CD4-induced activation in a soluble HIV-1 Env trimer (Q34510675)

2 August 2017

title

CD4-induced activation in a soluble HIV-1 Env trimer (English)

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2 August 2017

Jean-Philippe Julien

5

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Ian Andrew Wilson

7

object named as

Ian A Wilson

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2 August 2017

6

Rogier W Sanders

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2 August 2017

8

John P Moore

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2 August 2017

Miklos Guttman

1

1 reference

2 August 2017

Natalie K Garcia

2

1 reference

2 August 2017

Albert Cupo

3

1 reference

2 August 2017

Tsutomu Matsui

4

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2 August 2017

Kelly K Lee

9

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2 August 2017

publication date

12 June 2014

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2 August 2017

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2 August 2017

volume

22

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2 August 2017

issue

7

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2 August 2017

page(s)

974-984

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Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer

2 August 2017

cites work

1 reference

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Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer

7 July 2018

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Prefusion structure of trimeric HIV-1 envelope glycoprotein determined by cryo-electron microscopy

7 July 2018

1 reference

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Cleavage strongly influences whether soluble HIV-1 envelope glycoprotein trimers adopt a native-like conformation

7 July 2018

1 reference

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A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies

7 July 2018

1 reference

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Analysis of overlapped and noisy hydrogen/deuterium exchange mass spectra

7 July 2018

1 reference

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A functional interaction between gp41 and gp120 is observed for monomeric but not oligomeric, uncleaved HIV-1 Env gp140.

7 July 2018

1 reference

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Isolate-specific differences in the conformational dynamics and antigenicity of HIV-1 gp120.

7 July 2018

1 reference

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Structural characterization of cleaved, soluble HIV-1 envelope glycoprotein trimers

7 July 2018

1 reference

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Structural basis for diverse N-glycan recognition by HIV-1–neutralizing V1–V2–directed antibody PG16

7 July 2018

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Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors

7 July 2018

1 reference

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Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9.

7 July 2018

1 reference

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The highly conserved layer-3 component of the HIV-1 gp120 inner domain is critical for CD4-required conformational transitions.

7 July 2018

1 reference

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Fast photochemical oxidation of proteins and mass spectrometry follow submillisecond protein folding at the amino-acid level

7 July 2018

1 reference

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Structural mechanism of trimeric HIV-1 envelope glycoprotein activation

7 July 2018

1 reference

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Solution structure, conformational dynamics, and CD4-induced activation in full-length, glycosylated, monomeric HIV gp120

7 July 2018

1 reference

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Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops

7 July 2018

1 reference

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Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

7 July 2018

1 reference

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A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

7 July 2018

1 reference

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Tracking hydrogen/deuterium exchange at glycan sites in glycoproteins by mass spectrometry

7 July 2018

1 reference

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Broad neutralization coverage of HIV by multiple highly potent antibodies

7 July 2018

1 reference

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Structural mass spectrometry of proteins using hydroxyl radical based protein footprinting

7 July 2018

1 reference

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Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures

7 July 2018

1 reference

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Modification site localization scoring integrated into a search engine.

7 July 2018

1 reference

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Envelope glycans of immunodeficiency virions are almost entirely oligomannose antigens.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231881

Rational antibody-based HIV-1 vaccine design: current approaches and future directions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231881

Topological layers in the HIV-1 gp120 inner domain regulate gp41 interaction and CD4-triggered conformational transitions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231881

Hydrogen exchange mass spectrometry: what is it and what can it tell us?

7 July 2018

1 reference

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Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility

7 July 2018

1 reference

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Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target

7 July 2018

1 reference

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Molecular architecture of native HIV-1 gp120 trimers

7 July 2018

1 reference

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Glycosylation site-specific analysis of HIV envelope proteins (JR-FL and CON-S) reveals major differences in glycosylation site occupancy, glycoform profiles, and antigenic epitopes' accessibility

7 July 2018

1 reference

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Hydroxyl radical-mediated modification of proteins as probes for structural proteomics

7 July 2018

1 reference

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Purified, proteolytically mature HIV type 1 SOSIP gp140 envelope trimers

7 July 2018

1 reference

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Exploiting the defensive sugars of HIV-1 for drug and vaccine design

7 July 2018

1 reference

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Thermodynamics of binding of a low-molecular-weight CD4 mimetic to HIV-1 gp120.

7 July 2018

1 reference

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Semi-automated data processing of hydrogen exchange mass spectra using HX-Express

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231881

Secondary reactions and strategies to improve quantitative protein footprinting.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231881

UCSF Chimera--a visualization system for exploratory research and analysis

7 July 2018

1 reference

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Small-molecule inhibitors of HIV-1 entry block receptor-induced conformational changes in the viral envelope glycoproteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231881

Localized changes in the gp120 envelope glycoprotein confer resistance to human immunodeficiency virus entry inhibitors BMS-806 and #155.

7 July 2018

1 reference

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Biochemical and genetic characterizations of a novel human immunodeficiency virus type 1 inhibitor that blocks gp120-CD4 interactions

7 July 2018

1 reference

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A small molecule HIV-1 inhibitor that targets the HIV-1 envelope and inhibits CD4 receptor binding

7 July 2018

1 reference

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HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites

7 July 2018

1 reference

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Stabilization of the soluble, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1.

7 July 2018

1 reference

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The mannose-dependent epitope for neutralizing antibody 2G12 on human immunodeficiency virus type 1 glycoprotein gp120.

7 July 2018

1 reference

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Enhancing the proteolytic maturation of human immunodeficiency virus type 1 envelope glycoproteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231881

Energetics of the HIV gp120-CD4 binding reaction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231881

A recombinant human immunodeficiency virus type 1 envelope glycoprotein complex stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits is an antigenic mimic of the trimeric virion-associated structure

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231881

Core structure of gp41 from the HIV envelope glycoprotein

7 July 2018

1 reference

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Characterization of conserved human immunodeficiency virus type 1 gp120 neutralization epitopes exposed upon gp120-CD4 binding

7 July 2018

1 reference

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Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 A resolution

7 July 2018

1 reference

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Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells

7 July 2018

1 reference

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Escherichia coli expression, purification, and biological activity of a truncated soluble CD4.

7 July 2018

1 reference

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Human immunodeficiency virus type 1 gp120 envelope glycoprotein regions important for association with the gp41 transmembrane glycoprotein

7 July 2018

1 reference

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gamma-Ray-mediated oxidative labeling for detecting protein conformational changes by electrospray mass spectrometry

7 July 2018

1 reference

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Identification of N-phenyl-N'-(2,2,6,6-tetramethyl-piperidin-4-yl)-oxalamides as a new class of HIV-1 entry inhibitors that prevent gp120 binding to CD4.

27 October 2018

1 reference

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Quantitative mapping of glycoprotein micro-heterogeneity and macro-heterogeneity: an evaluation of mass spectrometry signal strengths using synthetic peptides and glycopeptides

27 October 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/24931470

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.STR.2014.05.001

1 reference

2 August 2017

1 reference

2 August 2017

1 reference