Apoptosis: implications of basic research for clinical oncology (Q34571783)

3 August 2017

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title

Apoptosis: implications of basic research for clinical oncology (English)

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3 August 2017

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I Tamm

1

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3 August 2017

F Schriever

series ordinal

2

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3 August 2017

B Dörken

series ordinal

3

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3 August 2017

publication date

1 January 2001

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Lancet Oncology Commission

3 August 2017

published in

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3 August 2017

volume

2

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3 August 2017

issue

1

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3 August 2017

page(s)

33-42

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Mechanisms of apoptosis avoidance in cancer.

3 August 2017

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7 January 2021

Mitochondrial control of cell death

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7 January 2021

Rb function in cell-cycle regulation and apoptosis

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7 January 2021

Action of Myc in vivo - proliferation and apoptosis

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7 January 2021

The Bcl-2 protein family: arbiters of cell survival

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7 January 2021

Mitochondria and apoptosis

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Apoptotic protease activating factor 1 (Apaf-1)-independent cell death suppression by Bcl-2.

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Regulation of apoptosis by bcl-2 family proteins and its role in cancer and chemoresistance.

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Elucidating cell signaling mechanisms using antisense technology

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All along the watchtower: on the regulation of apoptosis regulators.

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Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

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7 January 2021

Bax directly induces release of cytochrome c from isolated mitochondria

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7 January 2021

The caspase family of cysteine proteases

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7 January 2021

Noncaspase proteases in apoptosis

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7 January 2021

IAP family proteins--suppressors of apoptosis

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A Single BIR Domain of XIAP Sufficient for Inhibiting Caspases

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Suppression of TNF-alpha-induced apoptosis by NF-kappaB

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7 January 2021

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

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7 January 2021

The inhibitors of apoptosis (IAPs) and their emerging role in cancer

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7 January 2021

Control of apoptosis and mitotic spindle checkpoint by survivin

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7 January 2021

Survivin initiates cell cycle entry by the competitive interaction with Cdk4/p16(INK4a) and Cdk2/cyclin E complex activation.

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7 January 2021

Survivin' cell-separation anxiety

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7 January 2021

Pleiotropic cell-division defects and apoptosis induced by interference with survivin function

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7 January 2021

Inhibition of death receptor signals by cellular FLIP

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7 January 2021

The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways

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7 January 2021

Death receptors: signaling and modulation

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7 January 2021

The modular nature of apoptotic signaling proteins

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7 January 2021

The CD95/CD95 ligand system is not the major effector in anticancer drug-mediated apoptosis

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7 January 2021

Involvement of the CD95 (APO–1/Fas) receptor/ligand system in drug–induced apoptosis in leukemia cells

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7 January 2021

Caspase-8/FLICE functions as an executioner caspase in anticancer drug-induced apoptosis

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7 January 2021

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7 January 2021

Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family

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7 January 2021

Identification and characterization of a new member of the TNF family that induces apoptosis

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7 January 2021

Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

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7 January 2021

Safety and antitumor activity of recombinant soluble Apo2 ligand

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7 January 2021

Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand

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7 January 2021

Steering anti-cancer drugs away from the TRAIL

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7 January 2021

Escaping cell death: survival proteins in cancer

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7 January 2021

Overexpression of resistance-related proteins (metallothioneins, glutathione-S-transferase pi, heat shock protein 27, and lung resistance-related protein) in osteosarcoma. Relationship with poor prognosis

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7 January 2021

Involvement of the bcl-2 gene in human follicular lymphoma

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7 January 2021

Phase I clinical and pharmacokinetic study of bcl-2 antisense oligonucleotide therapy in patients with non-Hodgkin's lymphoma

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7 January 2021

A recombinant defective adenoviral agent expressing anti-bcl-2 ribozyme promotes apoptosis of bcl-2-expressing human prostate cancer cells

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7 January 2021

ICE-protease inhibitors block murine liver injury and apoptosis caused by CD95 or by TNF-alpha

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7 January 2021

TRAIL: a molecule with multiple receptors and control mechanisms

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7 January 2021

Inhibitor of apoptosis proteins physically interact with and block apoptosis induced by Drosophila proteins HID and GRIM.

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7 January 2021

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

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7 January 2021

Structural and biochemical basis of apoptotic activation by Smac/DIABLO

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7 January 2021

Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer

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7 January 2021

10.1016/S1470-2045(00)00193-5

Identifiers

DOI

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3 August 2017

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