Molecular basis for mid-region amyloid-β capture by leading Alzheimer's disease immunotherapies (Q34472054)

2 August 2017

title

Molecular basis for mid-region amyloid-β capture by leading Alzheimer's disease immunotherapies (English)

1 reference

2 August 2017

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1 reference

Michael W Parker

3

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author name string

Gabriela A N Crespi

series ordinal

1

1 reference

2 August 2017

Stefan J Hermans

series ordinal

2

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2 August 2017

Luke A Miles

series ordinal

4

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2 August 2017

language of work or name

English

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publication date

16 April 2015

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2 August 2017

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2 August 2017

volume

5

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2 August 2017

page(s)

9649

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Creative Commons Attribution 4.0 International

2 August 2017

copyright license

start time

16 April 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Crystal structure reveals conservation of amyloid-β conformation recognized by 3D6 following humanization to bapineuzumab

6 July 2018

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Do current therapeutic anti-Aβ antibodies for Alzheimer's disease engage the target?

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X-ray Crystallographic Structures of Trimers and Higher-Order Oligomeric Assemblies of a Peptide Derived from Aβ 17–36

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Crystallization and preliminary X-ray diffraction analysis of the Fab portion of the Alzheimer's disease immunotherapy candidate bapineuzumab complexed with amyloid-β

6 July 2018

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Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease

6 July 2018

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Passive anti-amyloid immunotherapy in Alzheimer's disease: What are the most promising targets?

6 July 2018

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Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study

6 July 2018

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Bapineuzumab captures the N-terminus of the Alzheimer's disease amyloid-beta peptide in a helical conformation

6 July 2018

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6 July 2018

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Structural basis of C-terminal β-amyloid peptide binding by the antibody ponezumab for the treatment of Alzheimer's disease

6 July 2018

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Alzheimer's Prevention Initiative: a plan to accelerate the evaluation of presymptomatic treatments

6 July 2018

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Gantenerumab: a novel human anti-Aβ antibody demonstrates sustained cerebral amyloid-β binding and elicits cell-mediated removal of human amyloid-β

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Molecular basis for amyloid- polymorphism

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Structural Correlates of Antibodies Associated with Acute Reversal of Amyloid -related Behavioral Deficits in a Mouse Model of Alzheimer Disease

6 July 2018

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Crystallization and preliminary X-ray diffraction analysis of the Fab fragment of WO2, an antibody specific for the Abeta peptides associated with Alzheimer's disease.

6 July 2018

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Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope

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The alpha-to-beta conformational transition of Alzheimer's Abeta-(1-42) peptide in aqueous media is reversible: a step by step conformational analysis suggests the location of beta conformation seeding

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Identifiers

DOI

10.1038/SREP09649

1 reference

Dimensions Publication ID

2 August 2017

1042086198

0 references

Fatcat ID

release_4lnxrwydxzainfynp6hykk5uty

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/4lnxrwydxzainfynp6hykk5uty

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

4549621

1 reference

2 August 2017

1 reference