The N-terminal CEBPA mutant in acute myeloid leukemia impairs CXCR4 expression (Q34649120)

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16 February 2020

title

The N-terminal CEBPA mutant in acute myeloid leukemia impairs CXCR4 expression (English)

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acute myeloid leukemia

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1

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Hsin-An Hou

2

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Wen-Chien Chou

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Jih-Luh Tang

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Ming Yao

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16 February 2020

Tien Hwei-fang

15

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3

Yin-Kai Chen

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Mei-Hsuan Tseng

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Chi-Fei Huang

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Chia-Wen Liu

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author name string

Li-Yu Li

4

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16 February 2020

Po-Hsuen Chen

5

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Fen-Yu Lee

8

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Ming-Chih Liu

9

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Chieh-Yu Liu

12

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publication date

5 September 2014

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16 February 2020

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16 February 2020

volume

99

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issue

12

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page(s)

1799-1807

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BMS-936564/MDX-1338: a fully human anti-CXCR4 antibody induces apoptosis in vitro and shows antitumor activity in vivo in hematologic malignancies

16 February 2020

cites work

1 reference

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A phase 1/2 study of chemosensitization with the CXCR4 antagonist plerixafor in relapsed or refractory acute myeloid leukemia

7 July 2018

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TET2 mutation is an unfavorable prognostic factor in acute myeloid leukemia patients with intermediate-risk cytogenetics

7 July 2018

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Leukemia Stem Cells and Microenvironment: Biology and Therapeutic Targeting

7 July 2018

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CXCL12 (SDF-1)/CXCR4 pathway in cancer

7 July 2018

1 reference

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Acute myeloid leukemia with biallelic CEBPA gene mutations and normal karyotype represents a distinct genetic entity associated with a favorable clinical outcome

7 July 2018

1 reference

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Complexity of CEBPA dysregulation in human acute myeloid leukemia

7 July 2018

1 reference

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Reply to 'Heterogeneity within AML with CEBPA mutations; only CEBPA double mutations, but not single CEBPA mutations are associated with favorable prognosis'.

7 July 2018

1 reference

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Heterogeneity within AML with CEBPA mutations; only CEBPA double mutations, but not single CEBPA mutations are associated with favourable prognosis

7 July 2018

1 reference

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Dysregulation of the C/EBPalpha differentiation pathway in human cancer

7 July 2018

1 reference

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Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100.

7 July 2018

1 reference

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Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML.

7 July 2018

1 reference

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The bone marrow microenvironment as a tumor sanctuary and contributor to drug resistance

7 July 2018

1 reference

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The CXCR4 chemokine receptor in acute and chronic leukaemia: a marrow homing receptor and potential therapeutic target

7 July 2018

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Transcription factors in myeloid development: balancing differentiation with transformation.

7 July 2018

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Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype

7 July 2018

1 reference

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CXCR4 regulates migration and development of human acute myelogenous leukemia stem cells in transplanted NOD/SCID mice

7 July 2018

1 reference

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C/EBPalphap30, a myeloid leukemia oncoprotein, limits G-CSF receptor expression but not terminal granulopoiesis via site-selective inhibition of C/EBP DNA binding

7 July 2018

1 reference

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CEBPA mutations in younger adults with acute myeloid leukemia and normal cytogenetics: prognostic relevance and analysis of cooperating mutations

7 July 2018

1 reference

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C/EBPalpha and G-CSF receptor signals cooperate to induce the myeloperoxidase and neutrophil elastase genes

7 July 2018

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CCAAT/enhancer binding protein alpha is a regulatory switch sufficient for induction of granulocytic development from bipotential myeloid progenitors

7 July 2018

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Bone marrow adherent layers inhibit apoptosis of acute myeloid leukemia cells.

7 July 2018

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Integration of cytogenetic and molecular alterations in risk stratification of 318 patients with de novo non-M3 acute myeloid leukemia.

7 July 2018

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CXCR4-SERINE339 regulates cellular adhesion, retention and mobilization, and is a marker for poor prognosis in acute myeloid leukemia.

26 October 2018

1 reference

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The prognostic value of CXCR4 in acute myeloid leukemia

26 October 2018

1 reference

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DNMT3A mutations in acute myeloid leukemia: stability during disease evolution and clinical implications

26 October 2018

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WT1 mutation in 470 adult patients with acute myeloid leukemia: stability during disease evolution and implication of its incorporation into a survival scoring system.

26 October 2018

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Distinct clinical and biologic characteristics in adult acute myeloid leukemia bearing the isocitrate dehydrogenase 1 mutation.

26 October 2018

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AML1/RUNX1 mutations in 470 adult patients with de novo acute myeloid leukemia: prognostic implication and interaction with other gene alterations.

26 October 2018

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DOG 1.0: illustrator of protein domain structures

26 October 2018

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Characterization of acute myeloid leukemia with PTPN11 mutation: the mutation is closely associated with NPM1 mutation but inversely related to FLT3/ITD.

26 October 2018

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CXCR4 is a prognostic marker in acute myelogenous leukemia.

26 October 2018

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Characterization of CEBPA mutations in acute myeloid leukemia: most patients with CEBPA mutations have biallelic mutations and show a distinct immunophenotype of the leukemic cells.

26 October 2018

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CXCR4 chemokine receptors (CD184) and alpha4beta1 integrins mediate spontaneous migration of human CD34 progenitors and acute myeloid leukaemia cells beneath marrow stromal cells (pseudoemperipolesis).

26 October 2018

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Clinical and biological implications of partial tandem duplication of the MLL gene in acute myeloid leukemia without chromosomal abnormalities at 11q23.

26 October 2018

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The transcription factor HNF1 acts with C/EBP alpha to synergistically activate the human albumin promoter through a novel domain

26 October 2018

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12 December 2020

Nucleophosmin mutations in de novo acute myeloid leukemia: the age-dependent incidences and the stability during disease evolution

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12 December 2020

Acquisition of JAK2, PTPN11, and RAS mutations during disease progression in primary myelodysplastic syndrome

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12 December 2020

RUNX1 gene mutation in primary myelodysplastic syndrome--the mutation can be detected early at diagnosis or acquired during disease progression and is associated with poor outcome

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12 December 2020

Expression of angiopoietins and vascular endothelial growth factors and their clinical significance in acute myeloid leukemia

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12 December 2020

Favorable prognostic significance of CEBPA mutations in patients with de novo acute myeloid leukemia: a study from the Acute Leukemia French Association (ALFA)

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12 December 2020

Distinct clinical and biological features of de novo acute myeloid leukemia with additional sex comb-like 1 (ASXL1) mutations

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12 December 2020

The prognostic impact and stability of Isocitrate dehydrogenase 2 mutation in adult patients with acute myeloid leukemia

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12 December 2020

10.3324/HAEMATOL.2014.107821

Identifiers

DOI

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16 February 2020

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16 February 2020

PubMed publication ID

25193961

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25193961 AND SRC:MED&resulttype=core&format=json