pRB induces Sp1 activity by relieving inhibition mediated by MDM2. (Q34446511)

2 August 2017

title

pRB induces Sp1 activity by relieving inhibition mediated by MDM2. (English)

1 reference

2 August 2017

T Johnson-Pais

1

1 reference

2 August 2017

C Degnin

series ordinal

2

1 reference

2 August 2017

M J Thayer

series ordinal

3

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2 August 2017

language of work or name

English

0 references

publication date

1 February 2001

1 reference

Proceedings of the National Academy of Sciences of the United States of America

2 August 2017

published in

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2 August 2017

volume

98

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2 August 2017

issue

5

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2 August 2017

page(s)

2211-2216

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A tale of three fingers: the family of mammalian Sp/XKLF transcription factors

2 August 2017

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6 July 2018

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Myogenic basic helix-loop-helix proteins and Sp1 interact as components of a multiprotein transcriptional complex required for activity of the human cardiac alpha-actin promoter

6 July 2018

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6 July 2018

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6 July 2018

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A unique cathepsin-like protease isolated from CV-1 cells is involved in rapid degradation of retinoblastoma susceptibility gene product, RB, and transcription factor SP1.

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Amplification of MDM2 inhibits MyoD-mediated myogenesis

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6 July 2018

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6 July 2018

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Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

6 July 2018

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Sp-1 binds promoter elements regulated by the RB protein and Sp-1-mediated transcription is stimulated by RB coexpression

6 July 2018

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6 July 2018

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Physical and functional interaction between wild-type p53 and mdm2 proteins

6 July 2018

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Negative regulation of Sp1 trans-activation is correlated with the binding of cellular proteins to the amino terminus of the Sp1 trans-activation domain

6 July 2018

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The retinoblastoma gene product RB stimulates Sp1-mediated transcription by liberating Sp1 from a negative regulator

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Mapping of the p53 and mdm-2 Interaction Domains

6 July 2018

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The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter

6 July 2018

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Two distinct transcription factors bind to the HSV thymidine kinase promoter in vitro

6 July 2018

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Muscle-specific expression of the cardiac alpha-actin gene requires MyoD1, CArG-box binding factor, and Sp1.

6 July 2018

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Different activation domains of Sp1 govern formation of multimers and mediate transcriptional synergism

6 July 2018

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Amplification of a gene encoding a p53-associated protein in human sarcomas

6 July 2018

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The retinoblastoma gene product regulates Sp1-mediated transcription

6 July 2018

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The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

6 July 2018

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Signaling to p53: breaking the MDM2-p53 circuit

6 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073/PNAS.051415898

RB regulates the stability and the apoptotic function of p53 via MDM2

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073/PNAS.051415898

21 January 2018

Identifiers

DOI

10.1073/PNAS.051415898

1 reference

2 August 2017

0 references

1 reference

2 August 2017

1 reference