The MuSK activator agrin has a separate role essential for postnatal maintenance of neuromuscular synapses (Q34581104)

25368159

3 August 2017

title

The MuSK activator agrin has a separate role essential for postnatal maintenance of neuromuscular synapses (English)

1 reference

3 August 2017

4

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7 June 2020

Robert W Burgess

5

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7 June 2020

author name string

Tohru Tezuka

1

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7 June 2020

Akane Inoue

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7 June 2020

Taisuke Hoshi

3

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Ryo Ueta

6

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Yuji Yamanashi

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language of work or name

English

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publication date

3 November 2014

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25368159

Proceedings of the National Academy of Sciences of the United States of America

3 August 2017

published in

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volume

111

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issue

46

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page(s)

16556-16561

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describes a project that uses

7 June 2020

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4246289/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Agrin and synaptic laminin are required to maintain adult neuromuscular junctions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246289

Lrp4 is a retrograde signal for presynaptic differentiation at neuromuscular synapses

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246289

Distinct roles of muscle and motoneuron LRP4 in neuromuscular junction formation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246289

Congenital myasthenic syndromes: achievements and limitations of phenotype-guided gene-after-gene sequencing in diagnostic practice: a study of 680 patients

7 July 2018

1 reference

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LG2 agrin mutation causing severe congenital myasthenic syndrome mimics functional characteristics of non-neural (z-) agrin.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246289

A valid mouse model of AGRIN-associated congenital myasthenic syndrome.

7 July 2018

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Role of extracellular matrix proteins and their receptors in the development of the vertebrate neuromuscular junction

7 July 2018

1 reference

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The cytoplasmic adaptor protein Dok7 activates the receptor tyrosine kinase MuSK via dimerization

7 July 2018

1 reference

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To build a synapse: signaling pathways in neuromuscular junction assembly

7 July 2018

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Identification of an agrin mutation that causes congenital myasthenia and affects synapse function.

7 July 2018

1 reference

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Dok-7 activates the muscle receptor kinase MuSK and shapes synapse formation

7 July 2018

1 reference

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Dok-7/MuSK signaling and a congenital myasthenic syndrome.

7 July 2018

1 reference

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LRP4 serves as a coreceptor of agrin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246289

Lrp4 is a receptor for Agrin and forms a complex with MuSK

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246289

Muscle-wide secretion of a miniaturized form of neural agrin rescues focal neuromuscular innervation in agrin mutant mice

7 July 2018

1 reference

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Mutations causing DOK7 congenital myasthenia ablate functional motifs in Dok-7.

7 July 2018

1 reference

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MuSK controls where motor axons grow and form synapses

7 July 2018

1 reference

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Distinct target-derived signals organize formation, maturation, and maintenance of motor nerve terminals

7 July 2018

1 reference

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7 July 2018

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Dok-7 mutations underlie a neuromuscular junction synaptopathy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246289

The muscle protein Dok-7 is essential for neuromuscular synaptogenesis

7 July 2018

1 reference

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Synapse disassembly and formation of new synapses in postnatal muscle upon conditional inactivation of MuSK.

7 July 2018

1 reference

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Agrin promotes synaptic differentiation by counteracting an inhibitory effect of neurotransmitter

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246289

Neurotransmitter acetylcholine negatively regulates neuromuscular synapse formation by a Cdk5-dependent mechanism

7 July 2018

1 reference

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Antibodies in myasthenia gravis and related disorders

7 July 2018

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Sleuthing molecular targets for neurological diseases at the neuromuscular junction

7 July 2018

1 reference

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Aberrant patterning of neuromuscular synapses in choline acetyltransferase-deficient mice

7 July 2018

1 reference

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Roles of neurotransmitter in synapse formation: development of neuromuscular junctions lacking choline acetyltransferase

7 July 2018

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Building the vertebrate neuromuscular synapse

7 July 2018

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Induction, assembly, maturation and maintenance of a postsynaptic apparatus

7 July 2018

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Distinct roles of nerve and muscle in postsynaptic differentiation of the neuromuscular synapse

7 July 2018

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Alternatively spliced isoforms of nerve- and muscle-derived agrin: their roles at the neuromuscular junction

7 July 2018

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Association of muscle-specific kinase MuSK with the acetylcholine receptor in mammalian muscle.

7 July 2018

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Defective neuromuscular synaptogenesis in agrin-deficient mutant mice

7 July 2018

1 reference

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The receptor tyrosine kinase MuSK is required for neuromuscular junction formation in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246289

Aberrant differentiation of neuromuscular junctions in mice lacking s-laminin/laminin beta 2

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246289

MUSK, a new target for mutations causing congenital myasthenic syndrome

7 July 2018

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Crossref

https://api.crossref.org/works/10.1073/PNAS.1408409111

Restoration of synapse formation in Musk mutant mice expressing a Musk/Trk chimeric receptor.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073/PNAS.1408409111

A synaptic laminin–calcium channel interaction organizes active zones in motor nerve terminals

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073/PNAS.1408409111

21 January 2018

Identifiers

DOI

10.1073/PNAS.1408409111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25368159 AND SRC:MED&resulttype=core&format=json

7 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25368159 AND SRC:MED&resulttype=core&format=json

7 June 2020

25368159

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