Podosome organization drives osteoclast-mediated bone resorption. (Q34344623)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24714644 AND SRC:MED&resulttype=core&format=json

13 March 2020

title

Podosome organization drives osteoclast-mediated bone resorption (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24714644 AND SRC:MED&resulttype=core&format=json

13 March 2020

2

1 reference

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13 March 2020

Anne Blangy

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24714644 AND SRC:MED&resulttype=core&format=json

13 March 2020

author name string

Dan Georgess

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24714644 AND SRC:MED&resulttype=core&format=json

13 March 2020

Pierre Jurdic

series ordinal

4

1 reference

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13 March 2020

publication date

1 May 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24714644 AND SRC:MED&resulttype=core&format=json

Cell Adhesion and Migration

13 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24714644 AND SRC:MED&resulttype=core&format=json

13 March 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24714644 AND SRC:MED&resulttype=core&format=json

13 March 2020

issue

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24714644 AND SRC:MED&resulttype=core&format=json

13 March 2020

page(s)

191-204

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Comparative transcriptomics reveals RhoE as a novel regulator of actin dynamics in bone-resorbing osteoclasts.

13 March 2020

cites work

1 reference

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Microtubule dynamic instability controls podosome patterning in osteoclasts through EB1, cortactin, and Src.

6 July 2018

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Hck contributes to bone homeostasis by controlling the recruitment of osteoclast precursors

6 July 2018

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Interplay between myosin IIA-mediated contractility and actin network integrity orchestrates podosome composition and oscillations

6 July 2018

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Dynamic visualization of RANKL and Th17-mediated osteoclast function.

6 July 2018

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Bone research in 2012: the ups and downs of bone in health and rheumatic disease

6 July 2018

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Talin1 and Rap1 are critical for osteoclast function

6 July 2018

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6 July 2018

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Identification, characterization, and isolation of a common progenitor for osteoclasts, macrophages, and dendritic cells from murine bone marrow and periphery

6 July 2018

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Cofilin activation during podosome belt formation in osteoclasts

6 July 2018

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Osteocyte control of osteoclastogenesis

6 July 2018

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Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin

6 July 2018

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New regulation mechanisms of osteoclast differentiation

6 July 2018

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Supervillin couples myosin-dependent contractility to podosomes and enables their turnover

6 July 2018

1 reference

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Involvement of actin polymerization in podosome dynamics

6 July 2018

1 reference

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TREM2 and β-catenin regulate bone homeostasis by controlling the rate of osteoclastogenesis

6 July 2018

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The pathogenesis of rheumatoid arthritis

6 July 2018

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Rac deletion in osteoclasts causes severe osteopetrosis

6 July 2018

1 reference

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Negative regulation of osteoclastogenesis and bone resorption by cytokines and transcriptional repressors

6 July 2018

1 reference

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Degrading devices: invadosomes in proteolytic cell invasion

6 July 2018

1 reference

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Gelsolin-independent podosome formation in dendritic cells

6 July 2018

1 reference

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Podosome rings generate forces that drive saltatory osteoclast migration

6 July 2018

1 reference

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The Rac1 exchange factor Dock5 is essential for bone resorption by osteoclasts

6 July 2018

1 reference

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Kindlin-3–mediated signaling from multiple integrin classes is required for osteoclast-mediated bone resorption

6 July 2018

1 reference

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Leptin-dependent serotonin control of appetite: temporal specificity, transcriptional regulation, and therapeutic implications

6 July 2018

1 reference

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Dynamics of podosome stiffness revealed by atomic force microscopy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

The cortactin-binding domain of WIP is essential for podosome formation and extracellular matrix degradation by murine dendritic cells

6 July 2018

1 reference

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β1A integrin is a master regulator of invadosome organization and function.

6 July 2018

1 reference

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Bone Is Not Essential for Osteoclast Activation

6 July 2018

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Insulin signaling in osteoblasts integrates bone remodeling and energy metabolism

6 July 2018

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The formin FRL1 (FMNL1) is an essential component of macrophage podosomes

6 July 2018

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Role of WASP in cell polarity and podosome dynamics of myeloid cells

6 July 2018

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A comparison of osteoclast resorption pits on bone with titanium and zirconia surfaces

6 July 2018

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Invadosomes: intriguing structures with promise.

6 July 2018

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TGFbeta-induced endothelial podosomes mediate basement membrane collagen degradation in arterial vessels

6 July 2018

1 reference

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Osteoclast motility: putting the brakes on bone resorption.

6 July 2018

1 reference

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Protein tyrosine phosphatase epsilon regulates integrin-mediated podosome stability in osteoclasts by activating Src.

6 July 2018

1 reference

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c-Cbl and Cbl-b act redundantly to protect osteoclasts from apoptosis and to displace HDAC6 from beta-tubulin, stabilizing microtubules and podosomes

6 July 2018

1 reference

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Dynamin reduces Pyk2 Y402 phosphorylation and SRC binding in osteoclasts

6 July 2018

1 reference

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CD45 regulates retention, motility, and numbers of hematopoietic progenitors, and affects osteoclast remodeling of metaphyseal trabecules

6 July 2018

1 reference

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Vesicular trafficking in osteoclasts

6 July 2018

1 reference

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Rho GTPases in cancer cell biology

6 July 2018

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The role of NFAT in osteoclast formation

6 July 2018

1 reference

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The tyrosine kinase activity of c-Src regulates actin dynamics and organization of podosomes in osteoclasts

6 July 2018

1 reference

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WASP-interacting protein (WIP): working in polymerisation and much more

6 July 2018

1 reference

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CD44 and beta3 integrin organize two functionally distinct actin-based domains in osteoclasts

6 July 2018

1 reference

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Defective microtubule-dependent podosome organization in osteoclasts leads to increased bone density in Pyk2(-/-) mice

6 July 2018

1 reference

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Syk, c-Src, the alphavbeta3 integrin, and ITAM immunoreceptors, in concert, regulate osteoclastic bone resorption

6 July 2018

1 reference

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Murine dendritic cell transdifferentiation into osteoclasts is differentially regulated by innate and adaptive cytokines

6 July 2018

1 reference

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The architecture of the adhesive apparatus of cultured osteoclasts: from podosome formation to sealing zone assembly

6 July 2018

1 reference

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WIP is a chaperone for Wiskott-Aldrich syndrome protein (WASP).

6 July 2018

1 reference

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Involvement of the Src-cortactin pathway in podosome formation and turnover during polarization of cultured osteoclasts

6 July 2018

1 reference

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Formation of a WIP-, WASp-, actin-, and myosin IIA-containing multiprotein complex in activated NK cells and its alteration by KIR inhibitory signaling

6 July 2018

1 reference

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Podosome and sealing zone: specificity of the osteoclast model

6 July 2018

1 reference

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6 July 2018

The leukocyte podosome

1 reference

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The molecular dynamics of osteoclast adhesions

6 July 2018

1 reference

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The role(s) of Src kinase and Cbl proteins in the regulation of osteoclast differentiation and function

6 July 2018

1 reference

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Dynamin forms a Src kinase-sensitive complex with Cbl and regulates podosomes and osteoclast activity

6 July 2018

1 reference

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Acidification of the osteoclastic resorption compartment provides insight into the coupling of bone formation to bone resorption.

6 July 2018

1 reference

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Wiskott-Aldrich syndrome protein and the cytoskeletal dynamics of dendritic cells

6 July 2018

1 reference

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Apatite-mediated actin dynamics in resorbing osteoclasts

6 July 2018

1 reference

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Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle

6 July 2018

1 reference

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The origins of osteoclasts

6 July 2018

1 reference

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Erk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASP

6 July 2018

1 reference

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Resorbability of bone substitute biomaterials by human osteoclasts

6 July 2018

1 reference

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Human primary osteoclasts: in vitro generation and applications as pharmacological and clinical assay

6 July 2018

1 reference

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6 July 2018

1 reference

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Podosome formation in cultured A7r5 vascular smooth muscle cells requires Arp2/3-dependent de-novo actin polymerization at discrete microdomains.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Actin can reorganize into podosomes in aortic endothelial cells, a process controlled by Cdc42 and RhoA.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Dynamic changes in the osteoclast cytoskeleton in response to growth factors and cell attachment are controlled by beta3 integrin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Intracellular membrane trafficking in bone resorbing osteoclasts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Cortactin interacts with WIP in regulating Arp2/3 activation and membrane protrusion

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Podosomes display actin turnover and dynamic self-organization in osteoclasts expressing actin-green fluorescent protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Flt3 macrophage precursors commit sequentially to osteoclasts, dendritic cells and microglia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

SHIP-deficient mice are severely osteoporotic due to increased numbers of hyper-resorptive osteoclasts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Osteoclastic acidification pathways during bone resorption

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

TRANCE/RANKL knockout mice are protected from bone erosion in a serum transfer model of arthritis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Microtubule-dependent formation of podosomal adhesion structures in primary human macrophages

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Gelsolin and ADF/cofilin enhance the actin dynamics of motile cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Integrins and signaling in osteoclast function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Rho and Rac exert antagonistic functions on spreading of macrophage-derived multinucleated cells and are not required for actin fiber formation.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

CD44 cell adhesion molecules

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Gelsolin deficiency blocks podosome assembly and produces increased bone mass and strength

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Mice lacking beta3 integrins are osteosclerotic because of dysfunctional osteoclasts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

RANK is essential for osteoclast and lymph node development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Osteopetrosis and osteoporosis: two sides of the same coin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Wiskott-Aldrich syndrome protein regulates podosomes in primary human macrophages

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Rac-GTPase, osteoclast cytoskeleton and bone resorption

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Beta3-integrin-deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

TRANCE is necessary and sufficient for osteoblast-mediated activation of bone resorption in osteoclasts.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Osteoclast differentiation factor (ODF) induces osteoclast-like cell formation in human peripheral blood mononuclear cell cultures.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Substrate recognition by osteoclast precursors induces C-src/microtubule association.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Knockouts of Src-family kinases: stiff bones, wimpy T cells, and bad memories.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Cortactin, an 80/85-kilodalton pp60src substrate, is a filamentous actin-binding protein enriched in the cell cortex

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Cell-substratum interaction of cultured avian osteoclasts is mediated by specific adhesion structures

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Osteoclasts and monocytes have similar cytoskeletal structures and adhesion property in vitro

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Identification of gelsolin, a Ca2 -dependent regulatory protein of actin gel-sol transformation, and its intracellular distribution in a variety of cells and tissues

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Cell-mediated extracellular acidification and bone resorption: evidence for a low pH in resorbing lacunae and localization of a 100-kD lysosomal membrane protein at the osteoclast ruffled border

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Paxillin: a new vinculin-binding protein present in focal adhesions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Osteoclasts express high levels of pp60c-src in association with intracellular membranes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Podosomes are dispensable for osteoclast differentiation and migration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

p130Cas, Crk-associated substrate, plays important roles in osteoclastic bone resorption

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Internal dynamics of actin structures involved in the cell motility and adhesion: Modeling of the podosomes at the molecular level

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Genome-wide expression analyses establish dendritic cells as a new osteoclast precursor able to generate bone-resorbing cells more efficiently than monocytes

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Identifying the relative contributions of Rac1 and Rac2 to osteoclastogenesis

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

A novel Rho-mDia2-HDAC6 pathway controls podosome patterning through microtubule acetylation in osteoclasts

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Vav3 regulates osteoclast function and bone mass

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Crosstalk between cell adhesion molecules: vinculin as a paradigm for regulation by conformation

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Energy-filtered electron microscopy reveals that talin is a highly flexible protein composed of a series of globular domains.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

The small GTP-binding protein, rho p21, is involved in bone resorption by regulating cytoskeletal organization in osteoclasts.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Blood leukocytes and macrophages of various phenotypes have distinct abilities to form podosomes and to migrate in 3D environments

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198343

Biochemical characterization of human osteoclast integrins. Osteoclasts express alpha v beta 3, alpha 2 beta 1, and alpha v beta 1 integrins

27 October 2018

1 reference

12 December 2020

The origin of dendritic cells

1 reference

12 December 2020

Rho-A is critical for osteoclast podosome organization, motility, and bone resorption

1 reference

12 December 2020

Microelectrode studies on the acid microenvironment beneath adherent macrophages and osteoclasts*1

1 reference

12 December 2020

Osteoclast ruffled border has distinct subdomains for secretion and degraded matrix uptake

1 reference

12 December 2020

Pediatric bone marrow transplantation for leukemia and aplastic anemia. Report of 222 cases transplanted in a single center

1 reference

12 December 2020

Immature dendritic cell transdifferentiation into osteoclasts: a novel pathway sustained by the rheumatoid arthritis microenvironment

1 reference

12 December 2020

Bone marrow microenvironment controls the in vivo differentiation of murine dendritic cells into osteoclasts

1 reference

12 December 2020

Identifiers

DOI

10.4161/CAM.27840

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24714644 AND SRC:MED&resulttype=core&format=json

13 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24714644 AND SRC:MED&resulttype=core&format=json

13 March 2020

PubMed publication ID

24714644

1 reference