SIRT4 regulates ATP homeostasis and mediates a retrograde signaling via AMPK. (Q34389269)

1 August 2017

title

SIRT4 regulates ATP homeostasis and mediates a retrograde signaling via AMPK. (English)

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1 August 2017

10

Eric Verdin

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1 August 2017

Linh Ho

1

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1 August 2017

Allen Sam Titus

2

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1 August 2017

Kushal Kr Banerjee

3

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1 August 2017

Suji George

4

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1 August 2017

Wei Lin

5

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1 August 2017

Shaunak Deota

6

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1 August 2017

Asish K Saha

7

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1 August 2017

Ken Nakamura

8

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1 August 2017

Philipp Gut

9

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1 August 2017

Ullas Kolthur-Seetharam

11

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1 August 2017

publication date

1 November 2013

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1 August 2017

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1 August 2017

volume

5

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1 August 2017

issue

11

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1 August 2017

page(s)

835-849

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Implications of mitochondrial uncoupling in skeletal muscle in the development and treatment of obesity

1 August 2017

cites work

1 reference

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SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase

6 July 2018

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The mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4

6 July 2018

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SIRT4 has tumor-suppressive activity and regulates the cellular metabolic response to DNA damage by inhibiting mitochondrial glutamine metabolism

6 July 2018

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SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine

6 July 2018

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6 July 2018

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6 July 2018

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Augmenting energy expenditure by mitochondrial uncoupling: a role of AMP-activated protein kinase

6 July 2018

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Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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SIRT4 Regulates Fatty Acid Oxidation and Mitochondrial Gene Expression in Liver and Muscle Cells

6 July 2018

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Downregulation of AMPK accompanies leucine- and glucose-induced increases in protein synthesis and insulin resistance in rat skeletal muscle

6 July 2018

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6 July 2018

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Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity

6 July 2018

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AMPK in Health and Disease

6 July 2018

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Transcriptional control of mitochondrial biogenesis and function

6 July 2018

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AMPK regulates energy expenditure by modulating NAD metabolism and SIRT1 activity

6 July 2018

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SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span

6 July 2018

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The NAD World: a new systemic regulatory network for metabolism and aging--Sirt1, systemic NAD biosynthesis, and their importance

6 July 2018

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A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis

6 July 2018

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Malonyl-CoA, a key signaling molecule in mammalian cells

6 July 2018

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The ADP and ATP transport in mitochondria and its carrier

6 July 2018

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Conserved metabolic regulatory functions of sirtuins

6 July 2018

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Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase

6 July 2018

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SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells

6 July 2018

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Carboxyatractyloside effects on brown-fat mitochondria imply that the adenine nucleotide translocator isoforms ANT1 and ANT2 may be responsible for basal and fatty-acid-induced uncoupling respectively.

6 July 2018

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Mitochondrial retrograde signaling

6 July 2018

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Genomic instability and aging-like phenotype in the absence of mammalian SIRT6

6 July 2018

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6 July 2018

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6 July 2018

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PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis

6 July 2018

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Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

6 July 2018

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SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes

6 July 2018

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Mitochondrial signaling: the retrograde response

6 July 2018

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The adenine nucleotide translocase: a central component of the mitochondrial permeability transition pore and key player in cell death.

6 July 2018

1 reference

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Mitochondrial ATP synthasome. Cristae-enriched membranes and a multiwell detergent screening assay yield dispersed single complexes containing the ATP synthase and carriers for Pi and ADP/ATP.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3868726

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

6 July 2018

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The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3868726

Malonyl-CoA and the regulation of fatty acid oxidation in soleus muscle

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3868726

The mitochondrial ADP/ATP carrier: structural, physiological and pathological aspects.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3868726

Tissue-specific transcription pattern of the adenine nucleotide translocase isoforms in humans.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3868726

The AMP-activated protein kinase--fuel gauge of the mammalian cell?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3868726

Dependence of mitochondrial oxidative phosphorylation on activity of the adenine nucleotide translocase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3868726

Identification by amino acid sequencing of three major regulatory phosphorylation sites on rat acetyl-CoA carboxylase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3868726

Phosphorylation of rat muscle acetyl-CoA carboxylase by AMP-activated protein kinase and protein kinase A

6 July 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24296486

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Direct thyroid hormone signalling via ADP-ribosylation controls mitochondrial nucleotide transport and membrane leakiness by changing the conformation of the adenine nucleotide transporter

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24296486

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The reconstituted ADP/ATP carrier can mediate H transport by free fatty acids, which is further stimulated by mersalyl

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24296486

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.18632/AGING.100616

0 references

PMC publication ID

3868726

1 reference

1 August 2017

1 reference