Adrenomedullin receptors: molecular identity and function. (Q34469406)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11754961 AND SRC:MED&resulttype=core&format=json

5 December 2019

review article

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title

Adrenomedullin receptors: molecular identity and function (English)

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5 December 2019

1

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5 December 2019

author name string

D M Smith

series ordinal

2

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5 December 2019

publication date

1 November 2001

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5 December 2019

number of pages

11

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inferred from page(s)

published in

Peptides

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5 December 2019

volume

22

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5 December 2019

issue

11

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5 December 2019

page(s)

1753-1763

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Involvement of G protein-coupled receptor kinase-6 in desensitization of CGRP receptors

5 December 2019

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Mammalian calcitonin receptor-like receptor/receptor activity modifying protein complexes define calcitonin gene-related peptide and adrenomedullin receptors in Drosophila Schneider 2 cells

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Co-expression of prepro-adrenomedullin with a putative adrenomedullin receptor gene in vascular smooth muscle

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Regulatory mechanisms that modulate signalling by G-protein-coupled receptors

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Extreme hydrops fetalis and cardiovascular abnormalities in mice lacking a functional Adrenomedullin gene

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CGRP and adrenomedullin binding correlates with transcript levels for calcitonin receptor-like receptor (CRLR) and receptor activity modifying proteins (RAMPs) in rat tissues

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[MPR14]-rADM(14-50), a novel analog of adrenomedullin, possesses potent vasodilator activity in the hindlimb vascular bed of the cat

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Cytoprotective effects of adrenomedullin in glomerular cell injury: Central role of cAMP signaling pathway

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Adrenomedullin suppresses mitogenesis in rat mesangial cells via cAMP pathway

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Rat-2 fibroblasts express specific adrenomedullin receptors, but not calcitonin-gene-related-peptide receptors, which mediate increased intracellular cAMP and inhibit mitogen-activated protein kinase activity

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A rat skeletal muscle cell line (L6) expresses specific adrenomedullin binding sites but activates adenylate cyclase via calcitonin gene-related peptide receptors

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Human calcitonin gene-related peptide activates adenylate cyclase and releases prostacyclin from human umbilical vein endothelial cells

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Pharmacological profile of BIBN4096BS, the first selective small molecule CGRP antagonist

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Desensitisation of calcitonin gene-related peptide responsiveness but not adrenomedullin responsiveness in vascular smooth muscle cells

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A potent and selective CGRP2 agonist, [Cys(Et)2,7]hCGRP alpha: comparison in prototypical CGRP1 and CGRP2 in vitro bioassays

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Specific receptors for adrenomedullin in cultured rat vascular smooth muscle cells

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7 January 2021

Adrenomedullin Binding Protein in the Plasma of Multiple Species: Characterization by Radioligand Blotting

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A novel putative G protein-coupled receptor highly expressed in lung and testis

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7 January 2021

CGRP-RCP, a novel protein required for signal transduction at calcitonin gene-related peptide and adrenomedullin receptors.

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7 January 2021

A human orphan calcitonin receptor-like structure

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7 January 2021

The N-terminus of RAMPs is a critical determinant of the glycosylation state and ligand binding of calcitonin receptor-like receptor

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7 January 2021

The amino terminus of receptor activity modifying proteins is a critical determinant of glycosylation state and ligand binding of calcitonin receptor-like receptor

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7 January 2021

Interaction of human adrenomedullin 13-52 with calcitonin gene-related peptide receptors in the microvasculature of the rat and hamster

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7 January 2021

The interaction of CGRP and adrenomedullin with a receptor expressed in the rat pulmonary vascular endothelium

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7 January 2021

Molecular Cloning of a Novel Human Receptor Gene with Homology to the Rat Adrenomedullin Receptor and High Expression in Heart and Immune System

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7 January 2021

Molecular cloning of a novel rat G-protein-coupled receptor gene expressed prominently in lung, adrenal, and liver

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7 January 2021

Adrenomedullin augments nitric oxide and tetrahydrobioptein synthesis in cytokine-stimulated vascular smooth muscle cells

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7 January 2021

Knockouts and transgenics confirm the importance of adrenomedullin in the vasculature.

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7 January 2021

Protein-protein interaction and not glycosylation determines the binding selectivity of heterodimers between the calcitonin receptor-like receptor and the receptor activity-modifying proteins

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7 January 2021

Mechanisms of adrenomedullin-induced vasodilation in the rat kidney

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7 January 2021

The selectivity and structural determinants of peptide antagonists at the CGRP receptor of rat, L6 myocytes

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7 January 2021

Mouse receptor-activity-modifying proteins 1, -2 and -3: amino acid sequence, expression and function

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7 January 2021

Adrenomedullin augments inducible nitric oxide synthase expression in cytokine-stimulated cardiac myocytes

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7 January 2021

Adrenomedullin increases inducible nitric oxide synthase in rat vascular smooth muscle cells stimulated with interleukin-1

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7 January 2021

Adrenomedullin stimulates cyclic AMP formation in rat vascular smooth muscle cells

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7 January 2021

Down-regulation of adenylate cyclase coupled to adrenomedullin receptor in vascular smooth muscle cells

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7 January 2021

Adrenomedullin: potential in physiology and pathophysiology

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7 January 2021

The molecular pharmacology of CGRP and related peptide receptor subtypes

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7 January 2021

The RAMP2/CRLR complex is a functional adrenomedullin receptor in human endothelial and vascular smooth muscle cells

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7 January 2021

Cloning and Expression of cDNA Encoding a Rat Adrenomedullin Receptor

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7 January 2021

Identification of an orphan receptor gene as a type 1 calcitonin gene-related peptide receptor

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7 January 2021

Local production and action of adrenomedullin in the rat adrenal zona glomerulosa

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7 January 2021

Receptors for adrenomedullin in human vascular endothelial cells

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7 January 2021

Expression of the Rat Adrenomedullin Receptor or a Putative Human Adrenomedullin Receptor Does Not Correlate with Adrenomedullin Binding or Functional Response

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7 January 2021

Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma

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7 January 2021

Adrenomedullin decreases both cytosolic Ca2 concentration and Ca(2 )-sensitivity in pig coronary arterial smooth muscle

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7 January 2021

Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalization and recycling

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7 January 2021

Identification of a protein that confers calcitonin gene-related peptide responsiveness to oocytes by using a cystic fibrosis transmembrane conductance regulator assay

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7 January 2021

The CGRP receptor can couple via pertussis toxin sensitive and insensitive G proteins

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7 January 2021

Expression of Adrenomedullin and Its Receptor in Normal and Malignant Human Skin: A Potential Pluripotent Role in the Integument

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7 January 2021

Distribution, functional role, and signaling mechanism of adrenomedullin receptors in the rat adrenal gland.

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7 January 2021

RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor

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7 January 2021

Adrenomedullin expression in human tumor cell lines. Its potential role as an autocrine growth factor

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7 January 2021

Rat receptor-activity-modifying proteins (RAMPs) for adrenomedullin/CGRP receptor: cloning and upregulation in obstructive nephropathy

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7 January 2021

Specific adrenomedullin binding sites and hypotension in the rat systemic vascular bed

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7 January 2021

Increased plasma concentrations of adrenomedullin correlate with relaxation of vascular tone in patients with septic shock

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7 January 2021

A new calcitonin-receptor-like sequence in rat pulmonary blood vessels

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7 January 2021

Vasodilator effect of adrenomedullin and calcitonin gene-related peptide receptors in rat mesenteric vascular beds.

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7 January 2021

Decreased gene expression of adrenomedullin receptor in mouse lungs during sepsis

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7 January 2021

Adrenomedullin inhibits transmural pressure induced mesangial cell proliferation through activation of protein kinase A

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7 January 2021

Characterisation and molecular identification of adrenomedullin binding sites in the rat spinal cord: a comparison with calcitonin gene-related peptide receptors

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7 January 2021

Desensitization and resensitization of adrenomedullin-sensitive receptor in rat mesangial cells

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7 January 2021

Adrenomedullin decreases extracellular signal-regulated kinase activity through an increase in protein phosphatase-2A activity in mesangial cells

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7 January 2021

The effect of adrenomedullin on the isolated heart

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7 January 2021

Effects of adrenomedullin and calcitonin gene-related peptide on airway and pulmonary vascular smooth muscle in guinea-pigs

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7 January 2021

Pharmacology of receptors for calcitonin gene-related peptide and amylin

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7 January 2021

Calcitonin gene-related peptide: multiple actions, multiple receptors

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7 January 2021

Molecular pharmacology of receptors for calcitonin-gene-related peptide, amylin and adrenomedullin

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7 January 2021

Structural determinants for binding to CGRP receptors expressed by human SK-N-MC and Col 29 cells: studies with chimeric and other peptides

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7 January 2021

Characterization of receptors for calcitonin gene-related peptide and adrenomedullin on the guinea-pig vas deferens

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7 January 2021

Adrenomedullin synergistically interacts with endogenous vasodilators in rats: a possible role of K(ATP) channels

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7 January 2021

Expression of calcitonin receptor-like receptor and receptor-activity-modifying proteins in human cranial arteries

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7 January 2021

Adrenomedullin stimulates two signal transduction pathways, cAMP accumulation and Ca2 mobilization, in bovine aortic endothelial cells

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7 January 2021

Mechanisms of adrenomedullin-induced increase of pulmonary blood flow in fetal sheep

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7 January 2021

Hypotension and resistance to lipopolysaccharide-induced shock in transgenic mice overexpressing adrenomedullin in their vasculature

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7 January 2021

An autocrine or a paracrine role of adrenomedullin in modulating cardiac fibroblast growth

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7 January 2021

Adrenomedullin increases intracellular Ca2 and inositol 1,4,5-trisphosphate in human oligodendroglial cell line KG-1C

1 reference

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7 January 2021

Comparative affinities of human adrenomedullin for 125I-labelled human alpha calcitonin gene related peptide ([125I]hCGRP alpha) and 125I-labelled Bolton-Hunter rat amylin ([125I]BHrAMY) specific binding sites in the rat brain

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7 January 2021

Adrenomedullin stimulates DNA synthesis and cell proliferation via elevation of cAMP in Swiss 3T3 cells

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7 January 2021

Characterisation of calcitonin gene-related peptide receptors in rat atrium and vas deferens: evidence for a [Cys(Et)(2, 7)]hCGRP-preferring receptor

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7 January 2021

Adrenomedullin dilates rat pulmonary artery rings during hypoxia: role of nitric oxide and vasodilator prostaglandins

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7 January 2021

Human adrenomedullin gene delivery protects against cardiac hypertrophy, fibrosis, and renal damage in hypertensive dahl salt-sensitive rats

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7 January 2021

Identification of adrenomedullin receptors in cultured rat astrocytes and in neuroblastboma x glioma hybrid cells (NG108-15).

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7 January 2021

Adrenomedullin and calcitonin gene-related peptide interact with the same receptor in cultured human neuroblastoma SK-N-MC cells

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7 January 2021

10.1016/S0196-9781(01)00532-0

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11754961 AND SRC:MED&resulttype=core&format=json

5 December 2019

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