Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction (Q34534198)

2 August 2017

title

Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction (English)

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2 August 2017

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Giulio Maria Pasinetti

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object named as

Giulio M Pasinetti

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Lap Ho

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Jun Wang

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Weiping Qin

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Tianle Yang

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Zhong Zhao

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Linghong Chen

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Wei Zhao

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Meenakshisundaram Thiyagarajan

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Donal MacGrogan

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Joseph T Rodgers

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Pere Puigserver

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Junichi Sadoshima

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Haiteng Deng

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Steven Pedrini

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Samuel Gandy

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Anthony A Sauve

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language of work or name

English

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publication date

2 June 2006

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Journal of Biological Chemistry

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published in

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volume

281

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issue

31

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2 August 2017

page(s)

21745-21754

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The Sir2 family of protein deacetylases

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cites work

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Caloric restriction attenuates beta-amyloid neuropathology in a mouse model of Alzheimer's disease

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Caloric restriction attenuates Abeta-deposition in Alzheimer transgenic models

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Incidence of dementia and Alzheimer disease in 2 communities: Yoruba residing in Ibadan, Nigeria, and African Americans residing in Indianapolis, Indiana

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Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

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Potentiation of excitotoxicity in transgenic mice overexpressing neuronal cyclooxygenase-2

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Silent information regulator 2alpha, a longevity factor and class III histone deacetylase, is an essential endogenous apoptosis inhibitor in cardiac myocytes

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Modulation of statin-activated shedding of Alzheimer APP ectodomain by ROCK

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Cyclooxygenase (COX)-2 and COX-1 Potentiate β-Amyloid Peptide Generation through Mechanisms That Involve γ-Secretase Activity

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Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice.

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Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin

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Glia and their cytokines in progression of neurodegeneration

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SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling

21 January 2018

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Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration

21 January 2018

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hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

21 January 2018

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Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M602909200

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2 August 2017

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