Spreading of silent chromatin: inaction at a distance (Q34567039)

3 August 2017

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title

Spreading of silent chromatin: inaction at a distance (English)

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3 August 2017

1

Paul B Talbert

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3 August 2017

2

Steven Henikoff

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3 August 2017

publication date

1 October 2006

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3 August 2017

published in

Nature Reviews Genetics

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3 August 2017

volume

7

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3 August 2017

issue

10

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3 August 2017

page(s)

793-803

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Types of visible variations induced by X-rays inDrosophila

3 August 2017

cites work

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Variegation in Drosophila and the Inert Chromosome Regions

31 March 2020

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Gene regulation by proteins acting nearby and at a distance

31 March 2020

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Silencing of mouse Aprt is a gradual process in differentiated cells

31 March 2020

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SINE retroposons can be used in vivo as nucleation centers for de novo methylation

31 March 2020

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Delving into the diversity of facultative heterochromatin: the epigenetics of the inactive X chromosome

31 March 2020

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Dosage compensation in flies: mechanism, models, mystery.

31 March 2020

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Transcriptional silencing in Saccharomyces cerevisiae and Schizosaccharomyces pombe

31 March 2020

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Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription

31 March 2020

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Silenced chromatin is permissive to activator binding and PIC recruitment

31 March 2020

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Mechanism of transcriptional silencing in yeast

31 March 2020

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Silent domains are assembled continuously from the telomere and are defined by promoter distance and strength, and by SIR3 dosage

31 March 2020

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Steps in assembly of silent chromatin in yeast: Sir3-independent binding of a Sir2/Sir4 complex to silencers and role for Sir2-dependent deacetylation

31 March 2020

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Ordered nucleation and spreading of silenced chromatin in Saccharomyces cerevisiae.

31 March 2020

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Assembly of the SIR complex and its regulation by O-acetyl-ADP-ribose, a product of NAD-dependent histone deacetylation

31 March 2020

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Tethered Sir3p nucleates silencing at telomeres and internal loci in Saccharomyces cerevisiae

31 March 2020

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Sir3-dependent assembly of supramolecular chromatin structures in vitro

31 March 2020

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Cohabitation of insulators and silencing elements in yeast subtelomeric regions

31 March 2020

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Limitations of silencing at native yeast telomeres

31 March 2020

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SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast

31 March 2020

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Telomere looping permits gene activation by a downstream UAS in yeast

31 March 2020

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Telomere folding is required for the stable maintenance of telomere position effects in yeast

31 March 2020

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A methyltransferase targeting assay reveals silencer-telomere interactions in budding yeast

31 March 2020

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Evidence for silencing compartments within the yeast nucleus: a role for telomere proximity and Sir protein concentration in silencer-mediated repression

31 March 2020

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Silencing of genes at nontelomeric sites in yeast is controlled by sequestration of silencing factors at telomeres by Rap 1 protein

31 March 2020

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Heterochromatin formation involves changes in histone modifications over multiple cell generations

31 March 2020

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The contradictory definitions of heterochromatin: transcription and silencing.

31 March 2020

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Regulation of chromatin structure by site-specific histone H3 methyltransferases

31 March 2020

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Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly

31 March 2020

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Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain

31 March 2020

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Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins

31 March 2020

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Positive selection drives the evolution of rhino, a member of the heterochromatin protein 1 family in Drosophila

31 March 2020

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The hinge and chromo shadow domain impart distinct targeting of HP1-like proteins

31 March 2020

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Localization and phosphorylation of HP1 proteins during the cell cycle in mammalian cells

31 March 2020

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Cell cycle behavior of human HP1 subtypes: distinct molecular domains of HP1 are required for their centromeric localization during interphase and metaphase

31 March 2020

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The HP1 chromo shadow domain binds a consensus peptide pentamer

31 March 2020

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The mammalian heterochromatin protein 1 binds diverse nuclear proteins through a common motif that targets the chromoshadow domain

31 March 2020

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Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing

31 March 2020

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Self-interaction of heterochromatin protein 1 is required for direct binding to histone methyltransferase, SUV39H1.

31 March 2020

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Transitions in distinct histone H3 methylation patterns at the heterochromatin domain boundaries

31 March 2020

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Establishment and maintenance of a heterochromatin domain

31 March 2020

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The nucleation and maintenance of heterochromatin by a histone deacetylase in fission yeast.

31 March 2020

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RNAi-independent heterochromatin nucleation by the stress-activated ATF/CREB family proteins

31 March 2020

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Regulation of Swi6/HP1-dependent heterochromatin assembly by cooperation of components of the mitogen-activated protein kinase pathway and a histone deacetylase Clr6.

31 March 2020

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Sir2 regulates histone H3 lysine 9 methylation and heterochromatin assembly in fission yeast

31 March 2020

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Global effects on gene expression in fission yeast by silencing and RNA interference machineries.

31 March 2020

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Relationship between histone H3 lysine 9 methylation, transcription repression, and heterochromatin protein 1 recruitment.

31 March 2020

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In vivo dynamics of Swi6 in yeast: evidence for a stochastic model of heterochromatin.

31 March 2020

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Methylation-independent binding to histone H3 and cell cycle-dependent incorporation of HP1beta into heterochromatin

31 March 2020

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HP1 binding to native chromatin in vitro is determined by the hinge region and not by the chromodomain

31 March 2020

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Coordinated methyl and RNA binding is required for heterochromatin localization of mammalian HP1alpha

31 March 2020

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Heterochromatin formation in mammalian cells: interaction between histones and HP1 proteins

31 March 2020

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A role for DNA polymerase alpha in epigenetic control of transcriptional silencing in fission yeast

31 March 2020

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Maintenance of stable heterochromatin domains by dynamic HP1 binding

31 March 2020

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Modulation of heterochromatin protein 1 dynamics in primary Mammalian cells

31 March 2020

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High- and low-mobility populations of HP1 in heterochromatin of mammalian cells

31 March 2020

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A glue for heterochromatin maintenance: stable SUV39H1 binding to heterochromatin is reinforced by the SET domain

31 March 2020

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Maintenance of chromatin states: an open-and-shut case

31 March 2020

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RNA interference and heterochromatin in the fission yeast Schizosaccharomyces pombe

31 March 2020

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RNAi-directed assembly of heterochromatin in fission yeast

31 March 2020

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A Rik1-associated, cullin-dependent E3 ubiquitin ligase is essential for heterochromatin formation

31 March 2020

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Two novel proteins, dos1 and dos2, interact with rik1 to regulate heterochromatic RNA interference and histone modification

31 March 2020

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Ubiquitin ligase component Cul4 associates with Clr4 histone methyltransferase to assemble heterochromatin.

31 March 2020

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A chromodomain protein, Chp1, is required for the establishment of heterochromatin in fission yeast.

31 March 2020

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The Clr7 and Clr8 directionality factors and the Pcu4 cullin mediate heterochromatin formation in the fission yeast Schizosaccharomyces pombe

31 March 2020

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RITS acts in cis to promote RNA interference-mediated transcriptional and post-transcriptional silencing

31 March 2020

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Tails of intrigue: phosphorylation of RNA polymerase II mediates histone methylation

31 March 2020

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Tethering RITS to a nascent transcript initiates RNAi- and heterochromatin-dependent gene silencing.

31 March 2020

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Molecular hypotheses for position-effect variegation: anti-sense transcription and promoter occlusion

31 March 2020

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The genetics of position-effect variegation modifying loci in Drosophila melanogaster

31 March 2020

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Ectopic HP1 promotes chromosome loops and variegated silencing in Drosophila

31 March 2020

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Effects of tethering HP1 to euchromatic regions of the Drosophila genome.

31 March 2020

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Mechanisms of HP1-mediated gene silencing in Drosophila

31 March 2020

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Identification of in vivo DNA targets of chromatin proteins using tethered dam methyltransferase

31 March 2020

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cis-Acting determinants of heterochromatin formation on Drosophila melanogaster chromosome four

31 March 2020

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Double-stranded RNA-mediated silencing of genomic tandem repeats and transposable elements in the D. melanogaster germline

31 March 2020

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Cytogenetic and molecular aspects of position effect variegation in Drosophila. III. Continuous and discontinuous compaction of chromosomal material as a result of position effect variegation.

31 March 2020

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Expansions of transgene repeats cause heterochromatin formation and gene silencing in Drosophila.

31 March 2020

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Dosage-dependent modification of position-effect variegation in Drosophila

31 March 2020

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Heterochromatic silencing and HP1 localization in Drosophila are dependent on the RNAi machinery

31 March 2020

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The small RNA profile during Drosophila melanogaster development

31 March 2020

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Dissection of a natural RNA silencing process in the Drosophila melanogaster germ line

31 March 2020

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A pairing-sensitive element that mediates trans-inactivation is associated with the Drosophila brown gene.

31 March 2020

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Maintenance of heterochromatin by RNA interference of tandem repeats

31 March 2020

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Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites

31 March 2020

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Molecular Genetics of the Bithorax Complex in Drosophila melanogaster.

31 March 2020

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Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins

31 March 2020

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White gene expression, repressive chromatin domains and homeotic gene regulation in Drosophila

31 March 2020

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Genome-wide analysis of Polycomb targets in Drosophila melanogaster

31 March 2020

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Global nature of dynamic protein-chromatin interactions in vivo: three-dimensional genome scanning and dynamic interaction networks of chromatin proteins

31 March 2020

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Rap1-Sir4 binding independent of other Sir, yKu, or histone interactions initiates the assembly of telomeric heterochromatin in yeast

31 March 2020

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The origin recognition complex and Sir4 protein recruit Sir1p to yeast silent chromatin through independent interactions requiring a common Sir1p domain

31 March 2020

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Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: a molecular model for the formation of heterochromatin in yeast

31 March 2020

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Acetylation of the yeast histone H4 N terminus regulates its binding to heterochromatin protein SIR3.

31 March 2020

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Structure and function of the Saccharomyces cerevisiae Sir3 BAH domain

31 March 2020

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Genome-wide HP1 binding in Drosophila: developmental plasticity and genomic targeting signals

31 March 2020

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Distinct HP1 and Su(var)3-9 complexes bind to sets of developmentally coexpressed genes depending on chromosomal location

31 March 2020

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Physical and functional association of SU(VAR)3-9 and HDAC1 in Drosophila

31 March 2020

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A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin

31 March 2020

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Su(var) genes regulate the balance between euchromatin and heterochromatin in Drosophila

31 March 2020

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The JIL-1 histone H3S10 kinase regulates dimethyl H3K9 modifications and heterochromatic spreading in Drosophila

31 March 2020

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Conserved domains control heterochromatin localization and silencing properties of SU(VAR)3-7.

31 March 2020

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SU(VAR)3-7, a Drosophila heterochromatin-associated protein and companion of HP1 in the genomic silencing of position-effect variegation

31 March 2020

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Increased expression of Drosophila Su(var)3-7 triggers Su(var)3-9-dependent heterochromatin formation.

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRG1920

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Dimensions Publication ID

3 August 2017

1024772727

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