Comparison of the pharmacological effects of a novel selective androgen receptor modulator, the 5alpha-reductase inhibitor finasteride, and the antiandrogen hydroxyflutamide in intact rats: new approach for benign prostate hyperplasia. (Q34340804)

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English	Comparison of the pharmacological effects of a novel selective androgen receptor modulator, the 5alpha-reductase inhibitor finasteride, and the antiandrogen hydroxyflutamide in intact rats: new approach for benign prostate hyperplasia.	scientific article

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31 December 2019

Comparison of the pharmacological effects of a novel selective androgen receptor modulator, the 5alpha-reductase inhibitor finasteride, and the antiandrogen hydroxyflutamide in intact rats: new approach for benign prostate hyperplasia (English)

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31 December 2019

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31 December 2019

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Wenqing Gao

1

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31 December 2019

Jeffrey D Kearbey

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31 December 2019

Vipin A Nair

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31 December 2019

Kiwon Chung

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31 December 2019

A F Parlow

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31 December 2019

Duane D Miller

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31 December 2019

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12 August 2004

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31 December 2019

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31 December 2019

145

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31 December 2019

12

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31 December 2019

5420-5428

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31 December 2019

Therapeutic androgen receptor ligands

1 reference

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6 July 2018

Pharmacokinetics of S-3-(4-acetylamino-phenoxy)-2-hydroxy-2-methyl-N-(4-nitro- 3-trifluoromethyl-phenyl)-propionamide in rats, a non-steroidal selective androgen receptor modulator

1 reference

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6 July 2018

Design, synthesis, and biological characterization of metabolically stable selective androgen receptor modulators

1 reference

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6 July 2018

Long-term 6-year experience with finasteride in patients with benign prostatic hyperplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2098692

6 July 2018

Pharmacodynamics of selective androgen receptor modulators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2098692

6 July 2018

Pharmacology, pharmacokinetics, and metabolism of acetothiolutamide, a novel nonsteroidal agonist for the androgen receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2098692

6 July 2018

Key structural features of nonsteroidal ligands for binding and activation of the androgen receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2098692

6 July 2018

Novel nonsteroidal ligands with high binding affinity and potent functional activity for the androgen receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2098692

6 July 2018

Update on the medical management of benign prostatic hyperplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2098692

6 July 2018

Selective androgen receptor modulators (SARMs): a novel approach to androgen therapy for the new millennium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2098692

6 July 2018

Long-Term Effects of Finasteride in Patients with Benign Prostatic Hyperplasia: A Double-Blind, Placebo-Controlled, Multicenter Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2098692

6 July 2018

Discovery of Nonsteroidal Androgens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2098692

6 July 2018

The effect of finasteride on the risk of acute urinary retention and the need for surgical treatment among men with benign prostatic hyperplasia. Finasteride Long-Term Efficacy and Safety Study Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2098692

6 July 2018

Bicalutamide (Casodex®) in the treatment of prostate cancer: History of clinical development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2098692

6 July 2018

Relative potency of testosterone and dihydrotestosterone in preventing atrophy and apoptosis in the prostate of the castrated rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2098692

6 July 2018

A dose-response study of the effect of flutamide on benign prostatic hyperplasia: results of a multicenter study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2098692

6 July 2018

The preclinical development of bicalutamide: pharmacodynamics and mechanism of action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2098692

6 July 2018

The molecular genetics of steroid 5 alpha-reductases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2098692

6 July 2018

Tissue distribution and ontogeny of steroid 5 alpha-reductase isozyme expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2098692

6 July 2018

5 alpha-reductase inhibitors for the treatment of benign prostatic hyperplasia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2098692

6 July 2018

Biological Actions of Androgens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2098692

6 July 2018

Changing Approaches in the Treatment of Benign Prostatic Hyperplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2098692

6 July 2018

Benign Prostatic Hyperplasia: Pathogenesis and Medical Therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2098692

6 July 2018

Tissue distribution and kinetic characteristics of rat steroid 5 alpha-reductase isozymes. Evidence for distinct physiological functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2098692

6 July 2018

Finasteride, an inhibitor of 5 alpha-reductase, suppresses prostatic dihydrotestosterone in men with benign prostatic hyperplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2098692

6 July 2018

Feasibility and potential gains of enhancing the subacute rat study protocol (OECD test guideline no. 407) by additional parameters selected to determine endocrine modulation. A pre-validation study to determine endocrine-mediated effects of the ant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2098692

27 October 2018

Comparison of histological compositions and apoptosis in canine spontaneous benign prostatic hyperplasia treated with androgen suppressive agents chlormadinone acetate and finasteride

1 reference

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27 October 2018

Morphological and hormonal changes in the ventral and dorsolateral prostatic lobes of rats treated with finasteride, a 5-Alpha reductase Inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15308613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Androgen metabolism in the prostate of the finasteride-treated, adult rat: a possible explanation for the differential action of testosterone and 5 alpha-dihydrotestosterone during development of the male urogenital tract

1 reference

https://pubmed.ncbi.nlm.nih.gov/15308613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of finasteride (MK-906), a 5 alpha-reductase inhibitor, on circulating androgens in male volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/15308613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Medical management of benign prostatic hyperplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15308613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for atrophy and apoptosis in the ventral prostate of rats given the 5 alpha-reductase inhibitor finasteride

1 reference

https://pubmed.ncbi.nlm.nih.gov/15308613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of finasteride on the rat ventral prostate

1 reference

https://pubmed.ncbi.nlm.nih.gov/15308613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of Chinese hamster ovary cell lines expressing human steroid 5 alpha-reductase isozymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15308613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dihydrotestosterone and the concept of 5α-reductase inhibition in human benign prostatic hyperplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15308613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Androgen-induced regrowth in the castrated rat ventral prostate: role of 5alpha-reductase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15308613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relative potency of antiandrogens with reference to intracellular testosterone in the rat prostate

1 reference

https://pubmed.ncbi.nlm.nih.gov/15308613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1210/EN.2004-0627

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15308613 AND SRC:MED&resulttype=core&format=json

31 December 2019

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31 December 2019

PubMed publication ID

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31 December 2019

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