 2018

Interactions between PIAS proteins and SOX9 result in an increase in the cellular concentrations of SOX9.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610707

7 July 2018

Constitutive activation of MKK6 in chondrocytes of transgenic mice inhibits proliferation and delays endochondral bone formation

1 reference

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7 July 2018

Individual domains of connective tissue growth factor regulate fibroblast proliferation and myofibroblast differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610707

7 July 2018

Constitutive activation of MEK1 in chondrocytes causes Stat1-independent achondroplasia-like dwarfism and rescues the Fgfr3-deficient mouse phenotype

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7 July 2018

Connective tissue growth factor (CCN2) induces adhesion of rat activated hepatic stellate cells by binding of its C-terminal domain to integrin alpha(v)beta(3) and heparan sulfate proteoglycan

1 reference

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7 July 2018

The CCN family: a new stimulus package

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610707

7 July 2018

Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610707

7 July 2018

Role of CTGF/HCS24/ecogenin in skeletal growth control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610707

7 July 2018

Matrix metalloproteinases cleave connective tissue growth factor and reactivate angiogenic activity of vascular endothelial growth factor 165

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610707

7 July 2018

The transcription factors L-Sox5 and Sox6 are essential for cartilage formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610707

7 July 2018

Overexpression of connective tissue growth factor/hypertrophic chondrocyte-specific gene product 24 decreases bone density in adult mice and induces dwarfism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610707

7 July 2018

The angiogenic factors Cyr61 and connective tissue growth factor induce adhesive signaling in primary human skin fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610707

7 July 2018

Effects of CTGF/Hcs24, a hypertrophic chondrocyte-specific gene product, on the proliferation and differentiation of osteoblastic cells in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610707

7 July 2018

Effects of CTGF/Hcs24, a product of a hypertrophic chondrocyte-specific gene, on the proliferation and differentiation of chondrocytes in culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610707

7 July 2018

Sox9 is required for cartilage formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610707

7 July 2018

Binding properties and distribution of insulin-like growth factor binding protein-related protein 3 (IGFBP-rP3/NovH), an additional member of the IGFBP Superfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610707

7 July 2018

Fisp12/mouse connective tissue growth factor mediates endothelial cell adhesion and migration through integrin alphavbeta3, promotes endothelial cell survival, and induces angiogenesis in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610707

7 July 2018

Inhibition of endogenous expression of connective tissue growth factor by its antisense oligonucleotide and antisense RNA suppresses proliferation and migration of vascular endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610707

7 July 2018

Isolation and characterization of a rheumatoid arthritis-specific antigen (RA-A47) from a human chondrocytic cell line (HCS-2/8)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610707

7 July 2018

Insulin-like growth factors I and II are autocrine factors in stimulating proteoglycan synthesis, a marker of differentiated chondrocytes, acting through their respective receptors on a clonal human chondrosarcoma-derived chondrocyte cell line, HCS-

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610707

7 July 2018

Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610707

7 July 2018

Cloning of a mRNA preferentially expressed in chondrocytes by differential display-PCR from a human chondrocytic cell line that is identical with connective tissue growth factor (CTGF) mRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610707

7 July 2018

SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610707

7 July 2018

The modular architecture of a new family of growth regulators related to connective tissue growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610707

7 July 2018

Somatomedin-C/insulin-like growth factor-I and insulin-like growth factor-II mRNAs in rat fetal and adult tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610707

7 July 2018

Histopathology associated with elevated levels of growth hormone and insulin-like growth factor I in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610707

7 July 2018

Renal connective tissue growth factor induction in experimental diabetes is prevented by aminoguanidine

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0059226

21 January 2018

Developmental patterns of insulin-like growth factor-I and -II synthesis and regulation in rat fibroblasts

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0059226

21 January 2018

Expression of connective tissue growth factor in bone: its role in osteoblast proliferation and differentiation in vitro and bone formation in vivo

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0059226

21 January 2018

Characterization of the antibody response in mice with type II collagen–induced arthritis, using monoclonal anti–type II collagen antibodies

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0059226

21 January 2018

CTGF/Hcs24, a hypertrophic chondrocyte-specific gene product, stimulates proliferation and differentiation, but not hypertrophy of cultured articular chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23555635

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CTGF/Hcs24, hypertrophic chondrocyte-specific gene product, interacts with perlecan in regulating the proliferation and differentiation of chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23555635

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clonal proliferation and cell density of chondrocytes isolated from human fetal epiphyseal, human adult articular and nasal septal cartilage. Influence of hormones and growth factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/23555635

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type X collagen synthesis in human osteoarthritic cartilage. Indication of chondrocyte hypertrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23555635

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of primary cultures of chondrocytes from type II collagen/beta-galactosidase transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23555635

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin‐like growth factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/23555635

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Connective tissue growth factor induces the proliferation, migration, and tube formation of vascular endothelial cells in vitro, and angiogenesis in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/23555635

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical analysis of type-X-collagen expression in osteoarthritis of the hip joint

1 reference

https://pubmed.ncbi.nlm.nih.gov/23555635

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CCN family 2/connective tissue growth factor (CCN2/CTGF) stimulates proliferation and differentiation of auricular chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23555635

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0059226

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

2013PLoSO...859226T

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

ResearchGate publication ID

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