Lemur Tyrosine Kinase 2, a novel target in prostate cancer therapy (Q34477815)

2 August 2017

title

Lemur Tyrosine Kinase 2, a novel target in prostate cancer therapy (English)

1 reference

2 August 2017

1 reference

Kalpit Shah

1

1 reference

2 August 2017

Neil A Bradbury

series ordinal

2

1 reference

2 August 2017

language of work or name

English

0 references

publication date

1 June 2015

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2 August 2017

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2 August 2017

volume

6

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2 August 2017

issue

16

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2 August 2017

page(s)

14233-14246

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Synonymous codon usage affects the expression of wild type and F508del CFTR.

2 August 2017

cites work

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6 July 2018

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Mcl-1 promotes lung cancer cell migration by directly interacting with VDAC to increase mitochondrial Ca2 uptake and reactive oxygen species generation

6 July 2018

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Enrichment of prostate cancer stem cells from primary prostate cancer cultures of biopsy samples

6 July 2018

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Prostate cancer (PCa) risk variants and risk of fatal PCa in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium

6 July 2018

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6 July 2018

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Determination of the membrane topology of lemur tyrosine kinase 2 (LMTK2) by fluorescence protease protection

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546463

Identification of kinases regulating prostate cancer cell growth using an RNAi phenotypic screen

6 July 2018

1 reference

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Synergistic activity of the mTOR inhibitor ridaforolimus and the antiandrogen bicalutamide in prostate cancer models

6 July 2018

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Recruitment of the endosomal WASH complex is mediated by the extended ‘tail’ of Fam21 binding to the retromer protein Vps35

6 July 2018

1 reference

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Characterization of sphere-propagating cells with stem-like properties from DU145 prostate cancer cells.

6 July 2018

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CDK9 regulates AR promoter selectivity and cell growth through serine 81 phosphorylation

6 July 2018

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Drug resistance in metastatic castration-resistant prostate cancer

6 July 2018

1 reference

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Expression of the nuclear transport protein importin ß-1 and its association with the neurokinin 3 receptor in the rat hypothalamus following acute hyperosmotic challenge

6 July 2018

1 reference

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Alterations in LMTK2, MSMB and HNF1B gene expression are associated with the development of prostate cancer

6 July 2018

1 reference

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Isolation, cultivation and characterization of adult murine prostate stem cells

6 July 2018

1 reference

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FKBP51 promotes assembly of the Hsp90 chaperone complex and regulates androgen receptor signaling in prostate cancer cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546463

FKBP51 and Cyp40 are positive regulators of androgen-dependent prostate cancer cell growth and the targets of FK506 and cyclosporin A.

6 July 2018

1 reference

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Androgen receptor phosphorylation and activity are regulated by an association with protein phosphatase 1

6 July 2018

1 reference

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Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifs

6 July 2018

1 reference

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Estrogen receptor alpha/beta, AIB1, and TIF2 in colorectal carcinogenesis: do coregulators have prognostic significance?

6 July 2018

1 reference

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Six classes of nuclear localization signals specific to different binding grooves of importin alpha

6 July 2018

1 reference

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Design of peptide inhibitors for the importin alpha/beta nuclear import pathway by activity-based profiling

6 July 2018

1 reference

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BREK/LMTK2 is a myosin VI-binding protein involved in endosomal membrane trafficking

6 July 2018

1 reference

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Multiple newly identified loci associated with prostate cancer susceptibility

6 July 2018

1 reference

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Myosin VI and its interacting protein LMTK2 regulate tubule formation and transport to the endocytic recycling compartment.

6 July 2018

1 reference

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Androgen deprivation therapy in the treatment of advanced prostate cancer

6 July 2018

1 reference

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Direct observation of individual endogenous protein complexes in situ by proximity ligation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546463

Peptide microarray analysis of substrate specificity of the transmembrane Ser/Thr kinase KPI-2 reveals reactivity with cystic fibrosis transmembrane conductance regulator and phosphorylase

6 July 2018

1 reference

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Stem cells in prostate cancer: resolving the castrate-resistant conundrum and implications for hormonal therapy

6 July 2018

1 reference

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Stress kinase signaling regulates androgen receptor phosphorylation, transcription, and localization

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546463

Prostate specific antigen gene regulation by androgen receptor

6 July 2018

1 reference

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Analysis and prediction of leucine-rich nuclear export signals

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546463

Androgen receptor in prostate cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546463

Molecular determinants of resistance to antiandrogen therapy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546463

Gene expression analysis of human prostate carcinoma during hormonal therapy identifies androgen-responsive genes and mechanisms of therapy resistance

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546463

Identification of a novel, membrane-associated neuronal kinase, cyclin-dependent kinase 5/p35-regulated kinase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546463

National Comprehensive Cancer Network guidelines for the management of prostate cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546463

Role of the estrogen receptor coactivator AIB1 (SRC-3) and HER-2/neu in tamoxifen resistance in breast cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546463

The role of the androgen receptor in prostate cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546463

A novel transmembrane Ser/Thr kinase complexes with protein phosphatase-1 and inhibitor-2

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546463

Generation and characterization of androgen receptor knockout (ARKO) mice: an in vivo model for the study of androgen functions in selective tissues

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546463

The development of androgen-independent prostate cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546463

Dysregulated expression of androgen-responsive and nonresponsive genes in the androgen-independent prostate cancer xenograft model CWR22-R1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546463

Stem cell features of benign and malignant prostate epithelial cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546463

The nuclear receptor superfamily: the second decade

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546463

Nuclear import of the human androgen receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546463

Receptor-mediated transcytosis of IgA in MDCK cells is via apical recycling endosomes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546463

Molecular mechanisms of action of steroid/thyroid receptor superfamily members

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546463

In vivo amplification of the androgen receptor gene and progression of human prostate cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546463

Keratin expression: a measure of phenotypic modulation of human prostatic epithelial cells by growth inhibitory factors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546463

Molecular Cloning of Human and Rat Complementary DNA Encoding Androgen Receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546463

Molecular characterisation, expression and localisation of human neurokinin‐3 receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546463

Association of TET2, LMTK2 and FAM84B gene expression with prostate cancer risk in Chinese patients

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546463

New insights on regulation of LMTK2, a membrane kinase integrating pathways central to neurodegeneration

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546463

Cdk5/p35 phosphorylates lemur tyrosine kinase‐2 to regulate protein phosphatase‐1C phosphorylation and activity

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546463

HER2/neu kinase-dependent modulation of androgen receptor function through effects on DNA binding and stability

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546463

Microarray analysis of prostate cancer progression to reduced androgen dependence: studies in unique models contrasts early and late molecular events

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546463

Overexpression, amplification, and androgen regulation of TPD52 in prostate cancer

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546463

MAP kinase/estrogen receptor cross-talk enhances estrogen-mediated signaling and tumor growth but does not confer tamoxifen resistance.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546463

Outcome predictions for patients with metastatic prostate cancer.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546463

release_ih56iaxzqbdlxbcfe2txnuawym

27 October 2018

Identifiers

DOI

10.18632/ONCOTARGET.3899

0 references

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ih56iaxzqbdlxbcfe2txnuawym

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

4546463

1 reference

2 August 2017

1 reference