A novel positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterization. (Q34414363)

PubMed publication ID

15858066

2 August 2017

title

A novel positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterization (English)

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12 May 2020

author name string

Raymond S Hurst

1

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12 May 2020

Mihaly Hajós

2

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12 May 2020

Mario Raggenbass

3

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12 May 2020

Theron M Wall

4

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12 May 2020

Nicole R Higdon

5

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12 May 2020

Judy A Lawson

6

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12 May 2020

Karen L Rutherford-Root

7

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12 May 2020

Mitchell B Berkenpas

8

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12 May 2020

W E Hoffmann

9

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12 May 2020

David W Piotrowski

10

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12 May 2020

Vincent E Groppi

11

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12 May 2020

Geraldine Allaman

12

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Roch Ogier

13

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Sonia Bertrand

14

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12 May 2020

Daniel Bertrand

15

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Stephen P Arneric

16

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language of work or name

English

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publication date

1 April 2005

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PubMed publication ID

15858066

2 August 2017

published in

Journal of Neuroscience

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12 May 2020

volume

25

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issue

17

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12 May 2020

page(s)

4396-4405

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Choline and selective antagonists identify two subtypes of nicotinic acetylcholine receptors that modulate GABA release from CA1 interneurons in rat hippocampal slices.

12 May 2020

cites work

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Allosteric modulation of nicotinic receptors as a treatment strategy for Alzheimer's disease

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Long-lasting facilitation of 4-amino-n-[2,3-(3)H]butyric acid ([(3)H]GABA) release from rat hippocampal slices by nicotinic receptor activation

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Modulation of nicotinic receptor activity in the central nervous system: a novel approach to the treatment of Alzheimer disease

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alpha7 nicotinic acetylcholine receptors on GABAergic interneurons evoke dendritic and somatic inhibition of hippocampal neurons

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Ventral hippocampal alpha 7 nicotinic receptor blockade and chronic nicotine effects on memory performance in the radial-arm maze

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5-Hydroxyindole potentiates human alpha 7 nicotinic receptor-mediated responses and enhances acetylcholine-induced glutamate release in cerebellar slices

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Desensitization of neuronal nicotinic receptors

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Potentiation of alpha7-containing nicotinic acetylcholine receptors by select albumins

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DMXB, an alpha7 nicotinic agonist, normalizes auditory gating in isolation-reared rats

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Mecamylamine reversal by nicotine and by a partial alpha7 nicotinic acetylcholine receptor agonist (GTS-21) in rabbits tested with delay eyeblink classical conditioning

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Identification of SLURP-1 as an epidermal neuromodulator explains the clinical phenotype of Mal de Meleda

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Chronic transdermal nicotine patch treatment effects on cognitive performance in age-associated memory impairment

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12 December 2020

The nicotinic acetylcholine receptor subtypes and their function in the hippocampus and cerebral cortex

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AR-R 17779 improves social recognition in rats by activation of nicotinic alpha7 receptors

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Nicotinic acetylcholine receptors as drug targets

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Evidence of association between smoking and alpha7 nicotinic receptor subunit gene in schizophrenia patients

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Effects of nicotine on cognitive deficits in schizophrenia

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AMPA receptor potentiators for the treatment of CNS disorders

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Alpha-7 nicotinic receptor agonists: potential new candidates for the treatment of schizophrenia

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Bioactivity of a peptide derived from acetylcholinesterase: involvement of an ivermectin-sensitive site on the alpha 7 nicotinic receptor

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12 December 2020

The selective alpha7 nicotinic acetylcholine receptor agonist PNU-282987 [N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]-4-chlorobenzamide hydrochloride] enhances GABAergic synaptic activity in brain slices and restores auditory gating deficits in anesthetize

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A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-BTX

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Unconventional pharmacology of a neuronal nicotinic receptor mutated in the channel domain

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12 December 2020

A nicotinic agonist (GTS-21), eyeblink classical conditioning, and nicotinic receptor binding in rabbit brain

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12 December 2020

Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. I. Pharmacological and functional evidence for distinct structural subtypes.

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

Normalizing Effects of Nicotine and a Novel Nicotinic Agonist on Hippocampal Auditory Gating in Two Animal Models

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Neuronal nicotinic acetylcholine receptor activation modulates gamma-aminobutyric acid release from CA1 neurons of rat hippocampal slices

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Acetylcholine Activates an α-Bungarotoxin-Sensitive Nicotinic Current in Rat Hippocampal Interneurons, But Not Pyramidal Cells

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Ivermectin: A Positive Allosteric Effector of the α7 Neuronal Nicotinic Acetylcholine Receptor

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Presynaptic Nicotinic Receptors Facilitate Monoaminergic Transmission

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Selective alpha7-nicotinic agonists normalize inhibition of auditory response in DBA mice.

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10.1523/JNEUROSCI.5269-04.2005

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725110&resulttype=core&format=json

12 May 2020

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12 May 2020

PubMed publication ID

15858066

1 reference