Evolution of promiscuous nuclear hormone receptors: LXR, FXR, VDR, PXR, and CAR (Q34550999)

3 August 2017

title

Evolution of promiscuous nuclear hormone receptors: LXR, FXR, VDR, PXR, and CAR (English)

1 reference

3 August 2017

4

1 reference

3 August 2017

Matthew D Krasowski

1

0 references

author name string

Ai Ni

series ordinal

2

1 reference

3 August 2017

Lee R Hagey

series ordinal

3

1 reference

3 August 2017

language of work or name

1 reference

6 July 2010

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Molecular and Cellular Endocrinology

3 August 2017

published in

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3 August 2017

volume

334

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3 August 2017

issue

1-2

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3 August 2017

page(s)

39-48

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Diversity of bile salts in fish and amphibians: evolution of a complex biochemical pathway

3 August 2017

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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The tangle of nuclear receptors that controls xenobiotic metabolism and transport: crosstalk and consequences.

7 July 2018

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Adaptability of the Vitamin D nuclear receptor to the synthetic ligand Gemini: remodelling the LBP with one side chain rotation

7 July 2018

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Identification of genes controlled by the pregnane X receptor by microarray analysis of mRNAs from pregnenolone 16alpha-carbonitrile-treated rats

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Identification of farnesoid X receptor beta as a novel mammalian nuclear receptor sensing lanosterol

7 July 2018

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The Draft Genome of Ciona intestinalis: Insights into Chordate and Vertebrate Origins

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Binding of ligands and activation of transcription by nuclear receptors.

7 July 2018

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Role of LXRs in control of lipogenesis

7 July 2018

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Ecdysone receptors and their biological actions

7 July 2018

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CXR, a chicken xenobiotic-sensing orphan nuclear receptor, is related to both mammalian pregnane X receptor (PXR) and constitutive androstane receptor (CAR)

7 July 2018

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The xenobiotic compound 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene is an agonist ligand for the nuclear receptor CAR

7 July 2018

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Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands

7 July 2018

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The crystal structure of the nuclear receptor for vitamin D bound to its natural ligand

7 July 2018

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The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution

7 July 2018

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Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

7 July 2018

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Bile acids: natural ligands for an orphan nuclear receptor

7 July 2018

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Identification of a nuclear receptor for bile acids

7 July 2018

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Androstane metabolites bind to and deactivate the nuclear receptor CAR-beta

7 July 2018

1 reference

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BXR, an embryonic orphan nuclear receptor activated by a novel class of endogenous benzoate metabolites.

7 July 2018

1 reference

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Sulfated compounds from marine organisms

7 July 2018

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The avian vitamin D receptors: primary structures and their origins

7 July 2018

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Ubiquitous receptor: a receptor that modulates gene activation by retinoic acid and thyroid hormone receptors

7 July 2018

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Natural occurrence and chemical synthesis of bile alcohols, higher bile acids, and short side chain bile acids.

7 July 2018

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Olfaction and gustation in fish: an overview

7 July 2018

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Identification of a nuclear receptor that is activated by farnesol metabolites

7 July 2018

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Comparative studies of bile salts, myxinol disulphate, the principal bile salt of hagfish (Myxinidae)

7 July 2018

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7 July 2018

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On the sterols of some ascidians

7 July 2018

1 reference

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Nuclear receptor DHR96 acts as a sentinel for low cholesterol concentrations in Drosophila melanogaster

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033471

The farnesoid X receptor FXRalpha/NR1H4 acquired ligand specificity for bile salts late in vertebrate evolution

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033471

Microarray-based compendium of hepatic gene expression profiles for prototypical ADME gene-inducing compounds in rats and mice in vivo

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033471

The DHR96 nuclear receptor regulates xenobiotic responses in Drosophila

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033471

A phylogenetic survey of biliary lipids in vertebrates

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033471

Loss of ancestral genes in the genomic evolution of Ciona intestinalis.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033471

Structural disorder in the complex of human pregnane X receptor and the macrolide antibiotic rifampicin

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033471

A structural basis for constitutive activity in the human CAR/RXRalpha heterodimer

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033471

The nuclear xenobiotic receptor CAR: structural determinants of constitutive activation and heterodimerization

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033471

A novel method for visualizing nuclear hormone receptor networks relevant to drug metabolism

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033471

T0901317 is a dual LXR/FXR agonist

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033471

Activators of the rat pregnane X receptor differentially modulate hepatic and intestinal gene expression

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033471

Molecular structure of the rat vitamin D receptor ligand binding domain complexed with 2-carbon-substituted vitamin D3 hormone analogues and a LXXLL-containing coactivator peptide

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033471

Vitamin K2 regulation of bone homeostasis is mediated by the steroid and xenobiotic receptor SXR.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033471

A genomewide survey of developmentally relevant genes in Ciona intestinalis. III. Genes for Fox, ETS, nuclear receptors and NFkappaB.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033471

Genetic profiling defines the xenobiotic gene network controlled by the nuclear receptor pregnane X receptor

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033471

Benzoate X receptors alpha and beta are pharmacologically distinct and do not function as xenobiotic receptors

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033471

Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and benzoate X receptor (BXR) define three pharmacologically distinct classes of nuclear receptors

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033471

FOR, a novel orphan nuclear receptor related to farnesoid X receptor

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033471

Identification of cDNAs encoding two subtypes of vitamin D receptor in flounder, Paralichthys olivaceus

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033471

Cloning and characterization of the vitamin D receptor from Xenopus laevis

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033471

Analysis of Nuclear Receptor Pseudogenes in Vertebrates: How the Silent Tell Their Stories

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033471

9 December 2018

Vitamin D and the skin

1 reference

12 December 2020

Oxysterol nuclear receptor LXRbeta regulates cholesterol homeostasis and contractile function in mouse uterus

1 reference

12 December 2020

Genome inventory and analysis of nuclear hormone receptors in Tetraodon nigroviridis

1 reference

12 December 2020

Crystal structure of the pregnane X receptor-estradiol complex provides insights into endobiotic recognition

1 reference

12 December 2020

Bile Acid secreted by male sea lamprey that acts as a sex pheromone

1 reference

12 December 2020

Identification and biosynthesis of steroid hormones in the gonads of Ciona intestinalis

1 reference

12 December 2020

10.1016/J.MCE.2010.06.016

Identifiers

DOI

1 reference

3 August 2017

1 reference

3 August 2017

1 reference