Aph-2/Nicastrin: an essential component of gamma-secretase and regulator of Notch signaling and Presenilin localization (Q34520440)

2 August 2017

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title

Aph-2/Nicastrin: an essential component of gamma-secretase and regulator of Notch signaling and Presenilin localization (English)

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2 August 2017

Raphael Kopan

1

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Alison Goate

object named as

Alison Goate

series ordinal

2

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language of work or name

English

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publication date

1 January 2002

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2 August 2017

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2 August 2017

volume

33

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2 August 2017

issue

3

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2 August 2017

page(s)

321-324

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Pharmacological knock-down of the presenilin 1 heterodimer by a novel gamma -secretase inhibitor: implications for presenilin biology

2 August 2017

cites work

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https://api.crossref.org/works/10.1016/S0896-6273(02)00585-8

7 January 2021

A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

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https://api.crossref.org/works/10.1016/S0896-6273(02)00585-8

7 January 2021

Nicastrin binds to membrane-tethered Notch

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https://api.crossref.org/works/10.1016/S0896-6273(02)00585-8

7 January 2021

Nicastrin is required for Presenilin-mediated transmembrane cleavage in Drosophila

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(02)00585-8

7 January 2021

The amyloid precursor protein (APP)-cytoplasmic fragment generated by gamma-secretase is rapidly degraded but distributes partially in a nuclear fraction of neurones in culture

1 reference

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7 January 2021

The gamma -secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleus

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https://api.crossref.org/works/10.1016/S0896-6273(02)00585-8

7 January 2021

APH-1 is a multipass membrane protein essential for the Notch signaling pathway in Caenorhabditis elegans embryos

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(02)00585-8

7 January 2021

Nicastrin is required for gamma-secretase cleavage of the Drosophila Notch receptor

1 reference

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7 January 2021

A full genome scan for late onset Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(02)00585-8

7 January 2021

The intracellular domain of the beta-amyloid precursor protein is stabilized by Fe65 and translocates to the nucleus in a notch-like manner

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(02)00585-8

7 January 2021

APH-2/nicastrin functions in LIN-12/Notch signaling in the Caenorhabditis elegans somatic gonad.

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(02)00585-8

7 January 2021

Presenilin 1 is linked with gamma-secretase activity in the detergent solubilized state

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(02)00585-8

7 January 2021

Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(02)00585-8

7 January 2021

Drosophila nicastrin is essential for the intramembranous cleavage of notch

1 reference

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7 January 2021

A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1

1 reference

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7 January 2021

Effects of PS1 deficiency on membrane protein trafficking in neurons

1 reference

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7 January 2021

Cell surface presenilin-1 participates in the gamma-secretase-like proteolysis of Notch

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(02)00585-8

7 January 2021

Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(02)00585-8

7 January 2021

10.1016/S0896-6273(02)00585-8

Identifiers

DOI

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2 August 2017

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