The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1alpha-dependent mechanism. (Q34490597)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16452478 AND SRC:MED&resulttype=core&format=json

16 January 2020

title

The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1alpha-dependent mechanism (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16452478 AND SRC:MED&resulttype=core&format=json

16 January 2020

0 references

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16452478 AND SRC:MED&resulttype=core&format=json

16 January 2020

author name string

Mohammed S Ullah

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16452478 AND SRC:MED&resulttype=core&format=json

16 January 2020

Andrew J Davies

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16452478 AND SRC:MED&resulttype=core&format=json

16 January 2020

language of work or name

English

0 references

publication date

1 February 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16452478 AND SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

16 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16452478 AND SRC:MED&resulttype=core&format=json

16 January 2020

volume

281

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16452478 AND SRC:MED&resulttype=core&format=json

16 January 2020

issue

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16452478 AND SRC:MED&resulttype=core&format=json

16 January 2020

page(s)

9030-9037

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16452478 AND SRC:MED&resulttype=core&format=json

The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation

16 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1074/JBC.M511397200

Lactate transport in skeletal muscle - role and regulation of the monocarboxylate transporter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511397200

The SLC16 gene family?from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511397200

Characterization of the high-affinity monocarboxylate transporter MCT2 in Xenopus laevis oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511397200

Determination of transport kinetics of chick MCT3 monocarboxylate transporter from retinal pigment epithelium by expression in genetically modified yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511397200

The low-affinity monocarboxylate transporter MCT4 is adapted to the export of lactate in highly glycolytic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511397200

Characterisation of human monocarboxylate transporter 4 substantiates its role in lactic acid efflux from skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511397200

Lactic acid efflux from white skeletal muscle is catalyzed by the monocarboxylate transporter isoform MCT3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511397200

CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511397200

Basigin (CD147) is the target for organomercurial inhibition of monocarboxylate transporter isoforms 1 and 4: the ancillary protein for the insensitive MCT2 is EMBIGIN (gp70)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511397200

Fluorescence resonance energy transfer studies on the interaction between the lactate transporter MCT1 and CD147 provide information on the topology and stoichiometry of the complex in situ

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511397200

Exercise rapidly increases expression of the monocarboxylate transporters MCT1 and MCT4 in rat muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511397200

Role of hypoxia-induced anorexia and right ventricular hypertrophy on lactate transport and MCT expression in rat muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511397200

Comparison of hypoxia transcriptome in vitro with in vivo gene expression in human bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511397200

Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511397200

Hypoxia-inducible factor and its biomedical relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511397200

Regulation of angiogenesis by hypoxia: role of the HIF system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511397200

A novel hypoxia-inducible factor-independent hypoxic response regulating mammalian target of rapamycin and its targets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511397200

The human monocarboxylate transporter, MCT1: genomic organization and promoter analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511397200

Genomic structure and developmental expression of the chicken nonocarboxylate transporter MCT3 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511397200

Transport characteristics of HL-1 cells: a new model for the study of adenosine physiology in cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511397200

Cloning and sequencing of four new mammalian monocarboxylate transporter (MCT) homologues confirms the existence of a transporter family with an ancient past

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511397200

Effects of transition metals on the expression of the erythropoietin gene: further evidence that the oxygen sensor is a heme protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511397200

Identification of hypoxia-inducible factor 1 ancillary sequence and its function in vascular endothelial growth factor gene induction by hypoxia and nitric oxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511397200

The HIF pathway in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511397200

Cytosolic action of thyroid hormone leads to induction of hypoxia-inducible factor-1alpha and glycolytic genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M511397200