Role of periostin, FENO, IL-13, lebrikzumab, other IL-13 antagonist and dual IL-4/IL-13 antagonist in asthma (Q34388348)

1 August 2017

title

Role of periostin, FENO, IL-13, lebrikzumab, other IL-13 antagonist and dual IL-4/IL-13 antagonist in asthma (English)

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1 August 2017

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Swati Agrawal

1

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1 August 2017

Robert G Townley

series ordinal

2

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1 August 2017

language of work or name

English

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publication date

28 November 2013

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Expert Opinion on Biological Therapy

1 August 2017

published in

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1 August 2017

volume

14

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1 August 2017

issue

2

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1 August 2017

page(s)

165-181

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Omalizumab for pediatric asthma

1 August 2017

cites work

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Severe asthma: future treatments.

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Interleukin-13: central mediator of allergic asthma

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Requirement for IL-13 independently of IL-4 in experimental asthma

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Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

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Redefining approaches to asthma: developing targeted biologic therapies.

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Interleukin-13 in asthma pathogenesis

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Blockade of interleukin-13-mediated cell activation by a novel inhibitory antibody to human IL-13 receptor alpha1.

21 January 2018

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Interleukin 13 and the beta-adrenergic blockade theory of asthma revisited 40 years later

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Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and -12 in IL-13-induced inflammation and remodeling

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IL-13 receptors and signaling pathways: An evolving web

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Role of CCR5 in the pathogenesis of IL-13-induced inflammation and remodeling

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Increased sputum and bronchial biopsy IL-13 expression in severe asthma

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Effect of interleukin 13 on bronchial hyperresponsiveness and the bronchoprotective effect of beta-adrenergic bronchodilators and corticosteroids

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Airway remodeling and lack of bronchodilator response in steroid-resistant asthma

21 January 2018

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Dysregulation of interleukin 4, interleukin 5, and interferon gamma gene expression in steroid-resistant asthma

21 January 2018

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Glucocorticoid resistance in inflammatory diseases.

21 January 2018

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Relative corticosteroid insensitivity of peripheral blood mononuclear cells in severe asthma

21 January 2018

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Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program

21 January 2018

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Steroid-resistant asthma. Cellular mechanisms contributing to inadequate response to glucocorticoid therapy

21 January 2018

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Steroid-unresponsive asthma

21 January 2018

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21 January 2018

Steroid-resistant asthma

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Osteoblast-specific factor 2: cloning of a putative bone adhesion protein with homology with the insect protein fasciclin I

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Periostin: a novel component of subepithelial fibrosis of bronchial asthma downstream of IL-4 and IL-13 signals.

21 January 2018

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Human periostin gene expression in normal tissues, tumors and melanoma: evidences for periostin production by both stromal and melanoma cells

21 January 2018

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Identification and characterization of a novel protein, periostin, with restricted expression to periosteum and periodontal ligament and increased expression by transforming growth factor beta

21 January 2018

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Phosphatidylinositol-3-kinase signaling mediates vascular smooth muscle cell expression of periostin in vivo and in vitro

21 January 2018

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Origin of cardiac fibroblasts and the role of periostin

21 January 2018

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Matricellular proteins in cardiac adaptation and disease

21 January 2018

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Expression of Periostin, homologous with an insect cell adhesion molecule, as a prognostic marker in non-small cell lung cancers.

21 January 2018

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Periostin regulates collagen fibrillogenesis and the biomechanical properties of connective tissues

21 January 2018

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Spatiotemporal expression of periostin during skin development and incisional wound healing: lessons for human fibrotic scar formation

21 January 2018

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Roles of epithelial cell-derived periostin in TGF-beta activation, collagen production, and collagen gel elasticity in asthma

21 January 2018

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Delayed re-epithelialization in periostin-deficient mice during cutaneous wound healing.

21 January 2018

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Periostin, a matricellular protein, accelerates cutaneous wound repair by activating dermal fibroblasts.

21 January 2018

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Periostin promotes chronic allergic inflammation in response to Th2 cytokines.

21 January 2018

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https://api.crossref.org/works/10.1517/14712598.2014.859673

A protective role for periostin and TGF-β in IgE-mediated allergy and airway hyperresponsiveness

21 January 2018

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https://api.crossref.org/works/10.1517/14712598.2014.859673

Periostin facilitates eosinophil tissue infiltration in allergic lung and esophageal responses

21 January 2018

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https://api.crossref.org/works/10.1517/14712598.2014.859673

Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids

21 January 2018

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https://api.crossref.org/works/10.1517/14712598.2014.859673

Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients

21 January 2018

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https://api.crossref.org/works/10.1517/14712598.2014.859673

T-helper type 2-driven inflammation defines major subphenotypes of asthma.

21 January 2018

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https://api.crossref.org/works/10.1517/14712598.2014.859673

Lebrikizumab Treatment in Adults with Asthma

21 January 2018

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https://api.crossref.org/works/10.1517/14712598.2014.859673

IL-13 in asthma and allergic disease: asthma phenotypes and targeted therapies

21 January 2018

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https://api.crossref.org/works/10.1517/14712598.2014.859673

Structural basis of signaling blockade by anti-IL-13 antibody Lebrikizumab

21 January 2018

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https://api.crossref.org/works/10.1517/14712598.2014.859673

Dose-ranging study of lebrikizumab in asthmatic patients not receiving inhaled steroids

21 January 2018

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https://api.crossref.org/works/10.1517/14712598.2014.859673

An IL-4/IL-13 dual antagonist reduces lung inflammation, airway hyperresponsiveness, and IgE production in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2014.859673

Development of a human IgG4 bispecific antibody for dual targeting of interleukin-4 (IL-4) and interleukin-13 (IL-13) cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2014.859673

IL-4 and IL-13 dual antagonism: a promising approach to the dilemma of generating effective asthma biotherapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2014.859673

A phase II placebo-controlled study of tralokinumab in moderate-to-severe asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2014.859673

IL-4 receptor polymorphisms predict reduction in asthma exacerbations during response to an anti-IL-4 receptor α antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2014.859673

Effect of hydrocortisone on beta-adrenergic receptors in lung membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2014.859673

Airway hyperresponsiveness: a story of mice and men and cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2014.859673

IL-13 induced increases in nitrite levels are primarily driven by increases in inducible nitric oxide synthase as compared with effects on arginases in human primary bronchial epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2014.859673

Nitric oxide gas phase release in human small airway epithelial cells

21 January 2018

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https://api.crossref.org/works/10.1517/14712598.2014.859673

Exhaled nitric oxide identifies the persistent eosinophilic phenotype in severe refractory asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2014.859673

An official ATS clinical practice guideline: interpretation of exhaled nitric oxide levels (FENO) for clinical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2014.859673

Inhibiting interleukin-4 and interleukin-13 in difficult-to-control asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2014.859673

Exhaled nitric oxide in children with asthma receiving Xolair (omalizumab), a monoclonal anti-immunoglobulin E antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2014.859673

The anti-IgE antibody omalizumab reduces exacerbations and steroid requirement in allergic asthmatics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2014.859673

G Protein βγ-subunit signaling mediates airway hyperresponsiveness and inflammation in allergic asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2014.859673

IL-33-responsive lineage- CD25 CD44(hi) lymphoid cells mediate innate type 2 immunity and allergic inflammation in the lungs

21 January 2018

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https://api.crossref.org/works/10.1517/14712598.2014.859673

Efficient cytokine-induced IL-13 production by mast cells requires both IL-33 and IL-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14712598.2014.859673

10.1517/14712598.2014.859673

21 January 2018

Identifiers

DOI

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1 August 2017

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