Activation of ATM and Chk2 kinases in relation to the amount of DNA strand breaks. (Q34347570)

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1 January 2020

title

Activation of ATM and Chk2 kinases in relation to the amount of DNA strand breaks (English)

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1

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1 January 2020

Paola Perego

2

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1 January 2020

author name string

Nives Carenini

3

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1 January 2020

Makoto Nakanishi

4

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1 January 2020

Luciana Chessa

5

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1 January 2020

Junjie Chen

6

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1 January 2020

Kumkum Khanna

7

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1 January 2020

Domenico Delia

8

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1 January 2020

language of work or name

English

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publication date

1 October 2004

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1 January 2020

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volume

23

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issue

46

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page(s)

7691-7700

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Questioning the role of checkpoint kinase 2 in the p53 DNA damage response

1 January 2020

cites work

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https://api.crossref.org/works/10.1038/SJ.ONC.1207986

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1207986

Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase I cleavage complexes.

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1207986

The Chk2 tumor suppressor is not required for p53 responses in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207986

Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1207986

Megabase chromatin domains involved in DNA double-strand breaks in vivo

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1207986

Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1207986

Polo-like kinase 1 and Chk2 interact and co-localize to centrosomes and the midbody

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1207986

Threonine 68 of Chk2 is phosphorylated at sites of DNA strand breaks

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.ONC.1207986

Autophosphorylation of checkpoint kinase 2 at serine 516 is required for radiation-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207986

Mammalian Polo-like kinase 3 (Plk3) is a multifunctional protein involved in stress response pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207986

7 January 2021

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

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https://api.crossref.org/works/10.1038/SJ.ONC.1207986

7 January 2021

Chk1 and Chk2 kinases in checkpoint control and cancer

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https://api.crossref.org/works/10.1038/SJ.ONC.1207986

7 January 2021

Levels of DNA strand breaks and superoxide in phorbol ester-treated human granulocytes

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https://api.crossref.org/works/10.1038/SJ.ONC.1207986

7 January 2021

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

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https://api.crossref.org/works/10.1038/SJ.ONC.1207986

7 January 2021

Nbs1 promotes ATM dependent phosphorylation events including those required for G1/S arrest

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https://api.crossref.org/works/10.1038/SJ.ONC.1207986

7 January 2021

DNA damage-induced activation of p53 by the checkpoint kinase Chk2

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https://api.crossref.org/works/10.1038/SJ.ONC.1207986

7 January 2021

Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex

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https://api.crossref.org/works/10.1038/SJ.ONC.1207986

7 January 2021

Inverse correlation between p53 protein levels and DNA repair efficiency in human fibroblast strains treated with 4-nitroquinoline 1-oxide: evidence that lesions other than DNA strand breaks trigger the p53 response

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207986

7 January 2021

AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching

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https://api.crossref.org/works/10.1038/SJ.ONC.1207986

7 January 2021

Role of human Cds1 (Chk2) kinase in DNA damage checkpoint and its regulation by p53

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https://api.crossref.org/works/10.1038/SJ.ONC.1207986

7 January 2021

Efficient rejoining of radiation-induced DNA double-strand breaks in vertebrate cells deficient in genes of the RAD52 epistasis group.

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https://api.crossref.org/works/10.1038/SJ.ONC.1207986

7 January 2021

Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1207986

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207986

1 reference

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Dimensions Publication ID

1 January 2020

1002293345

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1 reference

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