Cell metabolism: an essential link between cell growth and apoptosis (Q34440592)

2 August 2017

title

Cell metabolism: an essential link between cell growth and apoptosis (English)

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extrinsic apoptotic signaling pathway in absence of ligand

2 August 2017

main subject

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Gene Ontology release 2020-05-02

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1 reference

Emily F Mason

1

1 reference

2 August 2017

Jeffrey C Rathmell

series ordinal

2

1 reference

2 August 2017

language of work or name

English

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publication date

8 September 2010

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2 August 2017

number of pages

10

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Biochimica et Biophysica Acta

inferred from page(s)

published in

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2 August 2017

volume

1813

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2 August 2017

issue

4

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2 August 2017

page(s)

645-654

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Small-molecule inhibitors of c-Myc transcriptional factor suppress proliferation and induce apoptosis of promyelocytic leukemia cell via cell cycle arrest

2 August 2017

cites work

1 reference

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6 July 2018

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Novel mutations and their functional and clinical relevance in myeloproliferative neoplasms: JAK2, MPL, TET2, ASXL1, CBL, IDH and IKZF1

6 July 2018

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AMP kinase-mediated activation of the BH3-only protein Bim couples energy depletion to stress-induced apoptosis

6 July 2018

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Imatinib resistance associated with BCR-ABL upregulation is dependent on HIF-1alpha-induced metabolic reprograming

6 July 2018

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Perturbation of the Bcl-2 network and an induced Noxa/Bcl-xL interaction trigger mitochondrial dysfunction after DNA damage

6 July 2018

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AMP-activated protein kinase antagonizes pro-apoptotic extracellular signal-regulated kinase activation by inducing dual-specificity protein phosphatases in response to glucose deprivation in HCT116 carcinoma

6 July 2018

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Targeting cancer cell metabolism: the combination of metformin and 2-deoxyglucose induces p53-dependent apoptosis in prostate cancer cells

6 July 2018

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The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

6 July 2018

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Hypoxia-inducible factor-1-dependent mechanisms of vascularization and vascular remodelling

6 July 2018

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6 July 2018

The BCL-2 family reunion

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Inhibition of glycolysis enhances cisplatin-induced apoptosis in ovarian cancer cells

6 July 2018

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PPARs: diverse regulators in energy metabolism and metabolic diseases

6 July 2018

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Rethinking the Warburg effect with Myc micromanaging glutamine metabolism

6 July 2018

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mTOR regulation of autophagy

6 July 2018

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Akt and c-Myc differentially activate cellular metabolic programs and prime cells to bioenergetic inhibition

6 July 2018

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Mutant metabolic enzymes are at the origin of gliomas

6 July 2018

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The glucose-responsive transcription factor ChREBP contributes to glucose-dependent anabolic synthesis and cell proliferation

6 July 2018

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Myeloid progenitor cells lacking p53 exhibit delayed up-regulation of Puma and prolonged survival after cytokine deprivation.

6 July 2018

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Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

6 July 2018

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Protein kinase C: poised to signal

6 July 2018

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bcl-2/Adenovirus E1B 19-kd interacting protein 3 (BNIP3) regulates hypoxia-induced neural precursor cell death

6 July 2018

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18F-FDG small-animal PET/CT differentiates trastuzumab-responsive from unresponsive human breast cancer xenografts in athymic mice

6 July 2018

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Recurring mutations found by sequencing an acute myeloid leukemia genome

6 July 2018

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BH3-only proteins and their roles in programmed cell death

6 July 2018

1 reference

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Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha

6 July 2018

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Time-dependent effects of imatinib in human leukaemia cells: a kinetic NMR-profiling study

6 July 2018

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IDH1 and IDH2 mutations in gliomas

6 July 2018

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c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

6 July 2018

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6 July 2018

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Prolyl hydroxylase inhibitors depend on extracellular glucose and hypoxia-inducible factor (HIF)-2alpha to inhibit cell death caused by nerve growth factor (NGF) deprivation: evidence that HIF-2alpha has a role in NGF-promoted survival of sympatheti

6 July 2018

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Take your PIK: phosphatidylinositol 3-kinase inhibitors race through the clinic and toward cancer therapy

6 July 2018

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Knockout of myeloid cell leukemia-1 induces liver damage and increases apoptosis susceptibility of murine hepatocytes.

6 July 2018

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Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

6 July 2018

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Glucose metabolism attenuates p53 and Puma-dependent cell death upon growth factor deprivation

6 July 2018

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Transcriptional control of energy homeostasis by the estrogen-related receptors

6 July 2018

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AMPK phosphorylation of raptor mediates a metabolic checkpoint

6 July 2018

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Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy.

6 July 2018

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The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

6 July 2018

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Pyruvate kinase M2 is a phosphotyrosine-binding protein

6 July 2018

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How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?

6 July 2018

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Dual role of proapoptotic BAD in insulin secretion and beta cell survival

6 July 2018

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Small-molecule inhibition of 6-phosphofructo-2-kinase activity suppresses glycolytic flux and tumor growth.

6 July 2018

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The biology of cancer: metabolic reprogramming fuels cell growth and proliferation

6 July 2018

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The BCL-2 protein family: opposing activities that mediate cell death

6 July 2018

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The BH3-only protein Puma plays an essential role in cytokine deprivation induced apoptosis of mast cells

6 July 2018

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ER stress triggers apoptosis by activating BH3-only protein Bim

6 July 2018

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Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1.

6 July 2018

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Cytokine stimulation promotes glucose uptake via phosphatidylinositol-3 kinase/Akt regulation of Glut1 activity and trafficking

6 July 2018

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6 July 2018

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Mitochondrial membrane permeabilization in cell death

6 July 2018

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A mitochondria-K channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth

6 July 2018

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Rapid turnover of mcl-1 couples translation to cell survival and apoptosis

6 July 2018

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Loss of Mcl-1 protein and inhibition of electron transport chain together induce anoxic cell death

6 July 2018

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N-glycan processing in ER quality control

6 July 2018

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The antiapoptotic protein Mcl-1 is essential for the survival of neutrophils but not macrophages

6 July 2018

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A small-molecule c-Myc inhibitor, 10058-F4, induces cell-cycle arrest, apoptosis, and myeloid differentiation of human acute myeloid leukemia

6 July 2018

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Phosphatidylinositol 3-kinase-dependent modulation of carnitine palmitoyltransferase 1A expression regulates lipid metabolism during hematopoietic cell growth

6 July 2018

1 reference

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Bim and Bad mediate imatinib-induced killing of Bcr/Abl leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic.

6 July 2018

1 reference

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Mediators of endoplasmic reticulum stress-induced apoptosis

6 July 2018

1 reference

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Mitochondrial hexokinases, novel mediators of the antiapoptotic effects of growth factors and Akt.

6 July 2018

1 reference

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TIGAR, a p53-inducible regulator of glycolysis and apoptosis

6 July 2018

1 reference

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FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal

6 July 2018

1 reference

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The Noxa/Mcl-1 axis regulates susceptibility to apoptosis under glucose limitation in dividing T cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

p53 regulates mitochondrial respiration

6 July 2018

1 reference

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Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy

6 July 2018

1 reference

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Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

KGF induces lipogenic genes through a PI3K and JNK/SREBP-1 pathway in H292 cells

6 July 2018

1 reference

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Exposure to chronic high glucose induces beta-cell apoptosis through decreased interaction of glucokinase with mitochondria: downregulation of glucokinase in pancreatic beta-cells

6 July 2018

1 reference

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Contraction signaling to glucose transport in skeletal muscle

6 July 2018

1 reference

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ATP citrate lyase is an important component of cell growth and transformation

6 July 2018

1 reference

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Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis

6 July 2018

1 reference

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Pyruvate kinase type M2 and its role in tumor growth and spreading

6 July 2018

1 reference

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AMP-activated protein kinase induces a p53-dependent metabolic checkpoint

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

ABL oncogenes and phosphoinositide 3-kinase: mechanism of activation and downstream effectors

6 July 2018

1 reference

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Chronic myeloid leukaemia: an investigation into the role of Bcr-Abl-induced abnormalities in glucose transport regulation.

6 July 2018

1 reference

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Growth factor regulation of autophagy and cell survival in the absence of apoptosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

Glycolytic enzymes can modulate cellular life span

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

Imatinib (STI571)-mediated changes in glucose metabolism in human leukemia BCR-ABL-positive cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

Omomyc expression in skin prevents Myc-induced papillomatosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

Akt inhibits apoptosis downstream of BID cleavage via a glucose-dependent mechanism involving mitochondrial hexokinases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

Glucose transporter-1-deficient mice exhibit impaired development and deformities that are similar to diabetic embryopathy.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

Akt-Directed Glucose Metabolism Can Prevent Bax Conformation Change and Promote Growth Factor-Independent Survival

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

On the Origin of Cancer Cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

The Bcl2 family: regulators of the cellular life-or-death switch

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

6 July 2018

1 reference

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Bcl-2 family members and functional electron transport chain regulate oxygen deprivation-induced cell death

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

Tissue gradients of energy metabolites mirror oxygen tension gradients in a rat mammary carcinoma model

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

Expression of bbc3, a pro-apoptotic BH3-only gene, is regulated by diverse cell death and survival signals

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

Growth factors can influence cell growth and survival through effects on glucose metabolism

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

PUMA, a novel proapoptotic gene, is induced by p53

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

Protective role of Bcl2 in metabolic oxidative stress-induced cell death.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

Decreased glucose transporter expression triggers BAX-dependent apoptosis in the murine blastocyst

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

mcl-1 is an immediate-early gene activated by the granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling pathway and is one component of the GM-CSF viability response

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

bcl-2 inhibits death of central neural cells induced by multiple agents

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

Social controls on cell survival and cell death

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

Preferential elevation of protein kinase C isoform beta II and diacylglycerol levels in the aorta and heart of diabetic rats: differential reversibility to glycemic control by islet cell transplantation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

Glycolysis inhibition sensitizes tumor cells to death receptors-induced apoptosis by AMP kinase activation leading to Mcl-1 block in translation.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

Activation of AMP-activated protein kinase induces p53-dependent apoptotic cell death in response to energetic stress

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

Monitoring tumor glucose utilization by positron emission tomography for the prediction of treatment response to epidermal growth factor receptor kinase inhibitors

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

GLUT1 deficiency links nutrient availability and apoptosis during embryonic development

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

Anoxia is necessary for tumor cell toxicity caused by a low-oxygen environment

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

Greater cell cycle inhibition and cytotoxicity induced by 2-deoxy-d-glucose in tumor cells treated under hypoxic vs aerobic conditions

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

Upregulation of GLUT1 expression is necessary for hypertrophy and survival of neonatal rat cardiomyocytes

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

Interleukin-3-mediated cell survival signals include phosphatidylinositol 3-kinase-dependent translocation of the glucose transporter GLUT1 to the cell surface

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

Bcl-XL maintains mitochondrial function in murine astrocytes deprived of glucose

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

Decreased glycolytic metabolism contributes to but is not the inducer of apoptosis following IL-3-starvation

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

Upregulation of glucose metabolism during intimal lesion formation is coupled to the inhibition of vascular smooth muscle cell apoptosis. Role of GSK3beta

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

Tumor induction by the c-Myc target genes rcl and lactate dehydrogenase A.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

Human glucose-6-phosphate dehydrogenase (G6PD) gene transforms NIH 3T3 cells and induces tumors in nude mice

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

Overexpression of bcl-xL protects astrocytes from glucose deprivation and is associated with higher glutathione, ferritin, and iron levels.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010257

High glucose increases diacylglycerol mass and activates protein kinase C in mesangial cell cultures

27 October 2018

1 reference

12 December 2020

Inhibition of doxorubicin-induced apoptosis in vivo by 2-deoxy-D-glucose

1 reference

12 December 2020

Correlation of diacylglycerol level and protein kinase C activity in rat retina to retinal circulation

1 reference

12 December 2020

Glucose deprivation-induced cytotoxicity in drug resistant human breast carcinoma MCF-7/ADR cells: role of c-myc and bcl-2 in apoptotic cell death

1 reference

12 December 2020

Phosphorylation and Activation of Heart 6-Phosphofructo-2-kinase by Protein Kinase B and Other Protein Kinases of the Insulin Signaling Cascades

1 reference

12 December 2020

Role of hypoxia-induced Bax translocation and cytochrome c release in reoxygenation injury

1 reference

12 December 2020

Hypoxia-Inducible Factor-1 (HIF-1)

1 reference

12 December 2020

Induction of endoplasmic reticulum stress in retinal pericytes by glucose deprivation

1 reference

12 December 2020

Deregulation of glucose transporter 1 and glycolytic gene expression by c-Myc

1 reference

12 December 2020

10.1016/J.BBAMCR.2010.08.011

Identifiers

DOI

1 reference

2 August 2017

1 reference

2 August 2017

1 reference