Metastasis and bone loss: advancing treatment and prevention. (Q34617837)

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2 February 2020

review article

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title

Metastasis and bone loss: advancing treatment and prevention (English)

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7

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Peter I Croucher

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Ingunn Holen

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Larry J Suva

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author name string

Robert E Coleman

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2 February 2020

Allan Lipton

2

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G David Roodman

3

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Brendon F Boyce

5

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2 February 2020

Adam M Brufsky

6

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2 February 2020

Julie R Gralow

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2 February 2020

Peyman Hadji

10

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Gregory R Mundy

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Matthew R Smith

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Theresa A Guise

4

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publication date

15 May 2010

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2 February 2020

published in

Cancer Treatment Reviews

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volume

36

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issue

8

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page(s)

615-620

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Anti-tumour effects of bisphosphonates--what have we learned from in vivo models?

2 February 2020

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1 reference

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7 July 2018

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7 July 2018

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Inhibiting Dickkopf-1 (Dkk1) removes suppression of bone formation and prevents the development of osteolytic bone disease in multiple myeloma.

7 July 2018

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7 July 2018

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Integrated analysis of zoledronic acid for prevention of aromatase inhibitor-associated bone loss in postmenopausal women with early breast cancer receiving adjuvant letrozole

7 July 2018

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Practical guidance for the management of aromatase inhibitor-associated bone loss

7 July 2018

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Increasing Wnt signaling in the bone marrow microenvironment inhibits the development of myeloma bone disease and reduces tumor burden in bone in vivo

7 July 2018

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Toremifene increases bone mineral density in men receiving androgen deprivation therapy for prostate cancer: interim analysis of a multicenter phase 3 clinical study

7 July 2018

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A cathepsin K inhibitor reduces breast cancer induced osteolysis and skeletal tumor burden.

7 July 2018

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Tumor alphavbeta3 integrin is a therapeutic target for breast cancer bone metastases.

7 July 2018

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The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development.

7 July 2018

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Meta-analysis of clodronate and breast cancer survival

7 July 2018

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Antitumor effects of clinical dosing regimens of bisphosphonates in experimental breast cancer bone metastasis

7 July 2018

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Ki26894, a novel transforming growth factor-beta type I receptor kinase inhibitor, inhibits in vitro invasion and in vivo bone metastasis of a human breast cancer cell line.

7 July 2018

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Role of CCR1 and CCR5 in homing and growth of multiple myeloma and in the development of osteolytic lesions: a study in the 5TMM model

7 July 2018

1 reference

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Antibody-based inhibition of DKK1 suppresses tumor-induced bone resorption and multiple myeloma growth in vivo

7 July 2018

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SRC inhibitors in metastatic bone disease

7 July 2018

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Matrix elasticity directs stem cell lineage specification

7 July 2018

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The hedgehog signaling molecule Gli2 induces parathyroid hormone-related peptide expression and osteolysis in metastatic human breast cancer cells

7 July 2018

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Inhibition of protein kinase c-Src reduces the incidence of breast cancer metastases and increases survival in mice: implications for therapy

7 July 2018

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Reduction in bone relapse and improved survival with oral clodronate for adjuvant treatment of operable breast cancer [ISRCTN83688026]

7 July 2018

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Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer.

7 July 2018

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Mechanisms of bone metastasis

7 July 2018

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The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma

7 July 2018

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A causal role for endothelin-1 in the pathogenesis of osteoblastic bone metastases

7 July 2018

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7 July 2018

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Antisense inhibition of macrophage inflammatory protein 1-alpha blocks bone destruction in a model of myeloma bone disease

7 July 2018

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TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development

7 July 2018

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Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis

7 July 2018

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An experimental model of bone metastasis by human lung cancer cells: the role of parathyroid hormone-related protein in bone metastasis.

7 July 2018

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Randomized, double-blind study of denosumab versus zoledronic acid in the treatment of bone metastases in patients with advanced cancer (excluding breast and prostate cancer) or multiple myeloma.

7 July 2018

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Zoledronic acid effectively prevents aromatase inhibitor-associated bone loss in postmenopausal women with early breast cancer receiving adjuvant letrozole: Z-FAST study 36-month follow-up results.

26 October 2018

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Effect of denosumab on bone mineral density in women receiving adjuvant aromatase inhibitors for non-metastatic breast cancer: subgroup analyses of a phase 3 study

26 October 2018

1 reference

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Zerumbone abolishes RANKL-induced NF-kappaB activation, inhibits osteoclastogenesis, and suppresses human breast cancer-induced bone loss in athymic nude mice

26 October 2018

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Prevention of anastrozole-induced bone loss with monthly oral ibandronate during adjuvant aromatase inhibitor therapy for breast cancer.

26 October 2018

1 reference

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Randomized controlled trial of zoledronic acid to prevent bone loss in men receiving androgen deprivation therapy for nonmetastatic prostate cancer

26 October 2018

1 reference

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Pamidronate to prevent bone loss during androgen-deprivation therapy for prostate cancer

26 October 2018

1 reference

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Therapeutic efficacy of a soluble receptor activator of nuclear factor kappaB-IgG Fc fusion protein in suppressing bone resorption and hypercalcemia in a model of humoral hypercalcemia of malignancy.

26 October 2018

1 reference

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Adjuvant clodronate treatment does not reduce the frequency of skeletal metastases in node-positive breast cancer patients: 5-year results of a randomized controlled trial

26 October 2018

1 reference

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Recombinant osteoprotegerin decreases tumor burden and increases survival in a murine model of multiple myeloma

26 October 2018

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12 December 2020

Zoledronic Acid Prevents Cancer Treatment–Induced Bone Loss in Premenopausal Women Receiving Adjuvant Endocrine Therapy for Hormone-Responsive Breast Cancer: A Report From the Austrian Breast and Colorectal Cancer Study Group

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12 December 2020

Reduction in new metastases in breast cancer with adjuvant clodronate treatment

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12 December 2020

Macrophage inflammatory protein 1-alpha is a potential osteoclast stimulatory factor in multiple myeloma

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12 December 2020

Bisphosphonates in cancer therapy

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12 December 2020

Risk of fracture after androgen deprivation for prostate cancer

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12 December 2020

Effect of once-weekly oral alendronate on bone loss in men receiving androgen deprivation therapy for prostate cancer: a randomized trial

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12 December 2020

10.1016/J.CTRV.2010.04.003

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20478658 AND SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20478658 AND SRC:MED&resulttype=core&format=json

2 February 2020

PubMed publication ID

20478658

1 reference