Transmodulation of cell surface regulatory molecules via ectodomain shedding (Q34584816)

3 August 2017

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title

Transmodulation of cell surface regulatory molecules via ectodomain shedding (English)

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3 August 2017

Persio Dello Sbarba

1

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3 August 2017

Elisabetta Rovida

series ordinal

2

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3 August 2017

publication date

1 January 2002

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3 August 2017

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3 August 2017

volume

383

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3 August 2017

issue

1

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3 August 2017

page(s)

69-83

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Cellular Redistribution of Protein Tyrosine Phosphatases LAR and PTPσ by Inducible Proteolytic Processing

3 August 2017

cites work

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Shedding of interleukin-6 receptor and tumor necrosis factor alpha. Contribution of the stalk sequence to the cleavage pattern of transmembrane proteins

21 January 2018

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Shedding of growth hormone-binding protein is inhibited by hydroxamic acid-based protease inhibitors: proposed mechanism of activation of growth hormone-binding protein secretase

21 January 2018

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Diverse cell surface protein ectodomains are shed by a system sensitive to metalloprotease inhibitors.

21 January 2018

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Transforming growth factor-alpha and beta-amyloid precursor protein share a secretory mechanism.

21 January 2018

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CD43, the major sialoglycoprotein of human leukocytes, is proteolytically cleaved from the surface of stimulated lymphocytes and granulocytes

21 January 2018

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Regulation of the activity of matriptase on epithelial cell surfaces by a blood-derived factor

21 January 2018

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A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells

21 January 2018

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Increased level of serum HLA class I antigens in patients with systemic lupus in patients with systemic lupus erythematosus. Correlation with disease activity

21 January 2018

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Calcium regulates processing of the Alzheimer amyloid protein precursor in a protein kinase C-independent manner

21 January 2018

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TrkA receptor ectodomain cleavage generates a tyrosine-phosphorylated cell-associated fragment

21 January 2018

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T lymphocytes conditioned with Interferon beta induce membrane and soluble VCAM on human brain endothelial cells

21 January 2018

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Cleavage of the epidermal growth factor receptor by a membrane-bound leupeptin-sensitive protease active in nonionic detergent lysates of senescent but not young human diploid fibroblasts.

21 January 2018

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125I-labeled human epidermal growth factor. Binding, internalization, and degradation in human fibroblasts

21 January 2018

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Src tyrosine kinases, Galpha subunits, and H-Ras share a common membrane-anchored scaffolding protein, caveolin. Caveolin binding negatively regulates the auto-activation of Src tyrosine kinases

21 January 2018

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A metalloprotease inhibitor blocks shedding of the 80-kD TNF receptor and TNF processing in T lymphocytes

21 January 2018

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Soluble complement receptor type 1 (CD35) is released from leukocytes by surface cleavage

21 January 2018

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Apical Enrichment of Human EGF Precursor in Madin-Darby Canine Kidney Cells Involves Preferential Basolateral Ectodomain Cleavage Sensitive to a Metalloprotease Inhibitor

21 January 2018

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Serotonin 5-HT2a and 5-HT2c receptors stimulate amyloid precursor protein ectodomain secretion

21 January 2018

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Stimulation of cleavage of membrane proteins by calmodulin inhibitors

21 January 2018

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Stimulation-induced down-regulation of tumor necrosis factor-alpha converting enzyme

21 January 2018

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Shedding of CD163, a novel regulatory mechanism for a member of the scavenger receptor cysteine-rich family

21 January 2018

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Proteolytic release of membrane-bound angiotensin-converting enzyme: role of the juxtamembrane stalk sequence

21 January 2018

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Increased shedding of angiotensin-converting enzyme by a mutation identified in the stalk region

21 January 2018

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Ectodomain shedding of TGF-alpha and other transmembrane proteins is induced by receptor tyrosine kinase activation and MAP kinase signaling cascades

21 January 2018

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Shedding of syndecan-1 and -4 ectodomains is regulated by multiple signaling pathways and mediated by a TIMP-3-sensitive metalloproteinase

21 January 2018

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Pneumocystis carinii enhances soluble mannose receptor production by macrophages

21 January 2018

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Function of an axonal chemoattractant modulated by metalloprotease activity

21 January 2018

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Suramin modulates cellular levels of hepatocyte growth factor receptor by inducing shedding of a soluble form.

21 January 2018

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The shedding of membrane-anchored heparin-binding epidermal-like growth factor is regulated by the Raf/mitogen-activated protein kinase cascade and by cell adhesion and spreading

21 January 2018

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Phorbol ester- and growth factor-induced growth hormone (GH) receptor proteolysis and GH-binding protein shedding: relationship to GH receptor down-regulation

21 January 2018

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Structural characterization of the circulating soluble FGF receptors reveals multiple isoforms generated by secretion and ectodomain shedding

21 January 2018

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PECAM-1 shedding during apoptosis generates a membrane-anchored truncated molecule with unique signaling characteristics

21 January 2018

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A metalloprotease-disintegrin, MDC9/meltrin-gamma/ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.

21 January 2018

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Human dendritic cells shed a functional, soluble form of the mannose receptor

21 January 2018

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Soluble human interleukin-4 receptor is produced by activated T cells under the control of metalloproteinases

21 January 2018

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Membrane-type 1 matrix metalloproteinase cleaves CD44 and promotes cell migration

21 January 2018

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Proteolysis of the urokinase-type plasminogen activator receptor by metalloproteinase-12: implication for angiogenesis in fibrin matrices

21 January 2018

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Use of a mutant cell line to study the kinetics and function of O-linked glycosylation of low density lipoprotein receptors

21 January 2018

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Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease

21 January 2018

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Release of soluble ICAM-1 from human lung fibroblasts, aortic smooth muscle cells, dermal microvascular endothelial cells, bronchial epithelial cells, and keratinocytes

21 January 2018

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The CD27 membrane receptor, a lymphocyte-specific member of the nerve growth factor receptor family, gives rise to a soluble form by protein processing that does not involve receptor endocytosis

21 January 2018

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Two different biosynthetic pathways for the secretion of Qa region-associated class I antigens by mouse lymphocytes

21 January 2018

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Membrane-anchored growth factors.

21 January 2018

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Different proteolytic mechanisms involved in Fc gamma RIIIb shedding from human neutrophils

21 January 2018

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Cleavage and shedding of the TSH receptor

21 January 2018

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Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha

21 January 2018

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Receptor-mediated transcellular transport of immunoglobulin: synthesis of secretory component as multiple and larger transmembrane forms

21 January 2018

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The soluble interleukin-6 receptor is generated by shedding

21 January 2018

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Further evidence for a common mechanism for shedding of cell surface proteins

21 January 2018

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Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion

21 January 2018

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Albumin inhibits neutrophil spreading and hydrogen peroxide release by blocking the shedding of CD43 (sialophorin, leukosialin).

21 January 2018

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The transforming receptor tyrosine kinase, Axl, is post-translationally regulated by proteolytic cleavage

21 January 2018

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Furin-dependent intracellular activation of the human stromelysin-3 zymogen

21 January 2018

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Cleavage of membrane-bound CD40 ligand is not required for inducing B cell proliferation and differentiation

21 January 2018

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Tumor necrosis factor-alpha-converting enzyme is required for cleavage of erbB4/HER4

21 January 2018

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Metalloprotease-disintegrin MDC9: intracellular maturation and catalytic activity

21 January 2018

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The distal ectodomain of angiotensin-converting enzyme regulates its cleavage-secretion from the cell surface

21 January 2018

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Phorbol ester-induced juxtamembrane cleavage of angiotensin-converting enzyme is not inhibited by a stalk containing intrachain disulfides.

21 January 2018

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Modulation of juxtamembrane cleavage ("shedding") of angiotensin-converting enzyme by stalk glycosylation: evidence for an alternative shedding protease.

21 January 2018

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Tyrosine phosphorylation-dependent and -independent associations of protein kinase C-delta with Src family kinases in the RBL-2H3 mast cell line: regulation of Src family kinase activity by protein kinase C-delta

21 January 2018

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Regulated shedding of syndecan-1 and -4 ectodomains by thrombin and growth factor receptor activation.

21 January 2018

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Matrix Metalloproteinase-3 Releases Active Heparin-binding EGF-like Growth Factor by Cleavage at a Specific Juxtamembrane Site

21 January 2018

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Consequences of exclusive expression in vivo of Kit-ligand lacking the major proteolytic cleavage site

21 January 2018

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Downregulation of Fas ligand by shedding

21 January 2018

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A dual signaling cascade that regulates the ectodomain shedding of heparin-binding epidermal growth factor-like growth factor

21 January 2018

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Selective cleavage of the heregulin receptor ErbB-4 by protein kinase C activation

21 January 2018

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Constitutive proteolysis of the ErbB-4 receptor tyrosine kinase by a unique, sequential mechanism.

21 January 2018

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Tyrosine phosphorylation and proteolysis. Pervanadate-induced, metalloprotease-dependent cleavage of the ErbB-4 receptor and amphiregulin.

21 January 2018

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A role for the immunoglobulin-like domain of the human IL-6 receptor. Intracellular protein transport and shedding

21 January 2018

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A cellular striptease act.

21 January 2018

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MDC9, a widely expressed cellular disintegrin containing cytoplasmic SH3 ligand domains

21 January 2018

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Tumor necrosis factor-alpha converting enzyme (TACE) is a growth hormone binding protein (GHBP) sheddase: the metalloprotease TACE/ADAM-17 is critical for (PMA-induced) GH receptor proteolysis and GHBP generation

21 January 2018

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Heregulin-dependent Trafficking and Cleavage of ErbB-4

21 January 2018

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Role of the Juxtamembrane Domains of the Transforming Growth Factor-α Precursor and the β-Amyloid Precursor Protein in Regulated Ectodomain Shedding

21 January 2018

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21 January 2018

Identifiers

DOI

10.1515/BC.2002.007

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3 August 2017

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