Killing the messenger: new insights into nonsense-mediated mRNA decay (Q34487265)

2 August 2017

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title

Killing the messenger: new insights into nonsense-mediated mRNA decay. (English)

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2 August 2017

Peter H Byers

1

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2 August 2017

language of work or name

English

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publication date

1 January 2002

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Journal of Clinical Investigation

2 August 2017

published in

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2 August 2017

volume

109

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2 August 2017

issue

1

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2 August 2017

page(s)

3-6

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Magoh, a human homolog of Drosophila mago nashi protein, is a component of the splicing-dependent exon-exon junction complex

2 August 2017

cites work

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Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20

6 July 2018

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Role of the nonsense-mediated decay factor hUpf3 in the splicing-dependent exon-exon junction complex

6 July 2018

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6 July 2018

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Mammalian heat shock p70 and histone H4 transcripts, which derive from naturally intronless genes, are immune to nonsense-mediated decay

6 July 2018

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Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon

6 July 2018

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The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions

6 July 2018

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Pre-mRNA splicing imprints mRNA in the nucleus with a novel RNA-binding protein that persists in the cytoplasm

6 July 2018

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The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans

6 July 2018

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Characterization of the biochemical properties of the human Upf1 gene product that is involved in nonsense-mediated mRNA decay

6 July 2018

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Tracking COL1A1 RNA in osteogenesis imperfecta. splice-defective transcripts initiate transport from the gene but are retained within the SC35 domain

6 July 2018

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The acute myeloid leukemia-associated protein, DEK, forms a splicing-dependent interaction with exon-product complexes

6 July 2018

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Purification and characterization of human RNPS1: a general activator of pre-mRNA splicing

6 July 2018

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Redefinition of exon 7 in the COL1A1 gene of type I collagen by an intron 8 splice-donor-site mutation in a form of osteogenesis imperfecta: influence of intron splice order on outcome of splice-site mutation

6 July 2018

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Intron function in the nonsense-mediated decay of beta-globin mRNA: indications that pre-mRNA splicing in the nucleus can influence mRNA translation in the cytoplasm

6 July 2018

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A coactivator of pre-mRNA splicing

6 July 2018

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A splicing-dependent regulatory mechanism that detects translation signals

6 July 2018

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Evidence to implicate translation by ribosomes in the mechanism by which nonsense codons reduce the nuclear level of human triosephosphate isomerase mRNA.

6 July 2018

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Introns are cis effectors of the nonsense-codon-mediated reduction in nuclear mRNA abundance

6 July 2018

1 reference

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A regulatory mechanism that detects premature nonsense codons in T-cell receptor transcripts in vivo is reversed by protein synthesis inhibitors in vitro

6 July 2018

1 reference

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6 July 2018

Identifiers

DOI

10.1172/JCI0214841

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2 August 2017

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2 August 2017

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