Fyn inhibition rescues established memory and synapse loss in Alzheimer mice (Q34464152)

2 August 2017

title

Fyn inhibition rescues established memory and synapse loss in Alzheimer mice (English)

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2 August 2017

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protein tyrosine kinase 2 beta

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Major prion protein

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FYN proto-oncogene, Src family tyrosine kinase

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Amyloid beta precursor protein

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regulation of synaptic plasticity

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Sophie A Robinson

7

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Mikhail A Kostylev

object named as

Mikhail A Kostylev

5

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Stephen M. Strittmatter

object named as

Stephen M Strittmatter

11

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author name string

Adam C Kaufman

1

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2 August 2017

Santiago V Salazar

2

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2 August 2017

Laura T Haas

3

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2 August 2017

Jinhee Yang

4

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2 August 2017

Amanda T Jeng

6

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2 August 2017

Erik C Gunther

8

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2 August 2017

Christopher H van Dyck

9

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2 August 2017

Haakon B Nygaard

10

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2 August 2017

publication date

21 March 2015

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2 August 2017

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2 August 2017

volume

77

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2 August 2017

issue

6

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2 August 2017

page(s)

953-971

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describes a project that uses

2 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4447598/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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CAKbeta/Pyk2 kinase is a signaling link for induction of long-term potentiation in CA1 hippocampus

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice

6 July 2018

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Altered synaptic dynamics during normal brain aging.

6 July 2018

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A phase II trial of the Src kinase inhibitor saracatinib (AZD0530) in patients with metastatic or locally advanced gastric or gastro esophageal junction (GEJ) adenocarcinoma: a trial of the PMH phase II consortium

27 October 2018

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CD36 signals to the actin cytoskeleton and regulates microglial migration via a p130Cas complex.

27 October 2018

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Fyn kinase induces synaptic and cognitive impairments in a transgenic mouse model of Alzheimer's disease.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447598

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447598

Fyn kinase modulates synaptotoxicity, but not aberrant sprouting, in human amyloid precursor protein transgenic mice.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447598

A CD36-initiated signaling cascade mediates inflammatory effects of beta-amyloid.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447598

Expression of a novel form of the fyn proto-oncogene in hematopoietic cells

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25707991

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A phase I/II study of the Src inhibitor saracatinib (AZD0530) in combination with gemcitabine in advanced pancreatic cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25707991

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/ANA.24394

1 reference

2 August 2017

1 reference

2 August 2017

1 reference