Ovary and fimbrial stem cells: biology, niche and cancer origins (Q34493156)

2 August 2017

title

Ovary and fimbrial stem cells: biology, niche and cancer origins (English)

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2 August 2017

Annie Ng

1

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2 August 2017

Nick Barker

series ordinal

2

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2 August 2017

language of work or name

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9 September 2015

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Nature Reviews Molecular Cell Biology

2 August 2017

published in

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2 August 2017

volume

16

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2 August 2017

issue

10

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2 August 2017

page(s)

625-638

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Proliferating cell nuclear antigen immunoreactivity in the ovarian surface epithelium of mice of varying ages and total lifetime ovulation number following ovulation

2 August 2017

cites work

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Dynamics of the primate ovarian surface epithelium during the ovulatory menstrual cycle

31 March 2020

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Gonadotropin-induced superovulation drives ovarian surface epithelia proliferation in CD1 mice

31 March 2020

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Altered expression of inflammation-associated genes in oviductal cells following follicular fluid exposure: implications for ovarian carcinogenesis.

31 March 2020

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Exposure of fallopian tube epithelium to follicular fluid mimics carcinogenic changes in precursor lesions of serous papillary carcinoma

31 March 2020

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The hormonal composition of follicular fluid and its implications for ovarian cancer pathogenesis

31 March 2020

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Identification of stem cells in small intestine and colon by marker gene Lgr5

31 March 2020

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Lgr5( ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro

31 March 2020

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Distinct stem cells contribute to mammary gland development and maintenance

31 March 2020

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Developmental stage and time dictate the fate of Wnt/β-catenin-responsive stem cells in the mammary gland

31 March 2020

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Multipotent and unipotent progenitors contribute to prostate postnatal development

31 March 2020

1 reference

Cellular heterogeneity in the mouse esophagus implicates the presence of a nonquiescent epithelial stem cell population

31 March 2020

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A single progenitor population switches behavior to maintain and repair esophageal epithelium

31 March 2020

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A single type of progenitor cell maintains normal epidermis.

31 March 2020

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Lgr5 marks cycling, yet long-lived, hair follicle stem cells.

31 March 2020

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Distinct contribution of stem and progenitor cells to epidermal maintenance

31 March 2020

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Defining the epithelial stem cell niche in skin

31 March 2020

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Interfollicular epidermal stem cells self-renew via autocrine Wnt signaling.

31 March 2020

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Stem cells, cancer, and cancer stem cells

31 March 2020

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Somatic stem cell heterogeneity: diversity in the blood, skin and intestinal stem cell compartments

31 March 2020

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Epithelial ovarian cancer stem cells: underlying complexity of a simple paradigm

31 March 2020

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Adult intestinal stem cells: critical drivers of epithelial homeostasis and regeneration

31 March 2020

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Dedifferentiation of committed epithelial cells into stem cells in vivo

31 March 2020

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Regeneration of multilineage skin epithelia by differentiated keratinocytes.

31 March 2020

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Ovarian cancer stem cells: Molecular concepts and relevance as therapeutic targets

31 March 2020

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Role of the stem cell niche in the pathogenesis of epithelial ovarian cancers

31 March 2020

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Normal ovarian surface epithelial label-retaining cells exhibit stem/progenitor cell characteristics

31 March 2020

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Identification of quiescent, stem-like cells in the distal female reproductive tract

31 March 2020

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Stem-like epithelial cells are concentrated in the distal end of the fallopian tube: a site for injury and serous cancer initiation

31 March 2020

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Long-term label retaining cells localize to distinct regions within the female reproductive epithelium

31 March 2020

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Lgr5 marks stem/progenitor cells in ovary and tubal epithelia

31 March 2020

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Ovarian surface epithelium at the junction area contains a cancer-prone stem cell niche

31 March 2020

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The origin of ovarian cancers--hypotheses and controversies

31 March 2020

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The origin of ovarian carcinomas: a unifying hypothesis

31 March 2020

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Ovulation and extra-ovarian origin of ovarian cancer

31 March 2020

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The origin of ovarian carcinomas: a developmental view

31 March 2020

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Ovarian tumorigenesis: a proposed model based on morphological and molecular genetic analysis

31 March 2020

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Early de novo ovarian cancer and cancer developing in benign ovarian lesions

31 March 2020

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The distal fallopian tube: a new model for pelvic serous carcinogenesis.

31 March 2020

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Dysplastic changes in prophylactically removed Fallopian tubes of women predisposed to developing ovarian cancer.

31 March 2020

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Developmental genetics of the female reproductive tract in mammals

31 March 2020

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Ovarian surface epitheliectomy in the non-human primate: continued cyclic ovarian function and limited epithelial replacement

31 March 2020

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Tissue Distribution of a Coelomic- Epithelium-Related Antigen Recognized by the Monoclonal Antibody OC125

31 March 2020

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A genetically engineered ovarian cancer mouse model based on fallopian tube transformation mimics human high-grade serous carcinoma development.

31 March 2020

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The impact of ovulation on fallopian tube epithelial cells: evaluating three hypotheses connecting ovulation and serous ovarian cancer

31 March 2020

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Production of offspring from a germline stem cell line derived from neonatal ovaries

31 March 2020

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Putative stem cells with an embryonic character isolated from the ovarian surface epithelium of women with no naturally present follicles and oocytes

31 March 2020

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Differentiation potential of germ line stem cells derived from the postnatal mouse ovary

31 March 2020

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Parthenogenetic embryo-like structures in the human ovarian surface epithelium cell culture in postmenopausal women with no naturally present follicles and oocytes

31 March 2020

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Oocyte formation by mitotically active germ cells purified from ovaries of reproductive-age women

31 March 2020

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Germline stem cells and follicular renewal in the postnatal mammalian ovary

31 March 2020

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Experimental evidence showing that no mitotically active female germline progenitors exist in postnatal mouse ovaries

31 March 2020

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No evidence for the presence of oogonia in the human ovary after their final clearance during the first two years of life

31 March 2020

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The primordial follicle reserve is not renewed after chemical or γ-irradiation mediated depletion

31 March 2020

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Female mice lack adult germ-line stem cells but sustain oogenesis using stable primordial follicles

31 March 2020

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Anchorage-independent culture of bovine granulosa cells: the effects of basic fibroblast growth factor and dibutyryl cAMP on cell division and differentiation

31 March 2020

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Marker genes identify three somatic cell types in the fetal mouse ovary

31 March 2020

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Temporal differences in granulosa cell specification in the ovary reflect distinct follicle fates in mice

31 March 2020

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Isolation, characterization, and in vitro and in vivo differentiation of putative thecal stem cells

31 March 2020

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Gene expression profiling supports the hypothesis that human ovarian surface epithelia are multipotent and capable of serving as ovarian cancer initiating cells

31 March 2020

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The stem-cell profile of ovarian surface epithelium is reproduced in the oviductal fimbriae, with increased stem-cell marker density in distal parts of the fimbriae

31 March 2020

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Aldehyde dehydrogenase as a marker for stem cells

31 March 2020

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Very long-term self-renewal of small intestine, colon, and hair follicles from cycling Lgr5 ve stem cells.

31 March 2020

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Developmental stage-specific contribution of LGR5( ) cells to basal and luminal epithelial lineages in the postnatal mammary gland

31 March 2020

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Lgr5( ve) stem/progenitor cells contribute to nephron formation during kidney development.

31 March 2020

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Temporal transcriptional profiling of somatic and germ cells reveals biased lineage priming of sexual fate in the fetal mouse gonad.

31 March 2020

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De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin

31 March 2020

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The Wnt receptor, Lrp5, is expressed by mouse mammary stem cells and is required to maintain the basal lineage

31 March 2020

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Canonical Wnt signals combined with suppressed TGFβ/BMP pathways promote renewal of the native human colonic epithelium

31 March 2020

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Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4

31 March 2020

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Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

31 March 2020

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Troy, a tumor necrosis factor receptor family member, interacts with lgr5 to inhibit wnt signaling in intestinal stem cells.

31 March 2020

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Differentiated Troy chief cells act as reserve stem cells to generate all lineages of the stomach epithelium

31 March 2020

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Female development in mammals is regulated by Wnt-4 signalling

31 March 2020

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Activation of beta-catenin signaling by Rspo1 controls differentiation of the mammalian ovary

31 March 2020

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R-spondin1 plays an essential role in ovarian development through positively regulating Wnt-4 signaling

31 March 2020

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Troy binding to lymphotoxin-alpha activates NF kappa B mediated transcription

31 March 2020

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Edar and Troy signalling pathways act redundantly to regulate initiation of hair follicle development

31 March 2020

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Uterine Wnt/beta-catenin signaling is required for implantation.

31 March 2020

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Chlamydia trachomatis disturbs epithelial tissue homeostasis in fallopian tubes via paracrine Wnt signaling

31 March 2020

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Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system

31 March 2020

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Sexually dimorphic development of the mammalian reproductive tract requires Wnt-7a

31 March 2020

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A family business: stem cell progeny join the niche to regulate homeostasis

31 March 2020

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Stem cell signaling. An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control

31 March 2020

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Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

31 March 2020

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Redundant sources of Wnt regulate intestinal stem cells and promote formation of Paneth cells

31 March 2020

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BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling

31 March 2020

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De novo crypt formation and juvenile polyposis on BMP inhibition in mouse intestine

31 March 2020

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Keratin 15 promoter targets putative epithelial stem cells in the hair follicle bulge.

31 March 2020

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Mammalian skin cell biology: at the interface between laboratory and clinic

31 March 2020

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Emerging interactions between skin stem cells and their niches

31 March 2020

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WNT signaling in ovarian follicle biology and tumorigenesis

31 March 2020

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Regulated expression of Wnts and Frizzleds at specific stages of follicular development in the rodent ovary

31 March 2020

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Wnt signaling in the ovary: identification and compartmentalized expression of wnt-2, wnt-2b, and frizzled-4 mRNAs

31 March 2020

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Expression and localization of secreted frizzled-related protein-4 in the rodent ovary: evidence for selective up-regulation in luteinized granulosa cells

31 March 2020

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β-catenin/Tcf-signaling appears to establish the murine ovarian surface epithelium (OSE) and remains active in selected postnatal OSE cells

31 March 2020

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TGF-β family signaling in stem cells

31 March 2020

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The epithelial-mesenchymal transition generates cells with properties of stem cells

31 March 2020

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Molecular pathways regulating EGF-induced epithelio-mesenchymal transition in human ovarian surface epithelium

31 March 2020

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Phenotypic Plasticity of the Ovarian Surface Epithelium: TGF-β1 Induction of Epithelial to Mesenchymal Transition (EMT) in Vitro

31 March 2020

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Identification of a putative autocrine bone morphogenetic protein-signaling pathway in human ovarian surface epithelium and ovarian cancer cells

31 March 2020

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Expression and action of transforming growth factor beta (TGFbeta1, TGFbeta2, TGFbeta3) in normal bovine ovarian surface epithelium and implications for human ovarian cancer

31 March 2020

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A functional bone morphogenetic protein system in the ovary

31 March 2020

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Smad 3 regulates proliferation of the mouse ovarian surface epithelium

31 March 2020

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The spatiotemporal expression pattern of the bone morphogenetic protein family in rat ovary cell types during the estrous cycle

31 March 2020

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Expression and action of transforming growth factor alpha in normal ovarian surface epithelium and ovarian cancer

31 March 2020

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Transforming growth factor alpha localization and role in surface epithelium of normal human ovaries and in ovarian carcinoma cells

31 March 2020

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Autocrine interactions of keratinocyte growth factor, hepatocyte growth factor, and kit-ligand in the regulation of normal ovarian surface epithelial cells

31 March 2020

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Hepatocyte growth factor induces rat ovarian surface epithelial cell mitosis or apoptosis depending on the presence or absence of an extracellular matrix

31 March 2020

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Expression and action of keratinocyte growth factor (KGF) in normal ovarian surface epithelium and ovarian cancer

31 March 2020

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Steroid hormone effects on the proliferation of human ovarian surface epithelium in vitro

31 March 2020

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Gonadotropin and steroid hormones stimulate proliferation of the rat ovarian surface epithelium.

31 March 2020

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Administration of gonadotropins stimulates proliferation of normal mouse ovarian surface epithelium

31 March 2020

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In vitro regulation of sheep ovarian surface epithelium (OSE) proliferation by local ovarian factors

31 March 2020

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Comparative immunohistochemical study of oestrogen and progesterone receptors in the fallopian tube and uterus at different stages of the menstrual cycle and the menopause

31 March 2020

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Insulin and insulin-like growth factor signaling increases proliferation and hyperplasia of the ovarian surface epithelium and decreases follicular integrity through upregulation of the PI3-kinase pathway

31 March 2020

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Three-dimensional ovarian organ culture as a tool to study normal ovarian surface epithelial wound repair

31 March 2020

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In vitro three-dimensional modeling of fallopian tube secretory epithelial cells.

31 March 2020

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In vitro three-dimensional modelling of human ovarian surface epithelial cells.

31 March 2020

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Isolation and in vitro expansion of human colonic stem cells.

31 March 2020

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Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

31 March 2020

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Wnt proteins are self-renewal factors for mammary stem cells and promote their long-term expansion in culture

31 March 2020

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Integrated genomic analyses of ovarian carcinoma

31 March 2020

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New insights into the pathogenesis of serous ovarian cancer and its clinical impact

31 March 2020

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Induction of ovarian cancer by defined multiple genetic changes in a mouse model system

31 March 2020

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17beta-estradiol accelerates tumor onset and decreases survival in a transgenic mouse model of ovarian cancer

31 March 2020

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Molecular and functional characteristics of ovarian surface epithelial cells transformed by KrasG12D and loss of Pten in a mouse model in vivo.

31 March 2020

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Animal models of ovarian cancer

31 March 2020

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Conditional inactivation of Brca1 in the mouse ovarian surface epithelium results in an increase in preneoplastic changes.

31 March 2020

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Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer

31 March 2020

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Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/beta-catenin and PI3K/Pten signaling pathways.

31 March 2020

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Perturbation of Rb, p53, and Brca1 or Brca2 cooperate in inducing metastatic serous epithelial ovarian cancer

31 March 2020

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Transformation of the fallopian tube secretory epithelium leads to high-grade serous ovarian cancer in Brca;Tp53;Pten models

31 March 2020

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High-grade serous ovarian cancer arises from fallopian tube in a mouse model

31 March 2020

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A mouse model for endometrioid ovarian cancer arising from the distal oviduct.

31 March 2020

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Crypt stem cells as the cells-of-origin of intestinal cancer

31 March 2020

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Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation

31 March 2020

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Bmi1 is expressed in vivo in intestinal stem cells

31 March 2020

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Functional genomics identifies five distinct molecular subtypes with clinical relevance and pathways for growth control in epithelial ovarian cancer

31 March 2020

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FZD7 drives in vitro aggressiveness in Stem-A subtype of ovarian cancer via regulation of non-canonical Wnt/PCP pathway.

31 March 2020

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A discrete population of squamocolumnar junction cells implicated in the pathogenesis of cervical cancer

31 March 2020

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Residual embryonic cells as precursors of a Barrett's-like metaplasia.

31 March 2020

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Roles of the ovarian surface epithelium in ovulation and carcinogenesis

31 March 2020

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Ovulation and the role of the ovarian surface epithelium

31 March 2020

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Evidence for a role of the ovarian surface epithelium in the ovulatory mechanism of the sheep: secretion of urokinase-type plasminogen activator

31 March 2020

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Reciprocal Interactions between Human Ovarian Surface Epithelial Cells and Adjacent Extracellular Matrix

31 March 2020

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Differential effects of RU486 and indomethacin on follicle rupture during the ovulatory process in the rat.

31 March 2020

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Whole ovary immunohistochemistry for monitoring cell proliferation and ovulatory wound repair in the mouse

31 March 2020

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Ovulation in the absence of the ovarian surface epithelium in the primate

31 March 2020

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Induction of proliferation in the primate ovarian surface epithelium in vivo.

31 March 2020

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Ovarian Surface Epithelium: Autonomous Production of Connective Tissue-Type Extracellular Matrix1

31 March 2020

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Proliferation in the normal FTE is a hallmark of the follicular phase, not BRCA mutation status.

31 March 2020

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Morphology and ultrastructure of fallopian tube epithelium at different stages of the menstrual cycle and menopause

31 March 2020

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Periovulatory multifocal mesothelial proliferation: a possible association with malignant transformation

31 March 2020

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Cyclic changes of the ovarian surface epithelium in the rat.

31 March 2020

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E-cadherin expression and bromodeoxyuridine incorporation during development of ovarian inclusion cysts in age-matched breeder and incessantly ovulated CD-1 mice

31 March 2020

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Incessant ovulation--a factor in ovarian neoplasia?

31 March 2020

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Ovarian surface epithelium as a source of ovarian cancers: unwarranted speculation or evidence-based hypothesis?

31 March 2020

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Lineage infidelity of epithelial ovarian cancers is controlled by HOX genes that specify regional identity in the reproductive tract

31 March 2020

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Intraepithelial carcinoma of the fimbria and pelvic serous carcinoma: Evidence for a causal relationship.

31 March 2020

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The tubal fimbria is a preferred site for early adenocarcinoma in women with familial ovarian cancer syndrome.

31 March 2020

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"Primary peritoneal" high-grade serous carcinoma is very likely metastatic from serous tubal intraepithelial carcinoma: assessing the new paradigm of ovarian and pelvic serous carcinogenesis and its implications for screening for ovarian cancer

31 March 2020

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A Pathologist's Road Map to Benign, Precancerous, and Malignant Intraepithelial Proliferations in the Fallopian Tube

31 March 2020

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TP53 mutations in serous tubal intraepithelial carcinoma and concurrent pelvic high‐grade serous carcinoma—evidence supporting the clonal relationship of the two lesions

31 March 2020

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Primary ex vivo cultures of human fallopian tube epithelium as a model for serous ovarian carcinogenesis.

31 March 2020

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Are All Pelvic (Nonuterine) Serous Carcinomas of Tubal Origin?

31 March 2020

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Ovarian surface epithelium: biology, endocrinology, and pathology

31 March 2020

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12 December 2020

Enrichment for living murine keratinocytes from the hair follicle bulge with the cell surface marker CD34.

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12 December 2020

Estrogen receptor localization in the female genital tract

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12 December 2020

Cyclic changes in ciliation, cell height, and mitotic activity in human tubal epithelium during reproductive life

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12 December 2020

Alginate Hydrogels for Three-Dimensional Organ Culture of Ovaries and Oviducts

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12 December 2020

Expression pattern of Wnt signaling components in the adult intestine

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12 December 2020

Female mice chimeric for expression of the simian virus 40 TAg under control of the MISIIR promoter develop epithelial ovarian cancer.

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12 December 2020

The mouse ovarian surface epithelium contains a population of LY6A (SCA-1) expressing progenitor cells that are regulated by ovulation-associated factors

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12 December 2020

Induction of carcinogenesis by concurrent inactivation of p53 and Rb1 in the mouse ovarian surface epithelium.

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12 December 2020

Expression and prognostic significance of TGF-beta isotypes, latent TGF-beta 1 binding protein, TGF-beta type I and type II receptors, and endoglin in normal ovary and ovarian neoplasms

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12 December 2020

Expression of epidermal growth factor and its receptor in the human ovary during follicular growth and regression

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12 December 2020

Coming into focus: the nonovarian origins of ovarian cancer.

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12 December 2020

Targeted disruption of the Wnt2 gene results in placentation defects

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12 December 2020

Identifiers

DOI

10.1038/NRM4056

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Dimensions Publication ID

2 August 2017

1028764275

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