Attenuation of human respiratory syncytial virus by genome-scale codon-pair deoptimization (Q34583420)

3 August 2017

title

Attenuation of human respiratory syncytial virus by genome-scale codon-pair deoptimization (English)

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respiratory syncytial virus

3 August 2017

main subject

object named as

human respiratory syncytial virus

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1

Cyril Le Nouën

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Eckard Wimmer

7

object named as

Eckard Wimmer

1 reference

3 August 2017

Masfique Mehedi

6

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author name string

Cyril Le Nouën

1

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3 August 2017

Linda G Brock

2

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3 August 2017

Cindy Luongo

3

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3 August 2017

Thomas McCarty

4

1 reference

3 August 2017

Lijuan Yang

5

1 reference

3 August 2017

Steffen Mueller

8

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3 August 2017

Peter L Collins

9

1 reference

3 August 2017

Ursula J Buchholz

10

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3 August 2017

Joshua M DiNapoli

11

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3 August 2017

language of work or name

English

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publication date

25 August 2014

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Proceedings of the National Academy of Sciences of the United States of America

3 August 2017

published in

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3 August 2017

volume

111

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3 August 2017

issue

36

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3 August 2017

page(s)

13169-13174

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Changes in codon-pair bias of human immunodeficiency virus type 1 have profound effects on virus replication in cell culture

3 August 2017

cites work

1 reference

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Deliberate reduction of hemagglutinin and neuraminidase expression of influenza virus leads to an ultraprotective live vaccine in mice

7 July 2018

1 reference

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Respiratory syncytial virus modified by deletions of the NS2 gene and amino acid S1313 of the L polymerase protein is a temperature-sensitive, live-attenuated vaccine candidate that is phenotypically stable at physiological temperature

7 July 2018

1 reference

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Increased genetic and phenotypic stability of a promising live-attenuated respiratory syncytial virus vaccine candidate by reverse genetics

7 July 2018

1 reference

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Bats host major mammalian paramyxoviruses

7 July 2018

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Progress in understanding and controlling respiratory syncytial virus: still crazy after all these years

7 July 2018

1 reference

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Designed reduction of Streptococcus pneumoniae pathogenicity via synthetic changes in virulence factor codon-pair bias

7 July 2018

1 reference

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Live attenuated influenza virus vaccines by computer-aided rational design

7 July 2018

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The burden of respiratory syncytial virus infection in young children

7 July 2018

1 reference

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Virus attenuation by genome-scale changes in codon pair bias

7 July 2018

1 reference

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Viral and host factors in human respiratory syncytial virus pathogenesis

7 July 2018

1 reference

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Large scale comparative codon-pair context analysis unveils general rules that fine-tune evolution of mRNA primary structure.

7 July 2018

1 reference

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tRNA properties help shape codon pair preferences in open reading frames

7 July 2018

1 reference

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Granulocyte-macrophage colony-stimulating factor expressed by recombinant respiratory syncytial virus attenuates viral replication and increases the level of pulmonary antigen-presenting cells

7 July 2018

1 reference

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Generation of bovine respiratory syncytial virus (BRSV) from cDNA: BRSV NS2 is not essential for virus replication in tissue culture, and the human RSV leader region acts as a functional BRSV genome promoter

7 July 2018

1 reference

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A single nucleotide substitution in the transcription start signal of the M2 gene of respiratory syncytial virus vaccine candidate cpts248/404 is the major determinant of the temperature-sensitive and attenuation phenotypes

7 July 2018

1 reference

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Production of infectious human respiratory syncytial virus from cloned cDNA confirms an essential role for the transcription elongation factor from the 5' proximal open reading frame of the M2 mRNA in gene expression and provides a capability for va

7 July 2018

1 reference

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Nonrandom utilization of codon pairs in Escherichia coli

7 July 2018

1 reference

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Codon contexts from weakly expressed genes reduce expression in vivo

7 July 2018

1 reference

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Coupled translation of the respiratory syncytial virus M2 open reading frames requires upstream sequences.

7 July 2018

1 reference

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Increased expression of the N protein of respiratory syncytial virus stimulates minigenome replication but does not alter the balance between the synthesis of mRNA and antigenome

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.1411290111

Identification of a recombinant live attenuated respiratory syncytial virus vaccine candidate that is highly attenuated in infants

21 January 2018

1 reference

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Enhanced pulmonary histopathology is observed in cotton rats immunized with formalin-inactivated respiratory syncytial virus (RSV) or purified F glycoprotein and challenged with RSV 3-6 months after immunization

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.1411290111

21 January 2018

Identifiers

DOI

10.1073/PNAS.1411290111

1 reference

3 August 2017

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3 August 2017

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