Infection of human cancer cells with myxoma virus requires Akt activation via interaction with a viral ankyrin-repeat host range factor. (Q34574890)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16537421 AND SRC:MED&resulttype=core&format=json

17 January 2020

title

Infection of human cancer cells with myxoma virus requires Akt activation via interaction with a viral ankyrin-repeat host range factor (English)

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17 January 2020

myxoma virus

1 reference

3

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17 January 2020

9

Grant McFadden

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17 January 2020

author name string

Gen Wang

1

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17 January 2020

John W Barrett

2

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17 January 2020

Steven J Werden

4

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17 January 2020

James B Johnston

5

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17 January 2020

Xiujuan Gao

6

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17 January 2020

Mei Sun

7

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17 January 2020

Jin Q Cheng

8

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17 January 2020

language of work or name

English

0 references

publication date

14 March 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16537421 AND SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

17 January 2020

number of pages

6

1 reference

based on heuristic

inferred from page(s)

published in

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17 January 2020

volume

103

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17 January 2020

issue

12

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17 January 2020

page(s)

4640-4645

1 reference

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Myxoma virus M11L blocks apoptosis through inhibition of conformational activation of Bax at the mitochondria

17 January 2020

cites work

1 reference

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Myxoma virus is a novel oncolytic virus with significant antitumor activity against experimental human gliomas

7 July 2018

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Myxoma virus M-T5 protects infected cells from the stress of cell cycle arrest through its interaction with host cell cullin-1

7 July 2018

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Activation of the N-Ras-PI3K-Akt-mTOR pathway by hepatitis C virus: control of cell survival and viral replication

7 July 2018

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Flavivirus Activates Phosphatidylinositol 3-Kinase Signaling To Block Caspase-Dependent Apoptotic Cell Death at the Early Stage of Virus Infection

7 July 2018

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PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth

7 July 2018

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The activation of Akt/PKB signaling pathway and cell survival.

7 July 2018

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7 July 2018

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

7 July 2018

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Insulin-like growth factor ligands, receptors, and binding proteins in cancer.

7 July 2018

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The ankyrin repeat as molecular architecture for protein recognition

7 July 2018

1 reference

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Advances in protein kinase B signalling: AKTion on multiple fronts

7 July 2018

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The pivotal role of phosphatidylinositol 3-kinase-Akt signal transduction in virus survival

7 July 2018

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Role of the serine-threonine kinase PAK-1 in myxoma virus replication

7 July 2018

1 reference

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To kill or be killed: viral evasion of apoptosis

7 July 2018

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HCV NS5A interacts with p53 and inhibits p53-mediated apoptosis

7 July 2018

1 reference

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Immune responses to myxoma virus

7 July 2018

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The protein kinase B/Akt signalling pathway in human malignancy

7 July 2018

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PKB/Akt: a key mediator of cell proliferation, survival and insulin responses?

7 July 2018

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AKT plays a central role in tumorigenesis

7 July 2018

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Human cytomegalovirus up-regulates the phosphatidylinositol 3-kinase (PI3-K) pathway: inhibition of PI3-K activity inhibits viral replication and virus-induced signaling

7 July 2018

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The phosphoinositide 3-OH kinase/AKT2 pathway as a critical target for farnesyltransferase inhibitor-induced apoptosis

7 July 2018

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Cellular survival: a play in three Akts

7 July 2018

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The Complete DNA Sequence of Myxoma Virus

7 July 2018

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7 July 2018

Viruses and Apoptosis

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Role of phosphoinositide 3-kinase in activation of ras and mitogen-activated protein kinase by epidermal growth factor

7 July 2018

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Inhibitory specificity of the anti-inflammatory myxoma virus serpin, SERP-1

7 July 2018

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Phosphatidylinositol 3-Kinase Is Required for Integrin-Stimulated AKT and Raf-1/Mitogen-Activated Protein Kinase Pathway Activation

7 July 2018

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The purified myxoma virus gamma interferon receptor homolog M-T7 interacts with the heparin-binding domains of chemokines

7 July 2018

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Disruption of M-T5, a novel myxoma virus gene member of poxvirus host range superfamily, results in dramatic attenuation of myxomatosis in infected European rabbits

7 July 2018

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The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

7 July 2018

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Deletion analysis of two tandemly arranged virulence genes in myxoma virus, M11L and myxoma growth factor

7 July 2018

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7 July 2018

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A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells

21 January 2018

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Respiratory syncytial virus inhibits apoptosis and induces NF-kappa B activity through a phosphatidylinositol 3-kinase-dependent pathway

21 January 2018

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RETRACTED: Activation of phosphatidylinositol 3-kinase/Akt pathway by androgen through interaction of p85alpha, androgen receptor, and Src.

21 January 2018

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Frequent activation of AKT2 and induction of apoptosis by inhibition of phosphoinositide-3-OH kinase/Akt pathway in human ovarian cancer

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16537421

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0509341103

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16537421 AND SRC:MED&resulttype=core&format=json

17 January 2020

0 references

1 reference

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17 January 2020

PubMed publication ID

16537421

1 reference