p53-mediated apoptosis requires inositol hexakisphosphate kinase-2 (Q34397020)

1 August 2017

title

p53-mediated apoptosis requires inositol hexakisphosphate kinase-2 (English)

1 reference

DOI

10.1073/PNAS.1015671107

https://api.crossref.org/works/10.1073/PNAS.1015671107

27 August 2024

1 reference

Solomon Halbert Snyder

9

object named as

Solomon H Snyder

1 reference

1 August 2017

1

Michael A Koldobskiy

1 reference

1 August 2017

6

M Scott Vandiver

1 reference

1 August 2017

3

J. Kent Werner

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21078964

27 August 2024

author name string

Anutosh Chakraborty

2

1 reference

1 August 2017

Seyun Kim

7

1 reference

1 August 2017

Shira Heletz

8

1 reference

1 August 2017

Adele M. Snowman

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21078964

27 August 2024

Krishna R. Juluri

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21078964

27 August 2024

language of work or name

English

0 references

publication date

15 November 2010

1 reference

full work available at URL

1 August 2017

https://europepmc.org/articles/pmc3000257?pdf=render

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21078964

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21078964/?tool=EBI

27 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21078964

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21078964/pdf/?tool=EBI

27 August 2024

file format

Portable Document Format

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21078964

https://europepmc.org/articles/PMC3000257

27 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21078964

https://europepmc.org/articles/PMC3000257?pdf=render

27 August 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21078964

https://doi.org/10.1073/pnas.1015671107

27 August 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21078964

https://pnas.org/doi/pdf/10.1073/pnas.1015671107

27 August 2024

1 reference

DOI

10.1073/PNAS.1015671107

https://api.crossref.org/works/10.1073/PNAS.1015671107

Proceedings of the National Academy of Sciences of the United States of America

27 August 2024

published in

1 reference

1 August 2017

volume

107

1 reference

1 August 2017

issue

49

1 reference

1 August 2017

page(s)

20947-20951

1 reference

1 August 2017

cites work

Modes of p53 regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

Gene deletion of inositol hexakisphosphate kinase 2 predisposes to aerodigestive tract carcinoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

Blinded by the Light: The Growing Complexity of p53

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

Gene deletion of inositol hexakisphosphate kinase 1 reveals inositol pyrophosphate regulation of insulin secretion, growth, and spermiogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

HSP90 regulates cell survival via inositol hexakisphosphate kinase-2.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

Requirement of inositol pyrophosphates for full exocytotic capacity in pancreatic beta cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

Hzf Determines cell survival upon genotoxic stress by modulating p53 transactivation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

A conserved family of enzymes that phosphorylate inositol hexakisphosphate

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

The multiple battles fought by anti-apoptotic p21.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

Understanding the biological significance of diphosphoinositol polyphosphates ('inositol pyrophosphates').

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

The p53 family in nervous system development and disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

p53 in recombination and repair

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

Inositol pyrophosphates regulate cell death and telomere length through phosphoinositide 3-kinase-related protein kinases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

Apo2L/TRAIL induction and nuclear translocation of inositol hexakisphosphate kinase 2 during IFN-beta-induced apoptosis in ovarian carcinoma.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

Inositol hexakisphosphate kinase-2, a physiologic mediator of cell death

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

Integral role of Noxa in p53-mediated apoptotic response

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

PUMA mediates the apoptotic response to p53 in colorectal cancer cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

Cell cycle regulation and p53 activation by protein phosphatase 2C alpha

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

Inositol pyrophosphates regulate endocytic trafficking

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

Inositol hexakisphosphate kinase 2 sensitizes ovarian carcinoma cells to multiple cancer therapeutics

6 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

6 July 2018

https://api.crossref.org/works/10.1073/PNAS.1015671107

ASPP proteins specifically stimulate the apoptotic function of p53

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

PUMA, a novel proapoptotic gene, is induced by p53

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

Inositol hexakisphosphate kinase 2 mediates growth suppressive and apoptotic effects of interferon-beta in ovarian carcinoma cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

Back in the water: the return of the inositol phosphates

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

Role of BAX in the apoptotic response to anticancer agents

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

Synthesis of diphosphoinositol pentakisphosphate by a newly identified family of higher inositol polyphosphate kinases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

Disruption of p53 in human cancer cells alters the responses to therapeutic agents

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

p53 is required for radiation-induced apoptosis in mouse thymocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

p21 is necessary for the p53-mediated G1 arrest in human cancer cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

Inositol pyrophosphates mediate chemotaxis in Dictyostelium via pleckstrin homology domain-PtdIns(3,4,5)P3 interactions

6 July 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.1015671107

Inositol diphosphate signaling regulates telomere length

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.1015671107

Regulation of a cyclin-CDK-CDK inhibitor complex by inositol pyrophosphates

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.1015671107

p53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000257

Myc suppression of the p21 Cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage

27 October 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.1015671107

21 January 2018

Identifiers

DOI

10.1073/PNAS.1015671107

1 reference

release_s3n7thrfijfqzgsptv4rlk4tja

1 August 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/s3n7thrfijfqzgsptv4rlk4tja

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

3000257

1 reference

1 August 2017

1 reference