Immunoglobulin variable-region gene usage in systemic autoimmune diseases (Q34474688)

2 August 2017

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title

Immunoglobulin variable-region gene usage in systemic autoimmune diseases (English)

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2 August 2017

Dörner T

1

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2 August 2017

Lipsky PE

series ordinal

2

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2 August 2017

publication date

1 December 2001

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2 August 2017

published in

Arthritis & Rheumatology

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2 August 2017

volume

44

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2 August 2017

issue

12

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2 August 2017

page(s)

2715-2727

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Somatic generation of antibody diversity

2 August 2017

cites work

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21 January 2018

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21 January 2018

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Analysis of immunoglobulin variable region genes from human IgG anti-DNA hybridomas

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Analysis of heavy and light chain pairings indicates that receptor editing shapes the human antibody repertoire

21 January 2018

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21 January 2018

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Somatic mutations in the variable regions of a human IgG anti-double-stranded DNA autoantibody suggest a role for antigen in the induction of systemic lupus erythematosus

21 January 2018

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21 January 2018

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Lifetime of plasma cells in the bone marrow

21 January 2018

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Memory B-cell persistence is independent of persisting immunizing antigen.

21 January 2018

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Immunoglobulin kappa chain receptor editing in systemic lupus erythematosus

21 January 2018

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Use of immunoglobulin variable-region genes by normal subjects and patients with systemic lupus erythematosus

21 January 2018

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21 January 2018

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21 January 2018

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Light chain editing in kappa-deficient animals: a potential mechanism of B cell tolerance

21 January 2018

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21 January 2018

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Receptor editing in self-reactive bone marrow B cells

21 January 2018

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Revising B cell receptors

21 January 2018

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RAG1 and RAG2 expression by B cell subsets from human tonsil and peripheral blood.

21 January 2018

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Antigen-independent appearance of recombination activating gene (RAG)-positive bone marrow B cells in the spleens of immunized mice

21 January 2018

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Lymphocytes rearrange, edit and revise their antigen receptors to be useful yet safe

21 January 2018

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Receptor editing, immune diversification, and self-tolerance

21 January 2018

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Characterization of a germline Vk gene encoding cationic anti-DNA antibody and role of receptor editing for development of the autoantibody in patients with systemic lupus erythematosus

21 January 2018

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Receptor editing: an approach by autoreactive B cells to escape tolerance

21 January 2018

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Analysis of the VKI Family: Germline Genes from an SLE Patient and Expressed Autoantibodies

21 January 2018

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Lupus-specific antibodies reveal an altered pattern of somatic mutation

21 January 2018

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Repertoire cloning of lupus anti-DNA autoantibodies

21 January 2018

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Genetic, structural and functional properties of an IgG DNA-binding monoclonal antibody from a lupus patient with nephritis

21 January 2018

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Lupus/Sjögren's autoantibody specificities in sera with paraproteins

21 January 2018

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Preferential utilization of a novel V lambda 3 gene in monoclonal rheumatoid factors derived from the synovial cells of rheumatoid arthritis patients

21 January 2018

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Human rheumatoid factors with restrictive specificity for rabbit immunoglobulin G: auto- and multi-reactivity, diverse VH gene segment usage and preferential usage of V lambda IIIb

21 January 2018

1 reference

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The production, binding characteristics and sequence analysis of four human IgG monoclonal antiphospholipid antibodies

21 January 2018

1 reference

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Light chain variable (VL) sequences of rheumatoid factors (RF) in patients with primary Sjögren's syndrome (pSS): moderate contribution of somatic hypermutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1529-0131(200112)44:12<2715::AID-ART458>3.0.CO;2-L

Immunoglobulin heavy chain variable region gene replacement As a mechanism for receptor revision in rheumatoid arthritis synovial tissue B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1529-0131(200112)44:12<2715::AID-ART458>3.0.CO;2-L

Comparable heavy and light chain pairings in normal and systemic lupus erythematosus IgG( ) B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1529-0131(200112)44:12<2715::AID-ART458>3.0.CO;2-L

Structural analysis of VH4-21 encoded human IgM allo- and autoantibodies against red blood cells

21 January 2018

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Three-dimensional structure of the Fab from a human IgM cold agglutinin

21 January 2018

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Sequence analysis of V(4-34)-encoded antibodies from single B cells of two patients with systemic lupus erythematosus (SLE).

21 January 2018

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https://api.crossref.org/works/10.1002/1529-0131(200112)44:12<2715::AID-ART458>3.0.CO;2-L

Correlation of 9G4 idiotope with disease activity in patients with systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1529-0131(200112)44:12<2715::AID-ART458>3.0.CO;2-L

Comparative characteristics of mu chain and alpha chain transcripts expressed by individual tonsil plasma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1529-0131(200112)44:12<2715::AID-ART458>3.0.CO;2-L

Antigen-driven clonal proliferation of B cells within the target tissue of an autoimmune disease. The salivary glands of patients with Sjögren's syndrome

21 January 2018

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https://api.crossref.org/works/10.1002/1529-0131(200112)44:12<2715::AID-ART458>3.0.CO;2-L

Molecular characterization of a somatically mutated anti-DNA antibody bearing two systemic lupus erythematosus-related idiotypes

21 January 2018

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DNA Double-Strand Breaks in Immunoglobulin Genes Undergoing Somatic Hypermutation

21 January 2018

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The double edged sword of the immune response: mutational analysis of a murine anti-pneumococcal, anti-DNA antibody

21 January 2018

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Immunization with a Peptide Surrogate for Double-stranded DNA (dsDNA) Induces Autoantibody Production and Renal Immunoglobulin Deposition

21 January 2018

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Pathogenic autoantibodies are routinely generated during the response to foreign antigen: a paradigm for autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1529-0131(200112)44:12<2715::AID-ART458>3.0.CO;2-L

VH-gene representation in autoantibodies reflects the normal human B-cell repertoire

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1529-0131(200112)44:12<2715::AID-ART458>3.0.CO;2-L

The role of somatic mutation in the pathogenic anti-DNA response

21 January 2018

1 reference

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The CDR1 sequences of a major proportion of human germline Ig VH genes are inherently susceptible to amino acid replacement

21 January 2018

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https://api.crossref.org/works/10.1002/1529-0131(200112)44:12<2715::AID-ART458>3.0.CO;2-L

It's not the same old lupus or Sjögren's any more: one hundred new insights, approaches, and options since 1990.

21 January 2018

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Targeting and selection of mutations in human Vlambda rearrangements

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1529-0131(200112)44:12<2715::AID-ART458>3.0.CO;2-L

10.1002/1529-0131(200112)44:12<2715::AID-ART458>3.0.CO;2-L

21 January 2018

Identifiers

DOI

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2 August 2017

1 reference