Adenovirus early E4 genes in viral oncogenesis (Q34468767)

2 August 2017

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title

Adenovirus early E4 genes in viral oncogenesis (English)

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2 August 2017

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Täuber B

1

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2 August 2017

Dobner T

series ordinal

2

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2 August 2017

language of work or name

English

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publication date

1 November 2001

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2 August 2017

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2 August 2017

volume

20

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2 August 2017

issue

54

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2 August 2017

page(s)

7847-7854

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Adenovirus type 9-induced tumorigenesis in the rat mammary gland related to sex hormonal state

2 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Induction of mammary fibroadenomas in rats by adenovirus type 9

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Genetic analysis of a potential zinc-binding domain of the adenovirus E4 34k protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Adenovirus E4 34k and E4 11k inhibit double strand break repair and are physically associated with the cellular DNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Interaction of adenoviral E4 and E1b products in late gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Targeting of adenovirus E1A and E4-ORF3 proteins to nuclear matrix-associated PML bodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

A functional complex of adenovirus proteins E1B-55kDa and E4orf6 is necessary to modulate the expression level of p53 but not its transcriptional activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

A role for a bent DNA structure in E2F-mediated transcription activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Expression of adenovirus type 5 E4 Orf2 protein during lytic infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Nuclear export of the E1B 55-kDa and E4 34-kDa adenoviral oncoproteins mediated by a rev-like signal sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Blockage by adenovirus E4orf6 of transcriptional activation by the p53 tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Adenovirus replication is coupled with the dynamic properties of the PML nuclear structure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

PDZ domains: fundamental building blocks in the organization of protein complexes at the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Comparison of viral RNA sequences in adenovirus 2-transformed and lytically infected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Viral nucleic acid sequences in transformed cells. IV. A study of the sequences of adenovirus 5 DNA and RNA in four lines of adenovirus 5-transformed rodent cells using specific fragments of the viral genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Adenovirus transcription. V. Quantitation of viral RNA sequences in adenovirus 2-infected and transformed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Characterization of the major mRNAs from adenovirus 2 early region 4 by cDNA cloning and sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Oncogenic human papillomavirus E6 proteins target the discs large tumour suppressor for proteasome-mediated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Interactions of the PDZ-protein MAGI-1 with adenovirus E4-ORF1 and high-risk papillomavirus E6 oncoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Enhanced expression of p53 in human cells infected with mutant adenoviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

E2F from adenovirus-infected cells binds cooperatively to DNA containing two properly oriented and spaced recognition sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Nucleotide sequence of adenovirus 2 DNA fragment encoding for the carboxylic region of the fiber protein and the entire E4 region

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

The adenovirus early region 4 open reading frame 6/7 protein regulates the DNA binding activity of the cellular transcription factor, E2F, through a direct complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Requirement for the adenovirus type 9 E4 region in production of mammary tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Mammary tumors induced by human adenovirus type 9: a role for the viral early region 4 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Oncogenic capacity of the E2F1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Induction of apoptosis by adenovirus E4orf4 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

E1A transcription induction: enhanced binding of a factor to upstream promoter sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Identification of a cellular transcription factor involved in E1A trans-activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Role of an adenovirus E2 promoter binding factor in E1A-mediated coordinate gene control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Multi-PDZ domain protein MUPP1 is a cellular target for both adenovirus E4-ORF1 and high-risk papillomavirus type 18 E6 oncoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Binding of human virus oncoproteins to hDlg/SAP97, a mammalian homolog of the Drosophila discs large tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

The adenovirus type 5 E1b 55K and E4 Orf3 proteins associate in infected cells and affect ND10 components

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Oncogenic potential of the adenovirus E4orf6 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

An adenovirus E4 gene product trans-activates E2 transcription and stimulates stable E2F binding through a direct association with E2F.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

The adenovirus E4orf6 protein can promote E1A/E1B-induced focus formation by interfering with p53 tumor suppressor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Two distinct activities contribute to the oncogenic potential of the adenovirus type 5 E4orf6 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

The adenovirus E4orf6 protein contributes to malignant transformation by antagonizing E1A-induced accumulation of the tumor suppressor protein p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

"Hit-and-run" transformation by adenovirus oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Creation and repair of specific DNA double-strand breaks in vivo following infection with adenovirus vectors expressing Saccharomyces cerevisiae HO endonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

The C-terminal 70 amino acids of the adenovirus E4-ORF6/7 protein are essential and sufficient for E2F complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

The E4-6/7 protein functionally compensates for the loss of E1A expression in adenovirus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

The adenovirus E4-6/7 protein transactivates the E2 promoter by inducing dimerization of a heteromeric E2F complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Identification of three functions of the adenovirus e4orf6 protein that mediate p53 degradation by the E4orf6-E1B55K complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Identification and characterization of an immunologically conserved adenovirus early region 11,000 Mr protein and its association with the nuclear matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Induction of the cellular E2F-1 promoter by the adenovirus E4-6/7 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

The DNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Several E4 region functions influence mammary tumorigenesis by human adenovirus type 9

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

The quest for human cancer viruses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Deletion of the E4 region of the genome produces adenovirus DNA concatemers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Viral and cellular factors that target the promyelocytic leukemia oncogenic domains strongly activate a glucocorticoid-responsive promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

E1B 55-kilodalton oncoproteins of adenovirus types 5 and 12 inactivate and relocalize p53, but not p51 or p73, and cooperate with E4orf6 proteins to destabilize p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Multiple members of the E2F transcription factor family are the products of oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Proto-oncogene PML controls genes devoted to MHC class I antigen presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

A role for PML and the nuclear body in genomic stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

Use of the E2F transcription factor by DNA tumor virus regulatory proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

7 January 2021

Nuclear export of adenovirus RNA.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

7 January 2021

Viral gene products in adenovirus type-2 transformed hamster cells

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

7 January 2021

Expression of early viral gene products in adenovirus type 12-infected and -transformed cells

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

7 January 2021

E2F-1 functions in mice to promote apoptosis and suppress proliferation

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

7 January 2021

Adenovirus early region 4 34-kilodalton protein directs the nuclear localization of the early region 1B 55-kilodalton protein in primate cells.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

7 January 2021

Overexpression of cyclin A inhibits augmentation of recombinant adeno-associated virus transduction by the adenovirus E4orf6 protein

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

7 January 2021

Adenovirus early region 4 encodes functions required for efficient DNA replication, late gene expression, and host cell shutoff

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

7 January 2021

An adenovirus early region 4 gene product is required for induction of the infection-specific form of cellular E2F activity

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

7 January 2021

Adenovirus type 9 E4 open reading frame 1 encodes a transforming protein required for the production of mammary tumors in rats

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

7 January 2021

Human adenovirus type 9-induced rat mammary tumors

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

7 January 2021

Adenovirus type 5 E4orf3 protein relieves p53 inhibition by E1B-55-kilodalton protein.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

7 January 2021

Genetic analysis of the adenovirus E4 6/7 trans activator: interaction with E2F and induction of a stable DNA-protein complex are critical for activity

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

7 January 2021

An arginine-faced amphipathic alpha helix is required for adenovirus type 5 e4orf6 protein function

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

7 January 2021

Localization of the adenovirus early region 1B 55-kilodalton protein during lytic infection: association with nuclear viral inclusions requires the early region 4 34-kilodalton protein

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

7 January 2021

Adenovirus infection induces rearrangements in the intranuclear distribution of the nuclear body-associated PML protein.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

7 January 2021

DNA-binding activity of the adenovirus-induced E4F transcription factor is regulated by phosphorylation

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

7 January 2021

Adenovirus early region 1B 58,000-dalton tumor antigen is physically associated with an early region 4 25,000-dalton protein in productively infected cells

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

7 January 2021

The large E1B protein together with the E4orf6 protein target p53 for active degradation in adenovirus infected cells

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

7 January 2021

Early region 1 transforming functions are dispensable for mammary tumorigenesis by human adenovirus type 9.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

7 January 2021

mRNAs from human adenovirus 2 early region 4.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

7 January 2021

A carboxy-terminal region required by the adenovirus type 9 E4 ORF1 oncoprotein for transformation mediates direct binding to cellular polypeptides

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

7 January 2021

Human adenovirus early region 4 open reading frame 1 genes encode growth-transforming proteins that may be distantly related to dUTP pyrophosphatase enzymes

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

7 January 2021

Induction of transformation and p53-dependent apoptosis by adenovirus type 5 E4orf6/7 cDNA.

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204914

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204914

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Dimensions Publication ID

2 August 2017

1035650915

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