NADPH oxidase NOX4 mediates stellate cell activation and hepatocyte cell death during liver fibrosis development. (Q34438060)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23049784 AND SRC:MED&resulttype=core&format=json

10 March 2020

title

NADPH oxidase NOX4 mediates stellate cell activation and hepatocyte cell death during liver fibrosis development (English)

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10 March 2020

1 reference

1

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10 March 2020

Eva Crosas-Molist

3

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10 March 2020

Cesáreo Roncero

4

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Conrado M Fernandez Rodríguez

10 March 2020

5

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10 March 2020

Robert Eferl

8

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10 March 2020

Wolfgang Mikulits

9

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10 March 2020

Isabel Fabregat

10

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10 March 2020

author name string

Jèssica Mainez

2

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10 March 2020

Fernando Pinedo

6

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10 March 2020

Heidemarie Huber

7

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10 March 2020

language of work or name

English

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publication date

26 September 2012

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10 March 2020

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10 March 2020

volume

7

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issue

9

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10 March 2020

page(s)

e45285

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Creative Commons Attribution 4.0 International

10 March 2020

copyright license

start time

26 September 2012

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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The nicotinamide adenine dinucleotide phosphate oxidase (NOX) homologues NOX1 and NOX2/gp91(phox) mediate hepatic fibrosis in mice

6 July 2018

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Reactive oxygen species and NADPH oxidase 4 induced by transforming growth factor β1 are the therapeutic targets of polyenylphosphatidylcholine in the suppression of human hepatic stellate cell activation

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ROS signaling by NOX4 drives fibroblast-to-myofibroblast differentiation in the diseased prostatic stroma

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α-Lipoic acid inhibits liver fibrosis through the attenuation of ROS-triggered signaling in hepatic stellate cells activated by PDGF and TGF-β.

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NADPH oxidase 4 mediates TGF-β-induced smooth muscle α-actin via p38MAPK and serum response factor

6 July 2018

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First in Class, Potent, and Orally Bioavailable NADPH Oxidase Isoform 4 (Nox4) Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis

6 July 2018

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Snail1 suppresses TGF-beta-induced apoptosis and is sufficient to trigger EMT in hepatocytes

6 July 2018

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NOX4/NADPH oxidase expression is increased in pulmonary fibroblasts from patients with idiopathic pulmonary fibrosis and mediates TGFbeta1-induced fibroblast differentiation into myofibroblasts.

6 July 2018

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Reduced nicotinamide adenine dinucleotide phosphate oxidase 2 plays a key role in stellate cell activation and liver fibrogenesis in vivo

6 July 2018

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Hepatocyte NAD(P)H oxidases as an endogenous source of reactive oxygen species during hepatitis C virus infection

6 July 2018

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Liver fibrosis: a dynamic and potentially reversible process

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Curcumin improves sclerosing cholangitis in Mdr2-/- mice by inhibition of cholangiocyte inflammatory response and portal myofibroblast proliferation

6 July 2018

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NAD(P)H oxidase mediates TGF-beta1-induced activation of kidney myofibroblasts

6 July 2018

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Hepatitis C Virus (HCV) Proteins Induce NADPH Oxidase 4 Expression in a Transforming Growth Factor -Dependent Manner: a New Contributor to HCV-Induced Oxidative Stress

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6 July 2018

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NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury.

6 July 2018

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6 July 2018

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Deficiency of nicotinamide adenine dinucleotide phosphate, reduced form oxidase enhances hepatocellular injury but attenuates fibrosis after chronic carbon tetrachloride administration

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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NAD(P)H oxidase 4 mediates transforming growth factor-beta1-induced differentiation of cardiac fibroblasts into myofibroblasts

6 July 2018

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The plasticity of p19 ARF null hepatic stellate cells and the dynamics of activation.

6 July 2018

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Reciprocal regulation of NADPH oxidases and the cyclooxygenase-2 pathway

6 July 2018

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The transforming growth factor-beta (TGF-β) mediates acquisition of a mesenchymal stem cell-like phenotype in human liver cells.

27 October 2018

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Role and cellular source of nicotinamide adenine dinucleotide phosphate oxidase in hepatic fibrosis

27 October 2018

1 reference

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The epithelial-to-mesenchymal transition in liver fibrosis: here today, gone tomorrow?

27 October 2018

1 reference

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Differential intracellular signalling induced by TGF-beta in rat adult hepatocytes and hepatoma cells: implications in liver carcinogenesis.

27 October 2018

1 reference

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Regurgitation of bile acids from leaky bile ducts causes sclerosing cholangitis in Mdr2 (Abcb4) knockout mice

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458844

Induction of heme oxygenase 1 prevents progression of liver fibrosis in Mdr2 knockout mice

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458844

Signal Transducer and Activator of Transcription 3 Protects From Liver Injury and Fibrosis in a Mouse Model of Sclerosing Cholangitis

9 December 2018

1 reference

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The epithelial mesenchymal transition confers resistance to the apoptotic effects of transforming growth factor Beta in fetal rat hepatocytes

9 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23049784

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Apoptosis Induced by Transforming Growth Factor- in Fetal Hepatocyte Primary Cultures

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23049784

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

NOX1/nicotinamide adenine dinucleotide phosphate, reduced form (NADPH) oxidase promotes proliferation of stellate cells and aggravates liver fibrosis induced by bile duct ligation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23049784

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0045285

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23049784 AND SRC:MED&resulttype=core&format=json

10 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23049784 AND SRC:MED&resulttype=core&format=json

10 March 2020

PubMed publication ID

23049784

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23049784 AND SRC:MED&resulttype=core&format=json