NMDA receptor antagonists as analgesics: focus on the NR2B subtype (Q34455114)

2 August 2017

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title

NMDA receptor antagonists as analgesics: focus on the NR2B subtype (English)

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2 August 2017

Chizh BA

1

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2 August 2017

Headley PM

series ordinal

2

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2 August 2017

Tzschentke TM

series ordinal

3

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2 August 2017

publication date

1 December 2001

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Trends in Pharmacological Sciences

2 August 2017

published in

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2 August 2017

volume

22

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2 August 2017

issue

12

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2 August 2017

page(s)

636-642

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Developmental and regional expression in the rat brain and functional properties of four NMDA receptors

2 August 2017

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Selective NMDA NR2B antagonists induce antinociception without motor dysfunction: correlation with restricted localisation of NR2B subunit in dorsal horn.

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A novel mechanism of activity-dependent NMDA receptor antagonism describes the effect of ifenprodil in rat cultured cortical neurones

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Pharmacological characterization of interactions of RO 25-6981 with the NR2B (epsilon2) subunit

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Phenylethanolamines inhibit NMDA receptors by enhancing proton inhibition

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(1S,2S)-1-(4-Hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidino)-1-propanol: A Potent New Neuroprotectant Which Blocks N-Methyl-D-Aspartate Responses

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Localization of N-methyl-D-aspartate NR2B subunits on primary sensory neurons that give rise to small-caliber sciatic nerve fibers in rats

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Distinct synaptic and extrasynaptic NMDA receptors identified in dorsal horn neurones of the adult rat spinal cord

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Supraspinal vs spinal sites of the antinociceptive action of the subtype-selective NMDA antagonist ifenprodil

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Potent analgesia induced in rats by combined action at PCP and polyamine recognition sites of the NMDA receptor complex.

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Involvement of Spinal NMDA Receptors in Capsaicin-Induced Nociception

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Genetic enhancement of inflammatory pain by forebrain NR2B overexpression

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Molecular evidence for the involvement of NR2B subunit containing N-methyl-D-aspartate receptors in the development of morphine-induced place preference

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Peripheral excitatory amino acids

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Enhancement of NMDA-induced current by the putative NR2B selective antagonist ifenprodil

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Blockade of the polyamine site of NMDA receptors produces antinociception and enhances the effect of morphine, in mice

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Modulation of [3H]MK-801 binding to NMDA receptors in vivo and in vitro

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Antinociceptive activity of CP‐101,606, an NMDA receptor NR2B subunit antagonist

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7 January 2021

Systemic ketamine attenuates nociceptive behaviors in a rat model of peripheral neuropathy

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7 January 2021

The clinically tested N-methyl-D-aspartate receptor antagonist memantine blocks and reverses thermal hyperalgesia in a rat model of painful mononeuropathy

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7 January 2021

Effects of a partial agonist and a full antagonist acting at the glycine site of the NMDA receptor on inflammation-induced mechanical hyperalgesia in rats

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Different capability of N-methyl-D-aspartate antagonists to elicit EEG and behavioural phencyclidine-like effects in rats

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7 January 2021

Evaluation of the reinforcing effects of eliprodil in rhesus monkeys and its discriminative stimulus effects in rats

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Effects of the non-competitive NMDA receptor antagonist ifenprodil on the morphine-induced place preference in mice.

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A novel NMDA antagonist, MK-801, impairs performance in a hippocampal-dependent spatial learning task.

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7 January 2021

Effects of NMDA receptor antagonists and sigma ligands on the acquisition of conditioned fear in mice

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7 January 2021

Psychotogenicity and N-methyl-D-aspartate receptor antagonism: implications for neuroprotective pharmacotherapy.

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7 January 2021

Comparison of ketamine and pethidine in experimental and postoperative pain

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7 January 2021

Pharmacological effects of the non-competitive NMDA antagonist CNS 1102 in normal volunteers

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7 January 2021

[Quality of life of patient with peripheral arterial obliterative disease treated with ifenprodil tartrate. Results of an ARTEMIS study]

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7 January 2021

Lack of amnestic, psychotomimetic or impairing effect on psychomotor performance of eliprodil, a new NMDA antagonist.

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A double-blind, placebo-controlled study of the safety, tolerability and pharmacokinetics of CP-101,606 in patients with a mild or moderate traumatic brain injury

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7 January 2021

10.1016/S0165-6147(00)01863-0

Identifiers

DOI

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2 August 2017

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