The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias (Q34465221)

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1 March 2020

title

The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias (English)

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Anna K Hagström-Andersson

1

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Xiang Chen

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Linda Holmfeldt

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Robert Huether

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Gang Wu

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Stanley Pounds

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Elaine R Mardis

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Matthew Parker

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Deqing Pei

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St. Jude Children's Research Hospital–Washington University Pediatric Cancer Genome Project

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St. Jude Children's Research Hospital–Washington University Pediatric Cancer Genome Project

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Michael Rusch

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language of work or name

English

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publication date

2 March 2015

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1 March 2020

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volume

47

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issue

4

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page(s)

330-337

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Targeting bromodomains: epigenetic readers of lysine acetylation

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Chromatin structural elements and chromosomal translocations in leukemia

6 July 2018

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6 July 2018

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Clinical resistance to the kinase inhibitor PKC412 in acute myeloid leukemia by mutation of Asn-676 in the FLT3 tyrosine kinase domain

6 July 2018

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6 July 2018

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Activating mutations of the noonan syndrome-associated SHP2/PTPN11 gene in human solid tumors and adult acute myelogenous leukemia

6 July 2018

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Prediction and Functional Analysis of Native Disorder in Proteins from the Three Kingdoms of Life

6 July 2018

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The structural basis for autoinhibition of FLT3 by the juxtamembrane domain

6 July 2018

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Biological and therapeutic aspects of infant leukemia

6 July 2018

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Primer3 on the WWW for general users and for biologist programmers

6 July 2018

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Fine structure of translocation breakpoints in leukemic blasts with chromosomal translocation t(4;11): the DNA damage-repair model of translocation

6 July 2018

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Backtracking leukemia to birth: Identification of clonotypic gene fusion sequences in neonatal blood spots

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Identification of complex genomic breakpoint junctions in the t(9;11) MLL-AF9 fusion gene in acute leukemia

6 July 2018

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The der(11)-encoded MLL/AF-4 fusion transcript is consistently detected in t(4;11)(q21;q23)-containing acute lymphoblastic leukemia.

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Cytogenetic features of infants less than 12 months of age at diagnosis of acute lymphoblastic leukemia: impact of the 11q23 breakpoint on outcome: a report of the Childrens Cancer Group

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4553269

A treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia (Interfant-99): an observational study and a multicentre randomised trial.

6 July 2018

1 reference

In utero rearrangements in the trithorax-related oncogene in infant leukaemias.

21 January 2018

1 reference

Implementation of array based whole-genome high-resolution technologies confirms the absence of secondary copy-number alterations in MLL-AF4-positive infant ALL patients

21 January 2018

1 reference

A DNA damage repair mechanism is involved in the origin of chromosomal translocations t(4;11) in primary leukemic cells

21 January 2018

1 reference

Mutations in PTPN11 implicate the SHP-2 phosphatase in leukemogenesis

21 January 2018

1 reference

Exome sequencing identifies recurring FLT3 N676K mutations in core-binding factor leukemia.

21 January 2018

1 reference

The silent mutational landscape of infant MLL-AF4 pro-B acute lymphoblastic leukemia.

21 January 2018

1 reference

K-Ras mutations and N-Ras mutations in childhood acute leukemias with or without mixed-lineage leukemia gene rearrangements.

21 January 2018

1 reference

Secondary mutations in t(4;11) leukemia patients

21 January 2018

1 reference

Mixed-lineage-leukemia (MLL) fusion protein collaborates with Ras to induce acute leukemia through aberrant Hox expression and Raf activation

21 January 2018

1 reference

The Protein Data Bank: a historical perspective.

21 January 2018

1 reference

Clonal variegation and dynamic competition of leukemia-initiating cells in infant acute lymphoblastic leukemia with MLL rearrangement

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25730765

12 December 2020

inferred from PubMed ID database lookup

Abnormalities of chromosome bands 15q13-15 in childhood acute lymphoblastic leukemia

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25730765

12 December 2020

inferred from PubMed ID database lookup

Activated K-Ras protein accelerates human MLL/AF4-induced leukemo-lymphomogenicity in a transgenic mouse model

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25730765

12 December 2020

inferred from PubMed ID database lookup

Genome sequencing of 161 Mycobacterium tuberculosis isolates from China identifies genes and intergenic regions associated with drug resistance

1 reference

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NG.3230

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25730765 AND SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25730765 AND SRC:MED&resulttype=core&format=json

1 March 2020

PubMed publication ID

25730765

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25730765 AND SRC:MED&resulttype=core&format=json