Binding site asymmetry in human transthyretin: insights from a joint neutron and X-ray crystallographic analysis using perdeuterated protein (Q34473216)

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English	Binding site asymmetry in human transthyretin: insights from a joint neutron and X-ray crystallographic analysis using perdeuterated protein	scientific article

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24 February 2020

Binding site asymmetry in human transthyretin: insights from a joint neutron and X-ray crystallographic analysis using perdeuterated protein (English)

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24 February 2020

Matthew P Blakeley

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24 February 2020

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Melina Haupt

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24 February 2020

Stuart J Fisher

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24 February 2020

Sax A Mason

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24 February 2020

Jon B Cooper

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24 February 2020

Edward P Mitchell

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24 February 2020

V Trevor Forsyth

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24 February 2020

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21 October 2014

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24 February 2020

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24 February 2020

1

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24 February 2020

Pt 6

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24 February 2020

429-438

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24 February 2020

L-Arabinose binding, isomerization, and epimerization by D-xylose isomerase: X-ray/neutron crystallographic and molecular simulation study

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Heme enzymes. Neutron cryo-crystallography captures the protonation state of ferryl heme in a peroxidase

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Diflunisal for ATTR cardiac amyloidosis

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Nearly 200 X-ray crystal structures of transthyretin: what do they tell us about this protein and the design of drugs for TTR amyloidoses?

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6 July 2018

Hydrogen-bond network and pH sensitivity in transthyretin: Neutron crystal structure of human transthyretin

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6 July 2018

Preliminary neutron crystallographic study of human transthyretin

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6 July 2018

Familial amyloid polyneuropathy

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6 July 2018

Identification of the elusive hydronium ion exchanging roles with a proton in an enzyme at lower pH values

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6 July 2018

Overview of the CCP4 suite and current developments

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6 July 2018

Bilayer-mediated clustering and functional interaction of MscL channels.

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6 July 2018

The active site protonation states of perdeuterated Toho-1 β-lactamase determined by neutron diffraction support a role for Glu166 as the general base in acylation

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6 July 2018

Variation in amount of wild-type transthyretin in different fibril and tissue types in ATTR amyloidosis

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6 July 2018

Trapping of palindromic ligands within native transthyretin prevents amyloid formation

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6 July 2018

Joint X-ray and neutron refinement with phenix.refine

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6 July 2018

Metal Ion Roles and the Movement of Hydrogen during Reaction Catalyzed by D-Xylose Isomerase: A Joint X-Ray and Neutron Diffraction Study

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6 July 2018

Features and development of Coot

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Structure-based design of kinetic stabilizers that ameliorate the transthyretin amyloidoses

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6 July 2018

A Substructure Combination Strategy To Create Potent and Selective Transthyretin Kinetic Stabilizers That Prevent Amyloidogenesis and Cytotoxicity

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6 July 2018

Neutron diffraction studies of a class A beta-lactamase Toho-1 E166A/R274N/R276N triple mutant

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The ID23-2 structural biology microfocus beamline at the ESRF.

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6 July 2018

Evolutionary changes to transthyretin: structure-function relationships

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6 July 2018

Perdeuteration, purification, crystallization and preliminary neutron diffraction of an ocean pout type III antifreeze protein.

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Pathogenesis of and therapeutic strategies to ameliorate the transthyretin amyloidoses

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A molecular correlate of clinicopathology in transthyretin amyloidosis

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Significance of transthyretin in protein metabolism

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Transthyretin: a review from a structural perspective.

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6 July 2018

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The beta-slip: a novel concept in transthyretin amyloidosis

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6 July 2018

A comparative analysis of 23 structures of the amyloidogenic protein transthyretin

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6 July 2018

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6 July 2018

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21 January 2018

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21 January 2018

Amyloid fibril composition is related to the phenotype of hereditary transthyretin V30M amyloidosis

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21 January 2018

Stability and fibril formation properties of human and fish transthyretin, and of the Escherichia coli transthyretin-related protein.

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Identification of a subunit interface in transthyretin amyloid fibrils: evidence for self-assembly from oligomeric building blocks

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21 January 2018

Kinetic stabilization of an oligomeric protein by a single ligand binding event

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21 January 2018

Structural basis of negative cooperativity in transthyretin.

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27 October 2018

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A high angle neutron fibre diffraction study of the hydration of the A conformation of the DNA double helix

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Looking at hydrogen bonds in cellulose

1 reference

https://pubmed.ncbi.nlm.nih.gov/25485123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutron structure analysis using the IBARAKI biological crystal diffractometer (iBIX) at J-PARC

1 reference

https://pubmed.ncbi.nlm.nih.gov/25485123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wild-type transthyretin significantly contributes to the formation of amyloid fibrils in familial amyloid polyneuropathy patients with amyloidogenic transthyretin Val30Met

1 reference

https://pubmed.ncbi.nlm.nih.gov/25485123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutron fibre diffraction study of DNA hydration

1 reference

https://pubmed.ncbi.nlm.nih.gov/25485123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A high-angle neutron fibre diffraction study of the hydration of deuterated A-DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/25485123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1107/S2052252514021113

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25485123 AND SRC:MED&resulttype=core&format=json

24 February 2020

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24 February 2020

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24 February 2020

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