The role of adenovirus E4orf4 protein in viral replication and cell killing (Q34468774)

2 August 2017

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title

The role of adenovirus E4orf4 protein in viral replication and cell killing (English)

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2 August 2017

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Branton PE

1

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2 August 2017

Roopchand DE

series ordinal

2

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2 August 2017

language of work or name

English

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publication date

1 November 2001

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2 August 2017

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2 August 2017

volume

20

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2 August 2017

issue

54

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2 August 2017

page(s)

7855-7865

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Selection of apoptosis-deficient adenovirus E4orf4 mutants in Saccharomyces cerevisiae

2 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Adenovirus early region 4 and viral DNA synthesis

21 January 2018

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21 January 2018

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The yeast proteome database (YPD) and Caenorhabditis elegans proteome database (WormPD): comprehensive resources for the organization and comparison of model organism protein information

21 January 2018

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High complexity in the expression of the B' subunit of protein phosphatase 2A0. Evidence for the existence of at least seven novel isoforms

21 January 2018

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Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

21 January 2018

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E1A signaling to p53 involves the p19(ARF) tumor suppressor

21 January 2018

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Interleukin-3-Induced Phosphorylation of BAD Through the Protein Kinase Akt

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204862

The adenovirus E4-ORF4 splicing enhancer protein interacts with a subset of phosphorylated SR proteins.

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204862

The adenovirus E1A-regulated transcription factor E4F is generated from the human homolog of nuclear factor phiAP3

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Protein phosphatase 2A1 is the major enzyme in vertebrate cell extracts that dephosphorylates several physiological substrates for cyclin-dependent protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Characterization of the major mRNAs from adenovirus 2 early region 4 by cDNA cloning and sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

21 January 2018

Integrins and anoikis

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https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Simian virus 40 small t antigen cooperates with mitogen-activated kinases to stimulate AP-1 activity

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Integrin signaling: specificity and control of cell survival and cell cycle progression

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204862

BCL-2 family members and the mitochondria in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

CDC55, a Saccharomyces cerevisiae gene involved in cellular morphogenesis: identification, characterization, and homology to the B subunit of mammalian type 2A protein phosphatase

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Akt signaling: linking membrane events to life and death decisions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

alpha- and beta-forms of the 65-kDa subunit of protein phosphatase 2A have a similar 39 amino acid repeating structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Nucleotide sequence of adenovirus 2 DNA fragment encoding for the carboxylic region of the fiber protein and the entire E4 region

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Inhibition by SR proteins of splicing of a regulated adenovirus pre-mRNA.

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Regulation of adenovirus alternative RNA splicing by dephosphorylation of SR proteins

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Structure and transcriptional regulation of protein phosphatase 2A catalytic subunit genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Induction of apoptosis by adenovirus E4orf4 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Separation of PP2A core enzyme and holoenzyme with monoclonal antibodies against the regulatory A subunit: abundant expression of both forms in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Adenovirus E4 open reading frame 4-induced apoptosis involves dysregulation of Src family kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

E4orf4, a Novel Adenovirus Death Factor That Induces p53-independent Apoptosis by a Pathway That Is Not Inhibited by zVAD-fmk

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Caspase activation by adenovirus e4orf4 protein is cell line specific and Is mediated by the death receptor pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Adenovirus E4 open reading frame 4-induced dephosphorylation inhibits E1A activation of the E2 promoter and E2F-1-mediated transactivation independently of the retinoblastoma tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Induction of p53-independent apoptosis by the adenovirus E4orf4 protein requires binding to the Balpha subunit of protein phosphatase 2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Assignment of human protein phosphatase 2A regulatory subunit genes b56alpha, b56beta, b56gamma, b56delta, and b56epsilon (PPP2R5A-PPP2R5E), highly expressed in muscle and brain, to chromosome regions 1q41, 11q12, 3p21, 6p21.1, and 7p11.2 --> p12

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Identification of a new family of protein phosphatase 2A regulatory subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Extranuclear apoptosis. The role of the cytoplasm in the execution phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

WD40 repeat proteins striatin and S/G(2) nuclear autoantigen are members of a novel family of calmodulin-binding proteins that associate with protein phosphatase 2A

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Induction of transcription factor AP-1 by adenovirus E1A protein and cAMP.

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Apoptosis by death factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Protein phosphatase 2A in Saccharomyces cerevisiae: effects on cell growth and bud morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

21 January 2018

Viruses and Apoptosis

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Caspase activation: the induced-proximity model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Dephosphorylation of simian virus 40 large-T antigen and p53 protein by protein phosphatase 2A: inhibition by small-t antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Induction of apoptosis by adenovirus E4orf4 protein is specific to transformed cells and requires an interaction with protein phosphatase 2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Adenovirus E4orf4 protein interacts with both Balpha and B' subunits of protein phosphatase 2A, but E4orf4-induced apoptosis is mediated only by the interaction with Balpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Molecular genetic analysis of Rts1p, a B' regulatory subunit of Saccharomyces cerevisiae protein phosphatase 2A

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the map kinase pathway and induces cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

A novel pool of protein phosphatase 2A is associated with microtubules and is regulated during the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Molecular cloning of a 74-kDa regulatory subunit (B" or delta) of human protein phosphatase 2A

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Identification of a novel protein phosphatase 2A regulatory subunit highly expressed in muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Vimentin dephosphorylation by protein phosphatase 2A is modulated by the targeting subunit B55.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Functional interaction between a novel protein phosphatase 2A regulatory subunit, PR59, and the retinoblastoma-related p107 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Association of protein phosphatase 2A with polyoma virus medium tumor antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Alterations of the PPP2R1B gene in human lung and colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Cdc55p, the B-type regulatory subunit of protein phosphatase 2A, has multiple functions in mitosis and is required for the kinetochore/spindle checkpoint in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Carboxymethylation of the PP2A catalytic subunit in Saccharomyces cerevisiae is required for efficient interaction with the B-type subunits Cdc55p and Rts1p

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Carboxyl methylation of the phosphoprotein phosphatase 2A catalytic subunit promotes its functional association with regulatory subunits in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

PR48, a novel regulatory subunit of protein phosphatase 2A, interacts with Cdc6 and modulates DNA replication in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Loss of a protein phosphatase 2A regulatory subunit (Cdc55p) elicits improper regulation of Swe1p degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Control of protein phosphatase 2A by simian virus 40 small-t antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Structure-function comparisons of the proapoptotic protein Bax in yeast and mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Saccharomyces cerevisiae homologs of mammalian B and B' subunits of protein phosphatase 2A direct the enzyme to distinct cellular functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Diversity in the regulatory B-subunits of protein phosphatase 2A: identification of a novel isoform highly expressed in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Specificity of the polycation-stimulated (type-2A) and ATP, Mg-dependent (type-1) protein phosphatases toward substrates phosphorylated by P34cdc2 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

Low frequency of alterations of the alpha (PPP2R1A) and beta (PPP2R1B) isoforms of the subunit A of the serine-threonine phosphatase 2A in human neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

7 January 2021

Reduced expression of the Aalpha subunit of protein phosphatase 2A in human gliomas in the absence of mutations in the Aalpha and Abeta subunit genes

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

7 January 2021

cAMP acts in synergy with E1A protein to activate transcription of the adenovirus early genes E4 and E1A

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

7 January 2021

Mutation of the C-terminal leucine residue of PP2Ac inhibits PR55/B subunit binding and confers supersensitivity to microtubule destabilization in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

7 January 2021

Adenovirus early region 4 encodes functions required for efficient DNA replication, late gene expression, and host cell shutoff

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

7 January 2021

Update: PtdIns(3,4,5)P 3 Gets Its Message Across

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

7 January 2021

Adenovirus type 5 early region 4 is responsible for E1A-induced p53-independent apoptosis

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

7 January 2021

Adenovirus E4orf4 protein reduces phosphorylation of c-Fos and E1A proteins while simultaneously reducing the level of AP-1

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

7 January 2021

The third subunit of protein phosphatase 2A (PP2A), a 55-kilodalton protein which is apparently substituted for by T antigens in complexes with the 36- and 63-kilodalton PP2A subunits, bears little resemblance to T antigens

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

7 January 2021

Adenovirus Type 5 E4 Open Reading Frame 4 Protein Induces Apoptosis in Transformed Cells

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

7 January 2021

Regulation of apoptosis by viral gene products

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https://api.crossref.org/works/10.1038/SJ.ONC.1204862

7 January 2021

mRNAs from human adenovirus 2 early region 4.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

7 January 2021

The variable subunit associated with protein phosphatase 2A0 defines a novel multimember family of regulatory subunits

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204862

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204862

1 reference

Dimensions Publication ID

2 August 2017

1053126636

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