Proteopathic tau seeding predicts tauopathy in vivo. (Q34383788)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25261551 AND SRC:MED&resulttype=core&format=json

20 February 2020

title

Proteopathic tau seeding predicts tauopathy in vivo (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25261551 AND SRC:MED&resulttype=core&format=json

20 February 2020

0 references

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25261551 AND SRC:MED&resulttype=core&format=json

20 February 2020

Thomas E. Mahan

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25261551 AND SRC:MED&resulttype=core&format=json

20 February 2020

9

David M Holtzman

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25261551 AND SRC:MED&resulttype=core&format=json

20 February 2020

8

Nigel J Cairns

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25261551 AND SRC:MED&resulttype=core&format=json

20 February 2020

author name string

Jennifer L Furman

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25261551 AND SRC:MED&resulttype=core&format=json

20 February 2020

Tritia R Yamasaki

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25261551 AND SRC:MED&resulttype=core&format=json

20 February 2020

Hilda Mirbaha

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25261551 AND SRC:MED&resulttype=core&format=json

20 February 2020

William C Eades

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25261551 AND SRC:MED&resulttype=core&format=json

20 February 2020

Larisa Belaygorod

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25261551 AND SRC:MED&resulttype=core&format=json

20 February 2020

Marc I Diamond

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25261551 AND SRC:MED&resulttype=core&format=json

20 February 2020

language of work or name

English

0 references

publication date

26 September 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25261551 AND SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

20 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25261551 AND SRC:MED&resulttype=core&format=json

20 February 2020

volume

111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25261551 AND SRC:MED&resulttype=core&format=json

20 February 2020

issue

41

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25261551 AND SRC:MED&resulttype=core&format=json

20 February 2020

page(s)

E4376-85

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25261551 AND SRC:MED&resulttype=core&format=json

describes a project that uses

20 February 2020

Tau RD P301S FRET Biosensor

0 references

cites work

Prion-like properties of Tau protein: the importance of extracellular Tau as a therapeutic target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

Distinct tau prion strains propagate in cells and mice and define different tauopathies

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

Neuronal activity regulates extracellular tau in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: relevance to sporadic tauopathies

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

Extracellular monomeric tau protein is sufficient to initiate the spread of tau protein pathology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

Distinct α-synuclein strains differentially promote tau inclusions in neurons

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

Brain homogenates from human tauopathies induce tau inclusions in mouse brain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

Synthetic tau fibrils mediate transmission of neurofibrillary tangles in a transgenic mouse model of Alzheimer's-like tauopathy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

Small misfolded Tau species are internalized via bulk endocytosis and anterogradely and retrogradely transported in neurons

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

Prion seeding activities of mouse scrapie strains with divergent PrPSc protease sensitivities and amyloid plaque content using RT-QuIC and eQuIC

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

Trans-cellular propagation of Tau aggregation by fibrillar species

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

Predicting regional neurodegeneration from the healthy brain functional connectome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

A Network Diffusion Model of Disease Progression in Dementia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

Propagation of tau pathology in a model of early Alzheimer's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

Trans-synaptic spread of tau pathology in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

Protein misfolding detected early in pathogenesis of transgenic mouse model of Huntington disease using amyloid seeding assay

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: a practical approach

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

P301S mutant human tau transgenic mice manifest early symptoms of human tauopathies with dementia and altered sensorimotor gating

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

Seeding of normal Tau by pathological Tau conformers drives pathogenesis of Alzheimer-like tangles

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

A kinetic aggregation assay allowing selective and sensitive amyloid-β quantification in cells and tissues

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

A flow cytometry-based FRET assay to identify and analyse protein-protein interactions in living cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

Interneuronal transfer of human tau between Lamprey central neurons in situ

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

Prion-like mechanisms in neurodegenerative diseases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

Exogenous alpha-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

Transmission and spreading of tauopathy in transgenic mouse brain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

Neurodegenerative diseases target large-scale human brain networks

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

Propagation of tau misfolding from the outside to the inside of a cell.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

Prion detection by an amyloid seeding assay.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

A general model of prion strains and their pathogenicity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

Shattuck lecture--neurodegenerative diseases and prions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

Staging of Alzheimer's disease-related neurofibrillary changes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

Some Speculations about Prions, Amyloid, and Alzheimer's Disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

Structural characterization of the core of the paired helical filament of Alzheimer disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

The Topographical and Neuroanatomical Distribution of Neurofibrillary Tangles and Neuritic Plaques in the Cerebral Cortex of Patients with Alzheimer's Disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

Neuropathological stageing of Alzheimer-related changes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

A Rapid Cellular FRET Assay of Polyglutamine Aggregation Identifies a Novel Inhibitor

6 July 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.1411649111

Prion-like acceleration of a synucleinopathy in a transgenic mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.1411649111

Ultrasensitive detection of PrP(Sc) in the cerebrospinal fluid and blood of macaques infected with bovine spongiform encephalopathy prion

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.1411649111

Conformational change as one of the earliest alterations of tau in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.1411649111

Anti-tau antibodies that block tau aggregate seeding in vitro markedly decrease pathology and improve cognition in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.1411649111

Conformational features of tau fibrils from Alzheimer's disease brain are faithfully propagated by unmodified recombinant protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.1411649111

Initiation and Synergistic Fibrillization of Tau and Alpha-Synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.1411649111

Fibrillization of alpha-synuclein and tau in familial Parkinson's disease caused by the A53T alpha-synuclein mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.1411649111

Tau protein abnormalities associated with the progression of alzheimer disease type dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.1411649111

Monoclonal antibody AT8 recognises tau protein phosphorylated at both serine 202 and threonine 205.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.1411649111

Characteristics of the binding of thioflavin S to tau paired helical filaments.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

cAMP-dependent protein kinase phosphorylations on tau in Alzheimer's disease.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205609

FTDP-17: an early-onset phenotype with parkinsonism and epileptic seizures caused by a novel mutation

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25261551

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Detection of misfolded Aβ oligomers for sensitive biochemical diagnosis of Alzheimer's disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25261551

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1411649111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25261551 AND SRC:MED&resulttype=core&format=json

20 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25261551 AND SRC:MED&resulttype=core&format=json

20 February 2020

PubMed publication ID

25261551

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25261551 AND SRC:MED&resulttype=core&format=json