SGLT2 inhibitors act from the extracellular surface of the cell membrane (Q34400029)

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21 March 2020

title

SGLT2 inhibitors act from the extracellular surface of the cell membrane (English)

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21 March 2020

1

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21 March 2020

Edurne Gorraitz

3

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21 March 2020

author name string

Bruce A Hirayama

2

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21 March 2020

Donald D F Loo

4

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21 March 2020

Yin Liang

5

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21 March 2020

Ernest M Wright

6

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21 March 2020

publication date

27 June 2014

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21 March 2020

published in

Physiological Reports

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21 March 2020

volume

2

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21 March 2020

issue

6

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Metabolism and excretion of canagliflozin in mice, rats, dogs, and humans.

21 March 2020

cites work

1 reference

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Pharmacokinetic and pharmacodynamic profile of empagliflozin, a sodium glucose co-transporter 2 inhibitor

6 July 2018

1 reference

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Increase in SGLT1-mediated transport explains renal glucose reabsorption during genetic and pharmacological SGLT2 inhibition in euglycemia.

6 July 2018

1 reference

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Clinical pharmacokinetics and pharmacodynamics of dapagliflozin, a selective inhibitor of sodium-glucose co-transporter type 2.

6 July 2018

1 reference

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C-Glucosides with heteroaryl thiophene as novel sodium-dependent glucose cotransporter 2 inhibitors

6 July 2018

1 reference

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Pharmacokinetics and pharmacodynamics of canagliflozin, a sodium glucose co-transporter 2 inhibitor, in subjects with type 2 diabetes mellitus

6 July 2018

1 reference

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Regulation of the human Na -dependent glucose cotransporter hSGLT2.

6 July 2018

1 reference

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Efficacy and safety of SGLT2 inhibitors in the treatment of type 2 diabetes mellitus

6 July 2018

1 reference

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Structural selectivity of human SGLT inhibitors

6 July 2018

1 reference

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Biology of Human Sodium Glucose Transporters

6 July 2018

1 reference

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Glucose transport by human renal Na /D-glucose cotransporters SGLT1 and SGLT2

6 July 2018

1 reference

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Sodium-glucose transport: role in diabetes mellitus and potential clinical implications.

6 July 2018

1 reference

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Dapagliflozin, a selective SGLT2 inhibitor, improves glucose homeostasis in normal and diabetic rats

6 July 2018

1 reference

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THE ACTION OF PHLORIZIN ON THE EXCRETION OF GLUCOSE, XYLOSE, SUCROSE, CREATININE AND UREA BY MAN.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208661

Kinetics of the reverse mode of the Na /glucose cotransporter

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208661

The in vivo localization of high-affinity phlorizin receptors to the brush border surface of the proximal tubule in dog kidney

6 July 2018

1 reference

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Intestinal Na /glucose cotransporter expressed in Xenopus oocytes is electrogenic

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208661

Discovery of canagliflozin, a novel C-glucoside with thiophene ring, as sodium-dependent glucose cotransporter 2 inhibitor for the treatment of type 2 diabetes mellitus.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208661

In vitro characterization and pharmacokinetics of dapagliflozin (BMS-512148), a potent sodium-glucose cotransporter type II inhibitor, in animals and humans

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208661

Dapagliflozin, a novel, selective SGLT2 inhibitor, improved glycemic control over 2 weeks in patients with type 2 diabetes mellitus

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208661

How drugs interact with transporters: SGLT1 as a model

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208661

Kinetic and specificity differences between rat, human, and rabbit Na -glucose cotransporters (SGLT-1).

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208661

Empagliflozin (BI 10773), a Potent and Selective SGLT2 Inhibitor, Induces Dose-Dependent Glucosuria in Healthy Subjects

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24973332

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.14814/PHY2.12058

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21 March 2020

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21 March 2020

PubMed publication ID

24973332

1 reference

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