Extracellular NAD shapes the Foxp3 regulatory T cell compartment through the ART2-P2X7 pathway (Q34340613)

1 August 2017

title

Extracellular NAD shapes the Foxp3 regulatory T cell compartment through the ART2-P2X7 pathway (English)

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1 August 2017

7

Friedrich Koch-Nolte

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Björn Rissiek

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object named as

Björn Rissiek

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author name string

Sandra Hubert

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1 August 2017

Björn Rissiek

2

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1 August 2017

Katjana Klages

3

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1 August 2017

Jochen Huehn

4

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1 August 2017

Tim Sparwasser

5

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1 August 2017

Friedrich Haag

6

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1 August 2017

Olivier Boyer

8

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1 August 2017

Michel Seman

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1 August 2017

Sahil Adriouch

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1 August 2017

language of work or name

English

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publication date

25 October 2010

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Journal of Experimental Medicine

1 August 2017

published in

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1 August 2017

volume

207

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1 August 2017

issue

12

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1 August 2017

page(s)

2561-2568

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A recombinant heavy chain antibody approach blocks ART2 mediated deletion of an iNKT cell population that upon activation inhibits autoimmune diabetes

1 August 2017

cites work

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ADP-ribosylation at R125 gates the P2X7 ion channel by presenting a covalent ligand to its nucleotide binding site

6 July 2018

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Single domain antibodies from llama effectively and specifically block T cell ecto-ADP-ribosyltransferase ART2.2 in vivo

6 July 2018

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Selective depletion of Foxp3 regulatory T cells induces a scurfy-like disease

6 July 2018

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Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies

6 July 2018

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6 July 2018

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High sensitivity of CD4 CD25 regulatory T cells to extracellular metabolites nicotinamide adenine dinucleotide and ATP: a role for P2X7 receptors

6 July 2018

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6 July 2018

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FOXP3 acts as a rheostat of the immune response

6 July 2018

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6 July 2018

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Foxp3 programs the development and function of CD4 CD25 regulatory T cells

6 July 2018

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Control of regulatory T cell development by the transcription factor Foxp3

6 July 2018

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6 July 2018

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6 July 2018

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Cyclic ADP-ribose production by CD38 regulates intracellular calcium release, extracellular calcium influx and chemotaxis in neutrophils and is required for bacterial clearance in vivo

6 July 2018

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6 July 2018

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Altered cytokine production in mice lacking P2X(7) receptors

6 July 2018

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6 July 2018

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Mice deficient for the ecto-nicotinamide adenine dinucleotide glycohydrolase CD38 exhibit altered humoral immune responses

6 July 2018

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NAD released during inflammation participates in T cell homeostasis by inducing ART2-mediated death of naive T cells in vivo

6 July 2018

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A self-restricted CD38-connexin 43 cross-talk affects NAD and cyclic ADP-ribose metabolism and regulates intracellular calcium in 3T3 fibroblasts

21 January 2018

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CD4 CD25 CD62 T-regulatory cell subset has optimal suppressive and proliferative potential

21 January 2018

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CD38 controls ADP-ribosyltransferase-2-catalyzed ADP-ribosylation of T cell surface proteins

21 January 2018

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NAD and ATP released from injured cells induce P2X7-dependent shedding of CD62L and externalization of phosphatidylserine by murine T cells

21 January 2018

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NAD-induced T cell death: ADP-ribosylation of cell surface proteins by ART2 activates the cytolytic P2X7 purinoceptor

21 January 2018

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Targeting Tumor Antigens to Secreted Membrane Vesicles In vivo Induces Efficient Antitumor Immune Responses

21 January 2018

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A new monoclonal antibody detects a developmentally regulated mouse ecto-ADP-ribosyltransferase on T cells: subset distribution, inbred strain variation, and modulation upon T cell activation.

21 January 2018

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Only the CD62L subpopulation of CD4 CD25 regulatory T cells protects from lethal acute GVHD

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20975043

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1084/JEM.20091154

1 reference

1 August 2017

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1 August 2017

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