Mechanisms of chromosomal translocations in B cell lymphomas (Q34405423)

2 August 2017

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title

Mechanisms of chromosomal translocations in B cell lymphomas (English)

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ORCID Public Data File 2021

2 August 2017

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author name string

Küppers R

series ordinal

1

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2 August 2017

Dalla-Favera R

series ordinal

2

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2 August 2017

language of work or name

English

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publication date

1 September 2001

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2 August 2017

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2 August 2017

volume

20

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2 August 2017

issue

40

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2 August 2017

page(s)

5580-5863

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The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

2 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Disruption of the human SCL locus by "illegitimate" V-(D)-J recombinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Mechanism of the t(14;18) chromosomal translocation: structural analysis of both derivative 14 and 18 reciprocal partners

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Identification of the gene associated with the recurring chromosomal translocations t(3;14)(q27;q32) and t(3;22)(q27;q11) in B-cell lymphomas

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Maturation of the immune response in germinal centers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

DNA Double-Strand Breaks in Immunoglobulin Genes Undergoing Somatic Hypermutation

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

The IgG Fc receptor, FcgammaRIIB, is a target for deregulation by chromosomal translocation in malignant lymphoma

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Deregulation of BCL6 in non-Hodgkin lymphoma by insertion of IGH sequences in complex translocations involving band 3q27.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Frequent translocation t(4;14)(p16.3;q32.3) in multiple myeloma is associated with increased expression and activating mutations of fibroblast growth factor receptor 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Th2-dependent B cell responses in the absence of CD40-CD40 ligand interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Translocation t(14;18) in B cell lymphomas as a cause for defective immunoglobulin production

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Burkitt lymphoma cell line carrying a variant translocation creates new DNA at the breakpoint and violates the hierarchy of immunoglobulin gene rearrangement

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

The RAG proteins and V(D)J recombination: complexes, ends, and transposition

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Somatic hypermutation in the heavy chain locus correlates with transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Insertion of excised IgH switch sequences causes overexpression of cyclin D1 in a myeloma tumor cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Antigen-independent appearance of recombination activating gene (RAG)-positive bone marrow B cells in the spleens of immunized mice

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Identification of reciprocal translocation sites within the c-myc oncogene and immunoglobulin mu locus in a Burkitt lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

RAG1 and RAG2 expression by B cell subsets from human tonsil and peripheral blood.

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Modifying the sequence of an immunoglobulin V-gene alters the resulting pattern of hypermutation

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

The t(8; 14) chromosomal translocation occurring in B-cell malignancies results from mistakes in V-D-J joining

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Generation of a variant t(2;8) translocation of Burkitt's lymphoma by site-specific recombination via the kappa light-chain joining signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

IRTA1 and IRTA2, novel immunoglobulin superfamily receptors expressed in B cells and involved in chromosome 1q21 abnormalities in B cell malignancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Three breakpoints of variant t(2;8) translocations in Burkitt's lymphoma cells fall within a region 140 kilobases distal from c-myc

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

DNA transposition by the RAG1 and RAG2 proteins: a possible source of oncogenic translocations

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Deregulation of MUM1/IRF4 by chromosomal translocation in multiple myeloma

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Switch recombination in normal IgA1 B lymphocytes

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Malignant lymphomas with a follicular growth pattern

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Intraclonal generation of antibody mutants in germinal centres

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Hodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Genetic recombination in a chromosomal translocation t(2;8)(p11;q24) of a Burkitt's lymphoma cell line, KOBK101.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Lessons from hereditary colorectal cancer

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Lymphocyte-specific genomic instability and risk of lymphoid malignancy

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Somatic hypermutation in normal and transformed human B cells

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Human immunoglobulin (Ig)M IgD peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

N segment insertion and region-directed somatic hypermutation in a kappa gene of a t(2;8) chromosomal translocation

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Cellular origin of human B-cell lymphomas.

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

THE ORIGIN OF HODGKIN AND REED/STERNBERG CELLS IN HODGKIN'S DISEASE

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death.

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

The regulated expression of B lineage associated genes during B cell differentiation in bone marrow and fetal liver

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Within germinal centers, isotype switching of immunoglobulin genes occurs after the onset of somatic mutation

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Immunoglobulin class switch recombination: will genetics provide new clues to mechanism?

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

The T-cell-independent immune response to the hapten NP uses a large repertoire of heavy chain genes

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Antigen receptor engagement turns off the V(D)J recombination machinery in human tonsil B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

New type of t(14;18) in a non-Hodgkin's lymphoma provides insight in molecular events in early B-cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Frequent somatic hypermutation of the 5' noncoding region of the BCL6 gene in B-cell lymphoma

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Persistence of immunoglobulin heavy chain/c-myc recombination-positive lymphocyte clones in the blood of human immunodeficiency virus-infected homosexual men

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Somatic mutation of the CD95 gene in human B cells as a side-effect of the germinal center reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Different regions of the immunoglobulin heavy-chain locus are involved in chromosomal translocations in distinct pathogenetic forms of Burkitt lymphoma

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

B cell lymphoma-associated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-kappa B p50

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

21 January 2018

Somatic hypermutation

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

V(D)J Recombination in Mature B Cells: A Mechanism for Altering Antibody Responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Cell-cycle-regulated DNA double-stranded breaks in somatic hypermutation of immunoglobulin genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Clonal selection and learning in the antibody system

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Chromosomal translocations deregulating c-myc are associated with normal immune responses

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Diverse karyotypic abnormalities of the c-myc locus associated with c-myc dysregulation and tumor progression in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Cloning and sequencing of a c-myc oncogene in a Burkitt's lymphoma cell line that is translocated to a germ line alpha switch region

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

A uniform deleting element mediates the loss of kappa genes in human B cells

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Somatic generation of antibody diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

The t(14;18) chromosome translocations involved in B-cell neoplasms result from mistakes in VDJ joining

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

T cell receptor gene trans-rearrangements: chimeric gamma-delta genes in normal lymphoid tissues

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

CD40-CD40L independent Ig gene hypermutation suggests a second B cell diversification pathway in humans

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Bcl10 is involved in t(1;14)(p22;q32) of MALT B cell lymphoma and mutated in multiple tumor types

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

BCL2 oncogene translocation is mediated by a chi-like consensus

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Inactivating mutations and overexpression of BCL10, a caspase recruitment domain-containing gene, in MALT lymphoma with t(1;14)(p22;q32)

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

The genetics of childhood acute lymphoblastic leukaemia

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

A variant translocation places the λ immunoglobulin genes 3′ to the c-myc oncogene in Burkitt's lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14;18)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Continued RAG expression in late stages of B cell development and no apparent re-induction after immunizion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

7 January 2021

Site-specific recombination of the tal-1 gene is a common occurrence in human T cell leukemia

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

7 January 2021

Variant translocations in sporadic Burkitt's lymphoma detected in fresh tumour material: analysis of three cases

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

7 January 2021

Translocation and rearrangements of the c-myc oncogene locus in human undifferentiated B-cell lymphomas

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

7 January 2021

CD19-deficient mice exhibit poor responsiveness to oral immunization despite evidence of unaltered total IgA levels, germinal centers and IgA-isotype switching in Peyer's patches

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

7 January 2021

V(D)J Recombinase Activity in a Subset of Germinal Center B Lymphocytes

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

7 January 2021

Molecular Mechanism of the t(14;18)—A Model for Lymphoid-Specific Chromosomal Translocations

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

7 January 2021

Role of lymphotoxin and the type I TNF receptor in the formation of germinal centers

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

7 January 2021

Circulating human B cells that express surrogate light chains and edited receptors

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

7 January 2021

Somatic hypermutation of immunoglobulin genes is linked to transcription initiation

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https://api.crossref.org/works/10.1038/SJ.ONC.1204640

7 January 2021

VDJ recombination: a transposase goes to work

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

7 January 2021

Frequency of the Bcl-2/IgH rearrangement in normal individuals: implications for the monitoring of disease in patients with follicular lymphoma

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

7 January 2021

Identification of heterologous translocation partner genes fused to the BCL6 gene in diffuse large B-cell lymphomas: 5'-RACE and LA - PCR analyses of biopsy samples

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1204640

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204640

1 reference

Dimensions Publication ID

2 August 2017

1019518992

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1 reference