The PDZ protein GIPC regulates trafficking of the LPA1 receptor from APPL signaling endosomes and attenuates the cell's response to LPA. (Q34474291)

2 August 2017

title

The PDZ protein GIPC regulates trafficking of the LPA1 receptor from APPL signaling endosomes and attenuates the cell's response to LPA. (English)

1 reference

2 August 2017

Tal Varsano

1

0 references

Marilyn Farquhar

series ordinal

5

object named as

Marilyn G Farquhar

1 reference

2 August 2017

Vanessa Taupin

2

1 reference

2 August 2017

Lixia Guo

series ordinal

3

1 reference

2 August 2017

Oscar Y Baterina

series ordinal

4

1 reference

2 August 2017

language of work or name

English

0 references

publication date

8 November 2012

1 reference

2 August 2017

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2 August 2017

volume

7

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2 August 2017

issue

11

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2 August 2017

page(s)

e49227

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Creative Commons Attribution 4.0 International

2 August 2017

copyright license

start time

8 November 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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GIPC is recruited by APPL to peripheral TrkA endosomes and regulates TrkA trafficking and signaling

6 July 2018

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APPL1 associates with TrkA and GIPC1 and is required for nerve growth factor-mediated signal transduction

6 July 2018

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Binding of internalized receptors to the PDZ domain of GIPC/synectin recruits myosin VI to endocytic vesicles

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6 July 2018

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6 July 2018

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Lysophosphatidic acid and autotaxin stimulate cell motility of neoplastic and non-neoplastic cells through LPA1.

6 July 2018

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6 July 2018

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Interactions of GIPC with Dopamine D2, D3but not D4Receptors Define a Novel Mode of Regulation of G Protein-coupled Receptors

6 July 2018

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GIPC Binds to the Human Lutropin Receptor (hLHR) through an Unusual PDZ Domain Binding Motif, and It Regulates the Sorting of the Internalized Human Choriogonadotropin and the Density of Cell Surface hLHR

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Assessment of agonism at G-protein coupled receptors by phosphatidic acid and lysophosphatidic acid in human embryonic kidney 293 cells

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PDZ domain protein GIPC interacts with the cytoplasmic tail of melanosomal membrane protein gp75 (tyrosinase-related protein-1)

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Functional comparisons of the lysophosphatidic acid receptors, LP(A1)/VZG-1/EDG-2, LP(A2)/EDG-4, and LP(A3)/EDG-7 in neuronal cell lines using a retrovirus expression system

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1 reference

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1 reference

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1 reference

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Identification of a chromosome 3p14.3-21.1 gene, APPL, encoding an adaptor molecule that interacts with the oncoprotein-serine/threonine kinase AKT2

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1 reference

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1 reference

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1 reference

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1 reference

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https://api.crossref.org/works/10.1371/JOURNAL.PONE.0049227

A requirement for membrane cholesterol in the beta-arrestin- and clathrin-dependent endocytosis of LPA1 lysophosphatidic acid receptors

21 January 2018

1 reference

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Functional analysis of cell adhesion: quantitation of cell-matrix attachment.

21 January 2018

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Endoglin promotes transforming growth factor beta-mediated Smad 1/5/8 signaling and inhibits endothelial cell migration through its association with GIPC.

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10.1371/JOURNAL.PONE.0049227

21 January 2018

Identifiers

DOI

1 reference

2 August 2017

0 references

1 reference

2 August 2017

1 reference